Detailed information NTG0833087

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: I3F59_RS24655
• Genome accession: NZ_CP140097
• Coordinates: 5609358..5611952 (-)
• Length: 864 a.a.
• NCBI ID: WP_240134527.1
• Uniprot ID: -
• Organism: Streptomyces sp. MUM 178J
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 5604358..5616952

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I3F59_RS24630 (I3F59_024630)	-	5604919..5605440 (-)	522	WP_240134433.1	DUF2617 family protein	-
I3F59_RS24635 (I3F59_024635)	-	5606376..5607560 (+)	1185	WP_240134434.1	pyridoxal phosphate-dependent aminotransferase	-
I3F59_RS24640 (I3F59_024640)	-	5607696..5608046 (-)	351	WP_240134435.1	hypothetical protein	-
I3F59_RS24645 (I3F59_024645)	-	5608043..5608528 (-)	486	WP_240134436.1	prevent-host-death family protein	-
I3F59_RS24650 (I3F59_024650)	-	5608690..5609229 (-)	540	WP_240134437.1	YbjN domain-containing protein	-
I3F59_RS24655 (I3F59_024655)	clpC	5609358..5611952 (-)	2595	WP_240134527.1	ATP-dependent chaperone ClpB	Regulator
I3F59_RS24660 (I3F59_024660)	-	5612062..5612475 (+)	414	WP_240134438.1	pyridoxamine 5'-phosphate oxidase family protein	-
I3F59_RS24665 (I3F59_024665)	-	5612723..5613040 (-)	318	WP_240134439.1	(2Fe-2S)-binding protein	-
I3F59_RS24670 (I3F59_024670)	-	5613037..5613324 (-)	288	WP_240134440.1	hypothetical protein	-
I3F59_RS24675 (I3F59_024675)	-	5613487..5614512 (+)	1026	WP_240134528.1	helix-turn-helix transcriptional regulator	-
I3F59_RS24680 (I3F59_024680)	-	5614956..5615411 (-)	456	WP_240134441.1	helix-turn-helix domain-containing protein	-
I3F59_RS24685 (I3F59_024685)	dnaJ	5615413..5616612 (-)	1200	WP_240134442.1	molecular chaperone DnaJ	-

Sequence

Protein

• Length: 864 a.a.
• Molecular weight: 94380.72 Da
• Isoelectric Point: 4.7666

>NTDB_id=833087 I3F59_RS24655 WP_240134527.1 5609358..5611952(-) (clpC) [Streptomyces sp. MUM 178J]
MDAELTNKSRAALNAATNRAVSAGHPDLTPAHLLLALLTGEENENITDLLAAVEADQAAVRSGAERALGGLPSVTGSTVA
PPQPNRDLLAVLAEADRQAKELGDEYLSTEHLLIATAAKGGPAGDVLTRQGATAKKLLAAFQSVRGGRRVTTPDPEAQYK
ALEKFGADFTAAAREGKLDPVIGRDQEIRRVVQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQRIVKGDVPESLRNKRLVA
LDLGAMVAGAKYRGEFEERLKTVLSEIKESDGQIITFIDELHTVVGAGAGGDSAMDAGNMLKPMLARGELRMVGATTLDE
YRERIEKDPALERRFQQVLVAEPTVEDTIAILRGLKGRYEAHHKVQIADGALVAAAALSDRYITSRFLPDKAIDLVDEAA
SRLRMEIDSSPVEIDELQRAVDRLRMEELALKNESDEASKQRLEKLRRDLADKEEELRGLTARWEKEKQGLNRVGELKER
LDQLRGQAERAERDGDLETASRLRYGDIRALERELEEASEAEQEAARDTMVKEEVGSDDIADVVASWTGIPAGRLLEGET
QKLLRMEDELGKRLIGQTEAVRAVSDAVRRSRAGVADPDRPTGSFLFLGPTGVGKTELAKALADFLFDDERAMVRIDMSE
YSEKHSVARLVGAPPGYVGYEEGGQLTEAVRRRPYSVVLLDEVEKAHPEVFDILLQVLDDGRLTDGQGRTVDFRNTILVL
TSNLGSQYLVEPLTTAEEKKQQVLKVVRASFKPEFLNRLDDLVVFSALAKEELTRIAELQIGRLADRLAERRLTLDVTPA
ALAWLADEGNDPAYGARPLRRLVQTAIGDRLAREILSGEVQDGDTVRVDRFGDDPDGGLIVGPA

