Detailed information NTG0833578

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: QM338_RS13400
• Genome accession: NZ_CP125901
• Coordinates: 2673406..2674293 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain CHAL2
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2668406..2679293

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QM338_RS13370 (QM338_13370)	-	2668425..2668517 (+)	93	WP_010956583.1	hypothetical protein	-
QM338_RS13375 (QM338_13375)	-	2668625..2669122 (-)	498	WP_001065268.1	glutathione peroxidase	-
QM338_RS13380 (QM338_13380)	-	2669132..2669392 (-)	261	WP_001791974.1	hypothetical protein	-
QM338_RS13385 (QM338_13385)	-	2669774..2669887 (-)	114	Protein_2597	hypothetical protein	-
QM338_RS13390 (QM338_13390)	-	2670546..2672546 (-)	2001	WP_000776751.1	ABC transporter permease	-
QM338_RS13395 (QM338_13395)	-	2672543..2673298 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
QM338_RS13400 (QM338_13400)	braS	2673406..2674293 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
QM338_RS13405 (QM338_13405)	braR	2674304..2674969 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
QM338_RS13410 (QM338_13410)	-	2674995..2675195 (-)	201	WP_000604730.1	hypothetical protein	-
QM338_RS13415 (QM338_13415)	-	2675393..2676817 (+)	1425	WP_000953755.1	alkaline phosphatase	-
QM338_RS14030	-	2676877..2676978 (-)	102	WP_000731976.1	SE2200 family small protein	-
QM338_RS13425 (QM338_13425)	-	2677100..2677555 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
QM338_RS13430 (QM338_13430)	-	2677800..2678561 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=833578 QM338_RS13400 WP_000143425.1 2673406..2674293(-) (braS) [Staphylococcus aureus strain CHAL2]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=833578 QM338_RS13400 WP_000143425.1 2673406..2674293(-) (braS) [Staphylococcus aureus strain CHAL2]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1