Detailed information    

insolico Bioinformatically predicted

Overview

Name   comC   Type   Machinery gene
Locus tag   Hhaem_RS01375 Genome accession   NZ_AP024093
Coordinates   278768..279289 (-) Length   173 a.a.
NCBI ID   WP_118845892.1    Uniprot ID   -
Organism   Haemophilus haemolyticus strain 2019-19     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 273768..284289
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Hhaem_RS01345 (Hhaem_02690) - 274152..274742 (-) 591 WP_105893546.1 YjaG family protein -
  Hhaem_RS01350 (Hhaem_02700) nudC 274778..275572 (-) 795 WP_223893819.1 NAD(+) diphosphatase -
  Hhaem_RS01355 (Hhaem_02710) nfuA 275640..276236 (-) 597 WP_223893820.1 Fe-S biogenesis protein NfuA -
  Hhaem_RS01360 (Hhaem_02720) - 276312..276998 (-) 687 WP_223894288.1 ComF family protein -
  Hhaem_RS01365 (Hhaem_02730) comE 277011..278348 (-) 1338 WP_223893822.1 type IV pilus secretin PilQ family protein Machinery gene
  Hhaem_RS01370 (Hhaem_02740) comD 278358..278771 (-) 414 WP_223893823.1 pilus assembly protein PilP Machinery gene
  Hhaem_RS01375 (Hhaem_02750) comC 278768..279289 (-) 522 WP_118845892.1 competence protein ComC Machinery gene
  Hhaem_RS01380 (Hhaem_02760) comB 279286..279792 (-) 507 WP_223893824.1 competence protein B Machinery gene
  Hhaem_RS01385 (Hhaem_02770) comA 279793..280590 (-) 798 WP_223893825.1 competence protein ComA Machinery gene
  Hhaem_RS01390 (Hhaem_02780) - 280689..283292 (+) 2604 WP_223893826.1 penicillin-binding protein 1A -
  Hhaem_RS01395 (Hhaem_02790) - 283365..284210 (+) 846 WP_223893827.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -

Sequence

Protein


Download         Length: 173 a.a.        Molecular weight: 19893.06 Da        Isoelectric Point: 9.8951

>NTDB_id=83424 Hhaem_RS01375 WP_118845892.1 278768..279289(-) (comC) [Haemophilus haemolyticus strain 2019-19]
MKAFFNDPFTPFGKWLSQPFYVHGLTFLLLLSAVIFRPVLDYIEGSSRFHEIESELAGKRSELLHQQKILTSLQQQSESR
KLSPELAAQIMPLNKQIQRLVARNGLSQNLRWEMGQQPILHLQLTGHFEKTKTFLTALLANTSQLSVSRLQFMKPEDGPL
QTEIIFQLDKEAK

Nucleotide


Download         Length: 522 bp        

>NTDB_id=83424 Hhaem_RS01375 WP_118845892.1 278768..279289(-) (comC) [Haemophilus haemolyticus strain 2019-19]
GTGAAAGCCTTTTTTAACGATCCTTTTACACCTTTTGGAAAATGGCTAAGTCAGCCTTTTTATGTGCACGGTTTAACTTT
TTTATTGTTATTAAGTGCGGTGATTTTTCGCCCCGTTTTAGATTATATCGAGGGGAGTTCGCGTTTCCATGAAATCGAAA
GTGAATTAGCAGGGAAACGATCAGAATTGTTGCATCAACAGAAAATTTTAACTTCTTTACAGCAGCAATCGGAAAGTCGA
AAACTTTCTCCAGAACTGGCTGCACAAATTATGCCTTTGAATAAACAAATTCAACGTTTAGTTGCGCGTAACGGTTTATC
TCAGAATTTACGTTGGGAAATGGGGCAACAGCCTATTTTGCATTTACAGCTTACTGGGCATTTTGAAAAAACGAAGACAT
TTTTAACCGCACTTTTAGCTAATACGTCACAGCTTTCTGTAAGTCGTCTGCAATTTATGAAACCCGAAGACGGCCCATTG
CAAACCGAGATCATTTTTCAGCTAGATAAGGAGGCAAAATGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC Haemophilus influenzae Rd KW20

94.798

100

0.948
  comC Haemophilus influenzae 86-028NP

94.22

100

0.942

Multiple sequence alignment