Detailed information NTG0834747

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: U2S93_RS15545
• Genome accession: NZ_CP140431
• Coordinates: 3275473..3278022 (-)
• Length: 849 a.a.
• NCBI ID: WP_003139311.1
• Uniprot ID: A0A0H2ZBC1
• Organism: Pseudomonas aeruginosa strain 2023CK-01249
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3270473..3283022

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U2S93_RS15520 (U2S93_15520)	-	3270752..3271147 (+)	396	WP_003089513.1	DUF4280 domain-containing protein	-
U2S93_RS15525 (U2S93_15525)	-	3271170..3271706 (-)	537	WP_003131532.1	toxin-antitoxin system YwqK family antitoxin	-
U2S93_RS15530 (U2S93_15530)	tssI	3271717..3273723 (-)	2007	WP_022580991.1	type VI secretion system tip protein VgrG	-
U2S93_RS15535 (U2S93_15535)	-	3273760..3274827 (-)	1068	WP_022580990.1	M91 family zinc metallopeptidase	-
U2S93_RS15540 (U2S93_15540)	-	3274866..3275399 (-)	534	WP_003089506.1	hypothetical protein	-
U2S93_RS15545 (U2S93_15545)	clpC	3275473..3278022 (-)	2550	WP_003139311.1	type VI secretion system ATPase TssH	Regulator
U2S93_RS15550 (U2S93_15550)	tssG	3278024..3279040 (-)	1017	WP_003089501.1	type VI secretion system baseplate subunit TssG	-
U2S93_RS15555 (U2S93_15555)	tssF	3279004..3280797 (-)	1794	WP_003089497.1	type VI secretion system baseplate subunit TssF	-
U2S93_RS15560 (U2S93_15560)	tssE	3280781..3281206 (-)	426	WP_003089496.1	type VI secretion system baseplate subunit TssE	-
U2S93_RS15565 (U2S93_15565)	-	3281219..3281716 (-)	498	WP_003089495.1	Hcp family type VI secretion system effector	-

Sequence

Protein

• Length: 849 a.a.
• Molecular weight: 92457.70 Da
• Isoelectric Point: 5.1045

>NTDB_id=834747 U2S93_RS15545 WP_003139311.1 3275473..3278022(-) (clpC) [Pseudomonas aeruginosa strain 2023CK-01249]
MELAALIGRLNPDCRRALERAAQRCLQRTHHYVEIEHLLLELLDIDGGDFACLLPRFGLERDALVAEINLSLELFKAGNT
RTPALSAHTIGLLEDAVVHASVLGQAQIRSGLLLLALLDREERRALLLNSASSLLRIPHEALQANLLEWIQTSREQPPAP
NRPAAGGDKPESAPDPLLDQYTQDLTAEARAGRIDPIVGRDGEIRQCVDILLRRRQNNPILVGAPGVGKTAVVEGLALRI
AAGEVPPSLQEVILRVLDLGLLQAGASMKGEFEQRLKGVIDAVRNSAQPIILFIDEAHTLIGAGGAEGGSDAANLLKPAL
ARGELRTLAATTWLEYKKYFEKDPALTRRFQLVQVEEPDEATAVEMLRGVAGKLEQHHGVQIMDAAIVDAVKLSHRYISG
RQLPDKAISVLDTACARVALGQHDVPPPLESLRHREQALEEELQRLRREQATGLDHSARITALESESGDNRRTIRELETR
WDEEREAVRELLDTRRELLALSESADAAKPDEELDGRIDHLAAELARLAAGLEAIRQDDPLVPEQVDSRTVAAVIAGWTG
IPVGKMLADEAHAIRSLAQRMGQRVMGQEAALGAIAQRIQAYRAGLSDPAKPVGVFLLPGPTGVGKTETAYALADALYGG
ERNLISINLSEYQEAHTVSQLKGAPPGYVGYGSGGVLTEAVRRKPYSVVLLDEIEKAHPDVLEAFYNVFDKGVMEDGTGL
VVDFRNTVILATSNVGAELLLDSPAEQVATPAFDERLRKVLLQTFRPAFLARMTVVPYRPLEEATLEGIVVAKLEKLRER
YKAATGKQFDFDPAIVKAVLAKCSAAGARDIENVLMAQVTGKLAEWVLE

