Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   U2W45_RS03870 Genome accession   NZ_CP140117
Coordinates   763122..763598 (+) Length   158 a.a.
NCBI ID   WP_010922230.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NV1     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 758122..768598
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U2W45_RS03845 (U2W45_03840) - 758163..758951 (+) 789 WP_002984887.1 Nif3-like dinuclear metal center hexameric protein -
  U2W45_RS03850 (U2W45_03845) - 758991..760097 (+) 1107 WP_011285493.1 NAD(P)/FAD-dependent oxidoreductase -
  U2W45_RS03855 (U2W45_03850) rfbA 760155..761024 (+) 870 WP_010922195.1 glucose-1-phosphate thymidylyltransferase RfbA -
  U2W45_RS03860 (U2W45_03855) - 761024..761617 (+) 594 WP_002990099.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  U2W45_RS03865 (U2W45_03860) rfbB 761861..762901 (+) 1041 WP_011285494.1 dTDP-glucose 4,6-dehydratase -
  U2W45_RS03870 (U2W45_03865) mutX 763122..763598 (+) 477 WP_010922230.1 NUDIX hydrolase Machinery gene
  U2W45_RS03875 (U2W45_03870) - 763656..764837 (+) 1182 WP_002990002.1 AI-2E family transporter -
  U2W45_RS03880 (U2W45_03875) - 764827..766074 (+) 1248 WP_010922231.1 tetratricopeptide repeat protein -
  U2W45_RS03885 (U2W45_03880) fbp54 766133..767785 (-) 1653 WP_010922232.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18452.64 Da        Isoelectric Point: 4.3268

>NTDB_id=833615 U2W45_RS03870 WP_010922230.1 763122..763598(+) (mutX) [Streptococcus pyogenes strain NV1]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRSFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=833615 U2W45_RS03870 WP_010922230.1 763122..763598(+) (mutX) [Streptococcus pyogenes strain NV1]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCAGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTTCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

69.62

100

0.696