Detailed information NTG0833493

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: QM341_RS13675
• Genome accession: NZ_CP125897
• Coordinates: 2703396..2704283 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain CHAL4
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2698396..2709283

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QM341_RS13645 (QM341_13645)	-	2698415..2698507 (+)	93	WP_010956583.1	hypothetical protein	-
QM341_RS13650 (QM341_13650)	-	2698615..2699112 (-)	498	WP_001065268.1	glutathione peroxidase	-
QM341_RS13655 (QM341_13655)	-	2699122..2699382 (-)	261	WP_001789910.1	hypothetical protein	-
QM341_RS13660 (QM341_13660)	-	2699764..2699877 (-)	114	WP_011447078.1	hypothetical protein	-
QM341_RS13665 (QM341_13665)	-	2700536..2702536 (-)	2001	WP_000776751.1	ABC transporter permease	-
QM341_RS13670 (QM341_13670)	-	2702533..2703288 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
QM341_RS13675 (QM341_13675)	braS	2703396..2704283 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
QM341_RS13680 (QM341_13680)	braR	2704294..2704959 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
QM341_RS13685 (QM341_13685)	-	2704985..2705185 (-)	201	WP_000604728.1	hypothetical protein	-
QM341_RS13690 (QM341_13690)	-	2705383..2706807 (+)	1425	WP_000953744.1	alkaline phosphatase	-
QM341_RS14275	-	2706867..2706968 (-)	102	WP_000731972.1	SE2200 family small protein	-
QM341_RS13700 (QM341_13700)	-	2707090..2707545 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
QM341_RS13705 (QM341_13705)	-	2707790..2708551 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=833493 QM341_RS13675 WP_000143419.1 2703396..2704283(-) (braS) [Staphylococcus aureus strain CHAL4]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=833493 QM341_RS13675 WP_000143419.1 2703396..2704283(-) (braS) [Staphylococcus aureus strain CHAL4]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997