Nucleotide

• Length: 2595 bp

>NTDB_id=833087 I3F59_RS24655 WP_240134527.1 5609358..5611952(-) (clpC) [Streptomyces sp. MUM 178J]
GTGGACGCCGAGCTGACCAACAAGAGCCGCGCCGCGTTGAACGCGGCCACCAACCGGGCCGTGTCGGCGGGGCACCCCGA
TCTCACCCCCGCGCATCTTCTCCTCGCCCTCCTCACGGGTGAGGAGAACGAGAACATCACCGACCTGCTGGCCGCCGTCG
AGGCGGACCAGGCGGCCGTGCGCTCCGGCGCCGAACGGGCCCTCGGCGGGCTGCCCAGCGTGACCGGCTCCACGGTCGCG
CCGCCCCAGCCCAACCGCGATCTGCTCGCCGTCCTCGCCGAGGCCGACCGGCAGGCCAAGGAACTGGGCGACGAGTACCT
CTCCACCGAGCACCTGCTGATCGCGACCGCCGCCAAGGGCGGCCCCGCAGGGGACGTCCTCACCCGGCAGGGCGCCACCG
CGAAGAAGCTGCTGGCGGCCTTCCAGTCGGTCCGCGGCGGGCGCCGGGTCACCACCCCCGACCCCGAGGCCCAGTACAAG
GCCCTGGAGAAGTTCGGCGCCGACTTCACCGCGGCCGCGCGCGAGGGCAAGCTGGACCCGGTCATCGGCCGGGACCAGGA
GATCCGCCGGGTCGTGCAGGTGCTCTCGCGCCGCACCAAGAACAACCCGGTGCTGATCGGCGAGCCGGGGGTCGGCAAGA
CGGCCGTGGTCGAGGGCCTCGCCCAGCGCATTGTCAAGGGCGACGTGCCGGAGTCCCTGCGCAACAAGCGGCTGGTCGCC
CTGGACCTCGGTGCAATGGTTGCGGGTGCGAAGTACCGCGGAGAGTTCGAGGAACGGCTGAAAACCGTCCTGTCCGAGAT
CAAGGAGAGCGACGGCCAGATCATCACCTTCATCGACGAGCTGCACACCGTCGTCGGCGCGGGCGCGGGCGGCGACTCGG
CCATGGACGCCGGCAACATGCTCAAGCCGATGCTGGCCCGCGGCGAGCTGCGCATGGTCGGCGCCACCACGCTGGACGAG
TACCGCGAGCGGATCGAGAAGGACCCGGCGCTGGAGCGCCGCTTCCAGCAGGTGCTGGTCGCCGAGCCGACGGTCGAGGA
CACCATCGCCATCCTGCGCGGACTCAAGGGCCGGTACGAGGCCCACCACAAGGTCCAGATCGCCGACGGCGCGCTGGTGG
CCGCCGCCGCCCTCTCCGACCGCTACATCACCTCCCGCTTCCTGCCCGACAAGGCCATCGACCTCGTCGACGAGGCGGCC
TCCCGGCTCCGTATGGAGATCGACTCCTCCCCGGTCGAGATCGACGAGCTGCAGCGCGCCGTCGACCGGCTGCGCATGGA
GGAGCTGGCGCTCAAGAACGAGTCCGACGAGGCCAGCAAGCAGCGGCTGGAGAAGCTGCGCCGCGACCTCGCCGACAAGG
AGGAGGAGCTCCGCGGACTCACCGCCCGCTGGGAGAAGGAGAAGCAGGGCCTCAACCGGGTCGGCGAGCTGAAGGAGCGG
CTCGACCAGCTGCGCGGCCAGGCCGAGCGTGCCGAGCGGGACGGCGACCTGGAGACCGCCTCCCGGCTCAGGTACGGGGA
CATCCGCGCCCTGGAACGCGAGCTGGAGGAGGCCAGCGAGGCCGAACAGGAGGCCGCCCGCGACACCATGGTCAAGGAGG
AGGTCGGCTCCGACGACATCGCCGACGTCGTCGCCTCCTGGACCGGCATCCCGGCCGGCCGGCTGCTGGAGGGCGAGACG
