Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   I3F59_RS13595 Genome accession   NZ_CP140097
Coordinates   3106432..3107124 (-) Length   230 a.a.
NCBI ID   WP_240135085.1    Uniprot ID   -
Organism   Streptomyces sp. MUM 178J     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3101432..3112124
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I3F59_RS13570 (I3F59_013570) - 3101737..3102156 (-) 420 WP_240135090.1 hypothetical protein -
  I3F59_RS13575 (I3F59_013575) - 3102153..3103673 (-) 1521 WP_240135089.1 recombinase family protein -
  I3F59_RS13580 (I3F59_013580) - 3103891..3104493 (-) 603 WP_240135088.1 hypothetical protein -
  I3F59_RS13585 (I3F59_013585) - 3105012..3105818 (+) 807 WP_240135087.1 hypothetical protein -
  I3F59_RS13590 (I3F59_013590) - 3105955..3106386 (-) 432 WP_240135086.1 PaaI family thioesterase -
  I3F59_RS13595 (I3F59_013595) vraR 3106432..3107124 (-) 693 WP_240135085.1 response regulator transcription factor Regulator
  I3F59_RS13600 (I3F59_013600) - 3107121..3108383 (-) 1263 WP_240135084.1 histidine kinase -
  I3F59_RS13605 (I3F59_013605) - 3108623..3108763 (+) 141 Protein_2679 GNAT family N-acetyltransferase -
  I3F59_RS13610 (I3F59_013610) - 3109185..3109808 (+) 624 WP_240135083.1 TetR/AcrR family transcriptional regulator -
  I3F59_RS13615 (I3F59_013615) - 3109808..3110722 (+) 915 WP_240135082.1 hypothetical protein -
  I3F59_RS13620 (I3F59_013620) - 3110765..3110836 (+) 72 Protein_2682 DDE endonuclease -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 24611.28 Da        Isoelectric Point: 5.1676

>NTDB_id=833055 I3F59_RS13595 WP_240135085.1 3106432..3107124(-) (vraR) [Streptomyces sp. MUM 178J]
MTAQTTPPIRLLIVDDDPLVRAGLSLMLGGADGIEIVGEGADGAEVPALVEERTPDVVLMDIRMPTVDGLTATEELRRRP
KAPEVVVLTTFHADRHVLRALRAGAAGFVLKDTPPGQIVDAVRKVAAGEPVLSPAVTRQLMTHVADSAGDERALRARARL
DTLAEREHEVAVAVGHGRSNAEIAAELYMSVPTVKAHVSRILAKLELNNRVQIALLVHDAGLLDEDEPRP

Nucleotide


Download         Length: 693 bp        

>NTDB_id=833055 I3F59_RS13595 WP_240135085.1 3106432..3107124(-) (vraR) [Streptomyces sp. MUM 178J]
ATGACCGCTCAGACCACCCCTCCCATCCGGCTGCTCATCGTCGACGACGACCCCCTCGTACGGGCCGGACTCTCCCTGAT
GCTCGGCGGCGCCGACGGCATCGAGATCGTGGGGGAGGGGGCCGACGGGGCGGAGGTCCCCGCGCTCGTCGAGGAACGGA
CGCCCGACGTGGTGCTGATGGACATCCGGATGCCGACAGTGGACGGCCTGACCGCCACCGAGGAACTGCGCCGCAGGCCG
AAGGCGCCCGAAGTGGTGGTCCTCACCACCTTCCACGCCGATCGACACGTGCTCCGGGCACTGCGCGCCGGGGCCGCCGG
GTTCGTCCTCAAGGACACTCCGCCCGGGCAGATCGTCGACGCGGTCCGGAAGGTCGCGGCGGGAGAGCCGGTGCTCTCCC
CGGCCGTCACCCGGCAGCTGATGACCCATGTCGCCGACAGCGCGGGCGACGAGCGCGCCCTCCGCGCACGGGCGCGGCTG
GACACGCTCGCCGAACGTGAACACGAGGTGGCCGTCGCCGTCGGCCATGGCCGCTCCAATGCGGAGATCGCCGCGGAGCT
CTATATGAGCGTCCCCACCGTCAAGGCACATGTCTCCCGCATCCTGGCCAAGCTCGAGCTCAACAACCGGGTGCAGATCG
CGCTGCTGGTGCATGACGCGGGGCTGCTCGACGAGGACGAGCCAAGGCCATAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(12-122)

Bacterial regulatory proteins, luxR family (GerE)

(162-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.71

94.348

0.365