Detailed information NTG0833083

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: I3F59_RS23620
• Genome accession: NZ_CP140097
• Coordinates: 5383546..5386071 (-)
• Length: 841 a.a.
• NCBI ID: WP_240134259.1
• Uniprot ID: -
• Organism: Streptomyces sp. MUM 178J
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 5378546..5391071

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I3F59_RS23605 (I3F59_023605)	-	5378655..5379323 (-)	669	WP_240134256.1	M23 family metallopeptidase	-
I3F59_RS23610 (I3F59_023610)	-	5379784..5383047 (+)	3264	WP_240134257.1	NACHT domain-containing protein	-
I3F59_RS23615 (I3F59_023615)	-	5383044..5383382 (+)	339	WP_240134258.1	trypco2 family protein	-
I3F59_RS23620 (I3F59_023620)	clpC	5383546..5386071 (-)	2526	WP_240134259.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
I3F59_RS23625 (I3F59_023625)	-	5386514..5387338 (+)	825	WP_240134260.1	SCO3374 family protein	-
I3F59_RS23630 (I3F59_023630)	-	5387317..5387649 (-)	333	WP_240134261.1	Lsr2 family protein	-
I3F59_RS23635 (I3F59_023635)	-	5387805..5388326 (-)	522	WP_240134262.1	amino-acid N-acetyltransferase	-
I3F59_RS23640 (I3F59_023640)	-	5388336..5388731 (-)	396	WP_240134263.1	BlaI/MecI/CopY family transcriptional regulator	-
I3F59_RS23645 (I3F59_023645)	-	5388873..5389046 (-)	174	WP_240134264.1	hypothetical protein	-
I3F59_RS23650 (I3F59_023650)	-	5389060..5389680 (-)	621	WP_240134509.1	hypothetical protein	-
I3F59_RS23655 (I3F59_023655)	-	5389879..5390676 (-)	798	WP_240134265.1	type III pantothenate kinase	-

Sequence

Protein

• Length: 841 a.a.
• Molecular weight: 93047.24 Da
• Isoelectric Point: 5.8271

>NTDB_id=833083 I3F59_RS23620 WP_240134259.1 5383546..5386071(-) (clpC) [Streptomyces sp. MUM 178J]
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKALESLGISLEAVRQQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGADLNRVRQQVIQLLSGYQGKEAATAGGPAEGT
PSTSLVLDQFGRNLTQAARESKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVKGEVPETLKD
KHLYTLDLGALVAGSRYRGDFEERLKKVLKEIRTRGDIILFIDELHTLVGAGAAEGAIDAASILKPMLARGELQTIGATT
LDEYRKHLEKDAALERRFQPIQVAEPSLPHTIEILKGLRDRYEAHHRVSITDSALVAAATLADRYISDRFLPDKAIDLID
EAGSRMRIRRMTAPPDLREFDEKIAGVRRDKESAIDSQDFEKAASLRDKEKQLLAAKAKREKEWKAGDMDVVAEVDEELI
AEVLATATGIPVFKLTEEESSRLLRMEDELHKRVIGQKDAIKALSQAIRRTRAGLKDPKRPGGSFIFAGPSGVGKTELSK
TLAEFLFGDEDALISLDMSEFSEKHTVSRLFGSPPGYVGYEEGGQLTEKVRRKPFSVVLFDEVEKAHPDIFNSLLQILED
GRLTDSQGRVVDFKNTVIIMTTNLGTRDISKGFNLGFAAQGDVRTGYERMKAKVNDELKQHFRPEFLNRVDDTVVFHQLT
EDDIIQIVDLMIAKVDERLKDRDMGIELSGEAKSLLAKRGYDPVLGARPLRRTIQREVEDVLSEKILFGELRPGHIVVVD
TEGEGEEKKFTFRGEEKSALPDVPPIEQAAGGPGPNLSKDA

