Detailed information NTG0833572

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QM338_RS09575
• Genome accession: NZ_CP125901
• Coordinates: 1940764..1941807 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain CHAL2
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1935764..1946807

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QM338_RS09545 (QM338_09545)	-	1936185..1937441 (-)	1257	WP_001795108.1	aminopeptidase	-
QM338_RS09550 (QM338_09550)	-	1937444..1937644 (-)	201	WP_000180460.1	DUF1128 family protein	-
QM338_RS09555 (QM338_09555)	-	1937791..1938255 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
QM338_RS09560 (QM338_09560)	-	1938262..1938537 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
QM338_RS09565 (QM338_09565)	-	1938815..1940032 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
QM338_RS09570 (QM338_09570)	vraR	1940145..1940774 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
QM338_RS09575 (QM338_09575)	vraS	1940764..1941807 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
QM338_RS09580 (QM338_09580)	liaF	1941804..1942505 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
QM338_RS09585 (QM338_09585)	-	1942520..1942906 (-)	387	WP_001110179.1	hypothetical protein	-
QM338_RS09590 (QM338_09590)	map	1943123..1943881 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
QM338_RS09595 (QM338_09595)	-	1944412..1945398 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
QM338_RS09600 (QM338_09600)	-	1945829..1946242 (-)	414	WP_001557448.1	hypothetical protein	-
QM338_RS09605 (QM338_09605)	-	1946271..1946381 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=833572 QM338_RS09575 WP_001017131.1 1940764..1941807(-) (vraS) [Staphylococcus aureus strain CHAL2]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=833572 QM338_RS09575 WP_001017131.1 1940764..1941807(-) (vraS) [Staphylococcus aureus strain CHAL2]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1