Detailed information NTG0833452

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: QM342_RS13050
• Genome accession: NZ_CP125895
• Coordinates: 2637458..2638345 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain CHAL5
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2632458..2643345

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QM342_RS13020 (QM342_13020)	-	2632486..2632569 (+)	84	WP_031797553.1	hypothetical protein	-
QM342_RS13025 (QM342_13025)	-	2632677..2633174 (-)	498	WP_001065268.1	glutathione peroxidase	-
QM342_RS13030 (QM342_13030)	-	2633184..2633444 (-)	261	WP_001789307.1	hypothetical protein	-
QM342_RS13035 (QM342_13035)	-	2633826..2633939 (-)	114	WP_011447078.1	hypothetical protein	-
QM342_RS13040 (QM342_13040)	-	2634598..2636598 (-)	2001	WP_000776733.1	ABC transporter permease	-
QM342_RS13045 (QM342_13045)	-	2636595..2637350 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
QM342_RS13050 (QM342_13050)	braS	2637458..2638345 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
QM342_RS13055 (QM342_13055)	braR	2638356..2639021 (-)	666	WP_000697887.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
QM342_RS13060 (QM342_13060)	-	2639047..2639247 (-)	201	WP_000604727.1	hypothetical protein	-
QM342_RS13065 (QM342_13065)	-	2639445..2640869 (+)	1425	WP_000953744.1	alkaline phosphatase	-
QM342_RS13690	-	2640929..2641030 (-)	102	WP_000731972.1	SE2200 family small protein	-
QM342_RS13075 (QM342_13075)	-	2641152..2641607 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
QM342_RS13080 (QM342_13080)	-	2641852..2642613 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=833452 QM342_RS13050 WP_000143419.1 2637458..2638345(-) (braS) [Staphylococcus aureus strain CHAL5]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=833452 QM342_RS13050 WP_000143419.1 2637458..2638345(-) (braS) [Staphylococcus aureus strain CHAL5]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997