Nucleotide

• Length: 2526 bp

>NTDB_id=833083 I3F59_RS23620 WP_240134259.1 5383546..5386071(-) (clpC) [Streptomyces sp. MUM 178J]
ATGTTCGAGAGGTTCACCGACCGCGCGCGGCGGGTTGTCGTCCTGGCTCAGGAAGAAGCCCGGATGCTCAACCACAACTA
CATCGGCACCGAGCACATCCTCCTGGGCCTGATCCACGAGGGTGAAGGTGTCGCCGCTAAGGCCCTGGAGAGCCTCGGGA
TTTCGCTCGAGGCGGTCCGCCAGCAGGTGGAGGAGATCATCGGCCAGGGCCAGCAGGCCCCGTCCGGGCACATCCCCTTC
ACTCCCCGTGCCAAGAAGGTCCTGGAGCTGTCGCTCCGCGAGGCCCTTCAGCTGGGCCACAACTACATCGGCACGGAGCA
CATCCTGCTGGGCCTGATCCGTGAGGGCGAGGGCGTGGCCGCCCAGGTCCTTGTGAAGCTCGGCGCCGATCTCAACCGGG
TGCGGCAGCAGGTCATCCAGCTGCTCTCCGGTTACCAGGGCAAGGAAGCCGCCACCGCGGGCGGCCCGGCCGAGGGCACG
CCCTCGACCTCCCTCGTCCTCGACCAGTTCGGCCGGAATCTCACCCAGGCCGCACGGGAGTCCAAGCTCGACCCGGTCAT
CGGGCGCGAGAAGGAAATCGAGCGGGTCATGCAGGTGCTGTCCCGCCGCACCAAGAACAACCCGGTCCTCATCGGCGAGC
CCGGCGTCGGCAAGACCGCCGTCGTCGAGGGGCTGGCGCAGGCCATCGTCAAGGGCGAGGTGCCCGAGACCCTCAAGGAC
AAGCACCTCTACACCCTCGACCTGGGCGCACTGGTCGCCGGCTCCCGCTACCGCGGCGACTTCGAGGAGCGCCTGAAGAA
GGTCCTCAAGGAGATCCGCACCCGCGGCGACATCATCCTGTTCATCGACGAGCTCCACACCCTGGTGGGTGCGGGCGCCG
CCGAGGGCGCGATCGACGCCGCGAGCATCCTGAAGCCCATGTTGGCCCGCGGCGAGCTGCAGACCATCGGTGCGACGACG
CTCGACGAGTACCGCAAGCACCTGGAGAAGGACGCCGCGCTGGAGCGCCGCTTCCAGCCCATCCAGGTCGCGGAGCCGTC
GCTGCCGCACACGATCGAGATCCTCAAGGGTCTGCGCGACCGCTACGAGGCCCACCACCGCGTCTCCATCACCGACTCCG
CGCTGGTCGCCGCCGCGACGCTGGCCGACCGGTACATCTCGGACCGCTTCCTGCCGGACAAGGCGATCGACCTGATCGAC
GAGGCCGGCTCCCGGATGCGCATCCGCCGGATGACCGCGCCGCCGGACCTGCGCGAGTTCGACGAGAAGATCGCAGGCGT
CCGCCGCGACAAGGAGTCCGCGATCGACTCGCAGGACTTCGAGAAGGCCGCCTCGCTGCGCGACAAGGAGAAGCAGCTCC
TTGCCGCCAAGGCGAAGCGCGAGAAGGAGTGGAAGGCCGGCGACATGGACGTCGTCGCCGAGGTGGACGAGGAGCTGATC
GCCGAGGTCCTGGCCACCGCCACCGGCATCCCGGTCTTCAAGCTCACCGAGGAGGAGTCCTCCCGGCTGCTGCGCATGGA
GGACGAGCTCCACAAGCGCGTCATCGGCCAGAAGGACGCCATCAAGGCGCTCTCGCAGGCCATCCGCCGTACCCGCGCCG
GCCTGAAGGACCCGAAGCGCCCCGGCGGCTCGTTCATCTTCGCCGGCCCGTCCGGCGTCGGTAAGACCGAGCTGTCCAAG
ACGCTCGCCGAGTTCCTCTTCGGCGACGAGGACGCGCTGATCTCCCTCGACATGTCGGAGTTCAGCGAGAAGCACACGGT
GTCGCGCCTCTTCGGCTCCCCGCCCGGATACGTGGGCTATGAAGAGGGCGGCCAGCTCACCGAGAAGGTGCGCCGCAAGC
CGTTCTCCGTCGTCCTCTTCGACGAGGTGGAGAAGGCCCACCCGGACATCTTCAACTCGCTGCTGCAGATCCTGGAGGAC
GGTCGGCTGACCGACTCCCAGGGCCGGGTCGTGGACTTCAAGAACACGGTCATCATCATGACCACCAACCTCGGCACCCG
GGACATCTCCAAGGGCTTCAACCTGGGCTTCGCCGCCCAGGGCGACGTCAGGACCGGCTACGAGCGGATGAAGGCGAAGG
TCAACGATGAGCTGAAGCAGCACTTCCGGCCCGAGTTCCTCAACCGTGTGGACGACACGGTCGTCTTCCACCAGCTCACC
GAGGACGACATCATCCAGATCGTCGACCTCATGATCGCCAAGGTGGACGAGCGGCTGAAGGACCGCGACATGGGCATCGA
GCTGAGCGGTGAGGCGAAGTCCCTCCTCGCCAAGCGCGGCTACGACCCGGTCCTGGGCGCCCGCCCGCTGCGCCGCACGA
TCCAGCGCGAGGTCGAGGACGTGCTCTCCGAGAAGATCCTCTTCGGCGAGCTGCGCCCCGGTCACATCGTGGTCGTGGAC
ACCGAGGGCGAGGGTGAGGAGAAGAAGTTCACCTTCCGCGGCGAGGAGAAGTCGGCGCTTCCCGACGTCCCGCCGATCGA
GCAGGCAGCGGGCGGCCCTGGCCCGAACCTCTCGAAGGACGCGTGA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (719-799)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (93-142)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (16-68)

• ATPase family associated with various cellular activities (AAA) (AAA) (209-329)

• AAA lid domain (AAA_lid_9) (349-449)

• AAA domain (Cdc48 subfamily) (AAA_2) (541-712)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	61.596	95.363	0.587
clpC	Streptococcus mutans UA159	44.458	98.692	0.439
clpC	Streptococcus thermophilus LMD-9	43.095	99.881	0.43
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	44.074	96.314	0.424
clpC	Streptococcus pneumoniae D39	44.458	95.482	0.424
clpC	Streptococcus pneumoniae Rx1	44.458	95.482	0.424
clpC	Streptococcus pneumoniae TIGR4	44.486	94.887	0.422
clpE	Streptococcus mutans UA159	53.674	74.435	0.4
clpE	Streptococcus pneumoniae TIGR4	52.809	74.078	0.391
clpE	Streptococcus pneumoniae Rx1	52.809	74.078	0.391
clpE	Streptococcus pneumoniae D39	52.809	74.078	0.391
clpE	Streptococcus pneumoniae R6	52.809	74.078	0.391
clpC	Streptococcus thermophilus LMG 18311	49.028	79.548	0.39
clpC	Lactococcus lactis subsp. cremoris KW2	51.613	73.722	0.381