Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   QM317_RS00725 Genome accession   NZ_CP125861
Coordinates   175275..175949 (+) Length   224 a.a.
NCBI ID   WP_000866106.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 12-03119     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 171523..186776 175275..175949 within 0


Gene organization within MGE regions


Location: 171523..186776
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QM317_RS00710 (QM317_00710) - 171523..172422 (-) 900 WP_000196697.1 Mph(C) family macrolide 2'-phosphotransferase -
  QM317_RS00715 (QM317_00715) msr(A) 172521..173987 (-) 1467 WP_000438874.1 ABC-F type ribosomal protection protein Msr(A) -
  QM317_RS00720 (QM317_00720) - 174461..175135 (+) 675 WP_001105960.1 IS6 family transposase -
  QM317_RS00725 (QM317_00725) braR 175275..175949 (+) 675 WP_000866106.1 response regulator transcription factor Regulator
  QM317_RS00730 (QM317_00730) - 175946..176827 (+) 882 Protein_144 sensor histidine kinase -
  QM317_RS00735 (QM317_00735) - 176943..177872 (+) 930 WP_000793446.1 ABC transporter ATP-binding protein -
  QM317_RS00740 (QM317_00740) - 177865..178602 (+) 738 WP_000369394.1 ABC transporter permease -
  QM317_RS00745 (QM317_00745) - 178616..178792 (+) 177 Protein_147 undecaprenyl-diphosphate phosphatase -
  QM317_RS00750 (QM317_00750) - 178849..179523 (+) 675 WP_001105960.1 IS6 family transposase -
  QM317_RS00755 (QM317_00755) - 179664..180299 (+) 636 Protein_149 aminoglycoside 6-adenylyltransferase -
  QM317_RS00760 (QM317_00760) sat4 180296..180831 (+) 536 Protein_150 streptothricin N-acetyltransferase Sat4 -
  QM317_RS00765 (QM317_00765) aph(3')-IIIa 180924..181718 (+) 795 WP_001096887.1 aminoglycoside O-phosphotransferase APH(3')-IIIa -
  QM317_RS00770 (QM317_00770) - 181951..182625 (-) 675 WP_001105987.1 IS6-like element IS257 family transposase -
  QM317_RS00775 (QM317_00775) - 182730..183725 (+) 996 WP_001199887.1 protein rep -
  QM317_RS00780 (QM317_00780) cadD 184888..185505 (+) 618 WP_000616816.1 cadmium resistance transporter CadD -
  QM317_RS00785 (QM317_00785) - 185524..185871 (+) 348 WP_000119690.1 metalloregulator ArsR/SmtB family transcription factor -
  QM317_RS00790 (QM317_00790) - 186102..186776 (-) 675 WP_001105987.1 IS6-like element IS257 family transposase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25839.93 Da        Isoelectric Point: 4.9884

>NTDB_id=833045 QM317_RS00725 WP_000866106.1 175275..175949(+) (braR) [Staphylococcus aureus strain 12-03119]
MKVLIVEDDLVIGKMLAEELKKWQLEPILIEGFNHVMDAFNTNAPELVLLDINLPAFNGYHWCQEIRKVSTVPIIFISSR
NDSMDQVMAMQMGADDFIEKPFNMTVTITKIQALLRRTYDFTTQVNNLTVDDCELLLDAAKLKFNEETIDLTHTELQIMH
SLFQNKGKFVSRNALIEKCWESEHFIDDNTLAVNITRLRKKLQKLGLTDFIETKKNVGYRVGDV

Nucleotide


Download         Length: 675 bp        

>NTDB_id=833045 QM317_RS00725 WP_000866106.1 175275..175949(+) (braR) [Staphylococcus aureus strain 12-03119]
ATGAAAGTATTAATCGTAGAGGATGACTTAGTTATCGGGAAGATGCTTGCTGAAGAGCTCAAGAAGTGGCAGCTAGAACC
GATCTTAATAGAAGGTTTCAATCATGTAATGGATGCCTTCAACACGAATGCACCGGAACTTGTGTTACTCGATATTAATT
TACCTGCCTTCAATGGTTATCACTGGTGTCAGGAGATTCGTAAAGTTTCTACTGTACCGATTATATTTATTAGTTCGCGT
AACGACAGTATGGATCAAGTAATGGCGATGCAGATGGGTGCGGATGATTTCATTGAGAAGCCATTTAATATGACTGTTAC
AATTACTAAGATTCAAGCACTATTACGCCGCACGTATGATTTCACCACTCAAGTTAATAATTTAACAGTAGATGATTGCG
AGTTACTACTTGATGCAGCAAAGCTTAAATTTAATGAAGAAACCATAGACCTGACACACACTGAATTGCAAATCATGCAT
AGCTTATTCCAGAACAAGGGCAAATTCGTCAGTCGTAATGCGTTAATCGAAAAATGCTGGGAATCAGAACACTTCATTGA
TGACAATACGCTTGCTGTCAACATTACACGTTTACGCAAAAAGCTACAAAAACTAGGACTTACAGATTTTATCGAAACGA
AGAAAAATGTCGGATATCGTGTAGGTGACGTATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

66.516

98.661

0.656