Nucleotide

• Length: 2550 bp

>NTDB_id=834747 U2S93_RS15545 WP_003139311.1 3275473..3278022(-) (clpC) [Pseudomonas aeruginosa strain 2023CK-01249]
ATGGAACTCGCCGCCCTGATCGGCCGCCTCAACCCGGACTGTCGCCGCGCCCTGGAGCGCGCCGCGCAACGCTGCCTGCA
ACGCACCCATCATTACGTAGAGATCGAGCACCTGCTGCTGGAGCTGCTGGACATCGACGGCGGCGACTTCGCCTGCCTGC
TGCCGCGCTTCGGCCTGGAGCGCGACGCCCTGGTCGCCGAGATCAACCTGTCGCTGGAGCTGTTCAAGGCCGGCAATACC
CGCACTCCGGCGCTGTCCGCGCACACCATCGGCCTGCTCGAGGACGCCGTGGTCCACGCCAGCGTGCTCGGCCAGGCGCA
GATCCGTTCCGGCCTGCTGCTGCTCGCCCTGCTCGACCGCGAGGAGCGCCGCGCCCTGCTGCTGAACAGCGCGTCGTCGC
TGCTGCGGATTCCCCACGAGGCCTTGCAGGCCAACCTGCTGGAGTGGATCCAGACCTCCCGCGAACAGCCGCCCGCGCCG
AACCGCCCGGCGGCAGGCGGCGACAAGCCGGAAAGCGCCCCGGACCCGCTGCTCGACCAGTACACCCAGGACCTCACCGC
CGAAGCCCGCGCCGGGCGCATCGACCCCATCGTCGGGCGCGACGGGGAGATCCGCCAGTGCGTCGACATCCTCCTGCGCC
GGCGGCAGAACAACCCGATCCTGGTCGGCGCGCCGGGCGTCGGCAAGACCGCAGTGGTCGAGGGCCTGGCCCTGCGCATC
GCCGCCGGCGAGGTGCCGCCGTCGTTGCAGGAGGTGATCCTGCGGGTGCTCGACCTCGGCCTGTTGCAGGCCGGCGCCAG
CATGAAGGGCGAGTTCGAGCAGCGCCTCAAGGGGGTAATCGACGCCGTGCGCAACAGCGCGCAGCCGATCATCCTGTTCA
TCGACGAGGCGCACACGCTGATCGGCGCCGGCGGCGCGGAAGGCGGCAGCGACGCCGCCAACCTGCTCAAGCCGGCCCTG
GCGCGCGGCGAGTTGCGCACCCTGGCGGCCACCACCTGGCTGGAATACAAGAAATACTTCGAGAAGGACCCGGCGCTGAC
CCGGCGCTTCCAACTGGTCCAGGTCGAGGAGCCGGACGAGGCCACCGCCGTGGAGATGCTGCGCGGCGTCGCCGGCAAGC
TGGAACAGCATCACGGCGTGCAGATCATGGACGCGGCCATCGTCGATGCGGTGAAGCTGTCGCACCGCTACATCTCCGGC
CGCCAGTTACCGGACAAGGCGATCAGCGTGCTCGACACCGCCTGCGCGCGGGTCGCCCTCGGCCAGCACGACGTGCCGCC
GCCGCTGGAAAGCCTGCGCCACCGCGAGCAGGCGCTGGAAGAGGAATTGCAGCGGCTGCGCCGGGAACAGGCCACCGGCC
TCGACCACAGCGCGCGTATCACCGCCCTGGAAAGCGAGTCGGGCGATAACCGCCGGACCATCCGCGAGCTGGAGACCCGC
TGGGACGAGGAACGCGAAGCGGTGCGCGAACTGCTCGACACCCGCCGCGAATTGCTGGCCCTCAGCGAAAGCGCCGACGC
GGCCAAGCCCGACGAGGAACTGGACGGTCGCATCGACCACCTGGCCGCCGAACTGGCGCGCCTGGCGGCCGGCCTCGAAG
CCATCCGCCAGGACGACCCGCTGGTTCCCGAGCAGGTGGACTCGCGTACCGTGGCCGCGGTGATCGCCGGCTGGACCGGC
ATCCCGGTGGGCAAGATGCTCGCCGACGAAGCCCACGCCATCCGTTCCCTGGCGCAACGAATGGGCCAGCGGGTGATGGG
CCAGGAGGCCGCCCTGGGCGCCATCGCCCAGCGCATCCAGGCCTATCGCGCCGGACTCAGCGACCCGGCCAAGCCGGTCG
GCGTATTCCTCCTGCCCGGCCCCACCGGCGTGGGCAAGACCGAGACCGCCTACGCCCTGGCCGACGCCCTCTACGGCGGC
GAACGCAACCTGATCAGCATCAACCTCTCCGAGTACCAGGAGGCCCACACCGTCAGCCAGCTCAAGGGCGCCCCGCCCGG
CTACGTCGGCTACGGCAGCGGCGGCGTGCTCACCGAAGCGGTGCGCCGCAAGCCCTATTCGGTGGTGCTGCTGGACGAGA
TCGAGAAAGCCCATCCGGACGTGCTGGAAGCCTTCTACAACGTGTTCGACAAGGGTGTGATGGAAGACGGCACCGGCCTG
GTGGTGGACTTCAGGAACACCGTGATCCTCGCCACCAGCAACGTCGGCGCCGAACTGCTGCTGGACAGCCCGGCCGAACA
GGTCGCCACCCCGGCCTTCGACGAGCGCCTGCGCAAAGTCTTGCTGCAAACCTTCCGCCCGGCGTTCCTCGCGCGCATGA
CCGTGGTGCCTTACCGGCCGCTGGAGGAAGCCACCCTGGAAGGCATCGTCGTGGCCAAGCTGGAAAAACTGCGGGAACGC
TACAAGGCCGCTACCGGCAAACAGTTCGACTTCGACCCGGCCATCGTCAAGGCCGTGCTCGCCAAGTGCAGCGCGGCGGG
CGCGCGGGATATCGAGAACGTGCTGATGGCGCAGGTGACGGGGAAGTTGGCGGAGTGGGTACTCGAATGA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (611-775)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (781-848)

• AAA lid domain (AAA_lid_9) (360-453)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (21-71)

• ATPase family associated with various cellular activities (AAA) (AAA) (220-332)

3D structure

• AlphaFold DB: A0A0H2ZBC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	37.166	100	0.377