Detailed information NTG0833205

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: QM318_RS10840
• Genome accession: NZ_CP125867
• Coordinates: 2186726..2187613 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain 19-02247
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2181726..2192613

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QM318_RS10810 (QM318_10805)	-	2182458..2183219 (+)	762	WP_000323455.1	alpha/beta hydrolase family protein	-
QM318_RS10815 (QM318_10810)	-	2183464..2183919 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
QM318_RS10820 (QM318_10815)	-	2184041..2184142 (+)	102	WP_000731972.1	SE2200 family small protein	-
QM318_RS10825 (QM318_10820)	-	2184202..2185626 (-)	1425	WP_000953744.1	alkaline phosphatase	-
QM318_RS10830 (QM318_10825)	-	2185824..2186024 (+)	201	WP_000604728.1	hypothetical protein	-
QM318_RS10835 (QM318_10830)	braR	2186050..2186715 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
QM318_RS10840 (QM318_10835)	braS	2186726..2187613 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
QM318_RS10845 (QM318_10840)	-	2187721..2188476 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
QM318_RS10850 (QM318_10845)	-	2188473..2190473 (+)	2001	WP_000776751.1	ABC transporter permease	-
QM318_RS10855 (QM318_10850)	-	2191132..2191245 (+)	114	WP_001791776.1	hypothetical protein	-
QM318_RS10860 (QM318_10855)	-	2191627..2191887 (+)	261	WP_001789910.1	hypothetical protein	-
QM318_RS10865 (QM318_10860)	-	2191897..2192394 (+)	498	WP_001065268.1	glutathione peroxidase	-
QM318_RS10870 (QM318_10865)	-	2192502..2192594 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=833205 QM318_RS10840 WP_000143419.1 2186726..2187613(+) (braS) [Staphylococcus aureus strain 19-02247]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=833205 QM318_RS10840 WP_000143419.1 2186726..2187613(+) (braS) [Staphylococcus aureus strain 19-02247]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997