CAGAAGCTGCTGCGCATGGAGGACGAGCTGGGCAAGCGGCTGATCGGCCAGACCGAGGCGGTCCGGGCCGTCTCCGACGC
GGTGCGGCGCTCCCGGGCGGGCGTCGCCGACCCCGACCGCCCCACCGGCTCCTTCCTCTTCCTCGGCCCGACCGGCGTCG
GCAAGACGGAGCTGGCCAAGGCGCTCGCCGACTTCCTCTTCGACGACGAACGGGCCATGGTCCGCATCGACATGTCGGAG
TACAGCGAGAAGCACAGCGTCGCCCGCCTGGTCGGCGCGCCGCCCGGCTACGTCGGCTACGAGGAGGGCGGCCAGCTCAC
CGAGGCCGTACGCCGTCGCCCGTACAGCGTGGTGCTCCTGGACGAGGTGGAGAAGGCCCACCCCGAGGTCTTCGACATCC
TGCTCCAGGTCCTCGACGACGGCCGGCTGACCGACGGACAGGGCCGGACGGTGGATTTCCGCAACACCATCCTGGTCCTC
ACCTCCAACCTCGGCAGCCAGTATCTGGTCGAGCCCCTGACCACCGCGGAGGAGAAGAAGCAGCAGGTCCTGAAGGTGGT
GCGGGCCTCCTTCAAGCCCGAGTTCCTCAACCGGCTGGACGACCTGGTGGTCTTCTCCGCCCTTGCCAAGGAGGAGCTGA
CGAGGATCGCCGAGCTGCAGATCGGCAGACTGGCCGACCGGCTCGCCGAGCGCCGGCTCACCCTTGACGTCACCCCGGCC
GCGCTGGCCTGGCTGGCGGACGAGGGCAACGACCCGGCGTACGGGGCGCGGCCGCTGCGCCGTCTGGTGCAGACCGCGAT
CGGCGACCGCCTCGCCAGGGAGATCCTTTCGGGTGAGGTCCAGGACGGCGACACGGTCCGCGTCGACCGGTTCGGCGACG
ACCCGGACGGCGGGCTGATCGTGGGTCCGGCCTGA

Domains

Predicted by InterProScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-146)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (19-69)

• AAA domain (Cdc48 subfamily) (AAA_2) (600-761)

• ATPase family associated with various cellular activities (AAA) (AAA) (204-338)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (768-848)

• AAA lid domain (AAA_lid_9) (344-446)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	44.046	100	0.441
clpC	Lactococcus lactis subsp. cremoris KW2	47.902	79.977	0.383
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.328	81.944	0.38
clpE	Streptococcus mutans UA159	48.071	78.009	0.375
clpE	Streptococcus pneumoniae R6	46.423	79.282	0.368
clpE	Streptococcus pneumoniae TIGR4	46.423	79.282	0.368
clpE	Streptococcus pneumoniae Rx1	46.423	79.282	0.368
clpE	Streptococcus pneumoniae D39	46.423	79.282	0.368