Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   I3F59_RS05420 Genome accession   NZ_CP140097
Coordinates   1227065..1230109 (-) Length   1014 a.a.
NCBI ID   WP_240135890.1    Uniprot ID   -
Organism   Streptomyces sp. MUM 178J     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1222065..1235109
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I3F59_RS05405 (I3F59_005405) uvrC 1222999..1225101 (-) 2103 WP_240135887.1 excinuclease ABC subunit UvrC -
  I3F59_RS05410 (I3F59_005410) - 1225475..1225903 (-) 429 WP_240135888.1 Rieske (2Fe-2S) protein -
  I3F59_RS05415 (I3F59_005415) - 1226105..1227013 (+) 909 WP_240135889.1 carbohydrate kinase -
  I3F59_RS05420 (I3F59_005420) uvrA 1227065..1230109 (-) 3045 WP_240135890.1 excinuclease ABC subunit UvrA Machinery gene
  I3F59_RS05425 (I3F59_005425) - 1230304..1230990 (+) 687 WP_240135891.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  I3F59_RS05430 (I3F59_005430) - 1231231..1231887 (+) 657 WP_240135892.1 MBL fold metallo-hydrolase -
  I3F59_RS05435 (I3F59_005435) - 1231910..1232650 (-) 741 WP_240135893.1 alpha/beta fold hydrolase -
  I3F59_RS05440 (I3F59_005440) - 1232779..1233768 (-) 990 WP_240135894.1 TerC family protein -

Sequence

Protein


Download         Length: 1014 a.a.        Molecular weight: 111185.53 Da        Isoelectric Point: 8.3401

>NTDB_id=833039 I3F59_RS05420 WP_240135890.1 1227065..1230109(-) (uvrA) [Streptomyces sp. MUM 178J]
MADRLIVRGAREHNLKNVSLDLPRDSLIVFTGLSGSGKSSLAFDTIFAEGQRRYVESLSSYARQFLGQMDKPDVDFIEGL
SPAVSIDQKSTSRNPRSTVGTITEVYDYLRLLFARIGKPHCPQCGRPISRQSPQAIVDKVLELPEGSRFQVLSPLVRERK
GEFVDLFSDLQTKGYSRARVDGQTVQLADPPKLKKQEKHTIEVVVDRLTVKDSAKRRLTDSVETALGLSGGMVVLDFVDL
PEDDPERERMYSEHLYCAYDDLSFEELEPRSFSFNSPFGACPDCTGIGTRMEVDPELIVPDPDRSLDEGAIHPWSHGHTK
EYFGRLIGGLALALGFSTDMPWAGLPQRAKKALLHGHKTQVEVRYRNRYGRERAYTTPAFEGAVQFVKRRHSEAESDSSR
ERFEGYMREVPCPTCEGSRLKPIVLAVTVMEKSIADVSAMSISECADFLGRLKLNARDKKIAERVLKEVNERLRFLVDVG
LDYLSLNRAAGTLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNHRLIETLVRLRDMGNTLIVVEHDEDTIKVA
DWVVDIGPGAGEHGGKVVHSGPLAELVSNKESMTGQYLSRKRAIATPDVRRPVDPARRLTVHGARENNLRDIDVSFPLGV
LTAVTGVSGSGKSTLVNDILYTHLARELNGAKSVPGRHTRVAGDDLVDKVVHVDQSPIGRTPRSNPATYTGVFDHVRKLF
AETMEAKVRGYLPGRFSFNVKGGRCENCSGDGTIKIEMNFLPDVYVPCEVCHGARYNRETLEVHYKGKSIAEVLDMPIEE
ALHFFEAVPTISRHLKTLTEVGLGYVRLGQPAPTLSGGEAQRVKLASELQKRSTGRTVYVLDEPTTGLHFEDINKLINVL
SGLVDKGNTVIVIEHNLDVIKTADWVLDLGPEGGSGGGLVIAEGTPEQVAGVPASHTGKFLREILDAERISDAVPPPRSA
RKAAQKKAAAKTAAANATGAEKTAAVSRKPAKTVAAKSTAAKKTATARTRTRKG

Nucleotide


Download         Length: 3045 bp        

>NTDB_id=833039 I3F59_RS05420 WP_240135890.1 1227065..1230109(-) (uvrA) [Streptomyces sp. MUM 178J]
GTGGCCGACCGTCTCATCGTCCGTGGCGCTCGCGAGCACAACCTGAAGAACGTCTCGCTCGACCTCCCGCGTGACTCCCT
CATCGTCTTCACCGGGCTCTCGGGGTCGGGCAAGTCGTCGCTCGCGTTCGACACGATCTTCGCCGAGGGACAGCGCCGCT
ATGTCGAATCCCTCTCCTCCTACGCCCGGCAGTTCCTCGGCCAGATGGACAAGCCGGACGTCGACTTCATCGAGGGACTC
TCCCCGGCCGTCTCCATCGACCAGAAGTCCACGTCGCGCAACCCGCGCTCGACGGTGGGCACCATCACCGAGGTCTACGA
CTACCTCCGGCTGCTCTTCGCCCGGATCGGCAAGCCGCACTGCCCCCAGTGCGGCCGGCCCATCTCGCGCCAGTCGCCGC
AGGCCATCGTGGACAAGGTCCTGGAGCTGCCCGAGGGCAGCCGCTTCCAGGTCCTCTCGCCCCTGGTCCGGGAGCGCAAG
GGGGAGTTCGTCGATCTCTTCTCCGATCTGCAGACGAAGGGATACAGCCGGGCGCGTGTCGACGGACAGACCGTCCAGCT
CGCCGATCCGCCCAAGCTCAAGAAGCAGGAGAAGCACACCATCGAGGTGGTCGTCGACCGCCTCACGGTCAAGGACTCCG
CCAAGCGCCGGCTCACCGACTCCGTGGAGACCGCGCTGGGCCTCTCCGGCGGCATGGTCGTGCTCGACTTCGTCGACCTC
CCAGAGGACGACCCCGAGCGGGAGCGGATGTACTCGGAGCATCTGTACTGCGCCTACGACGACCTGTCCTTCGAGGAGCT
GGAGCCCCGCTCGTTCTCCTTCAACTCCCCCTTCGGCGCCTGCCCCGACTGCACCGGCATCGGCACCCGTATGGAGGTCG
ACCCCGAGCTGATCGTGCCCGACCCGGACAGGTCCCTGGACGAAGGCGCGATCCACCCCTGGTCCCATGGCCACACCAAG
GAGTACTTCGGCCGGCTGATCGGCGGACTCGCCCTTGCCCTGGGCTTCTCCACCGACATGCCCTGGGCCGGTCTGCCGCA
GCGTGCCAAGAAGGCTCTGCTGCACGGGCACAAGACACAGGTCGAGGTCCGCTACCGCAATCGGTACGGGAGGGAGCGCG
CCTACACCACGCCCGCCTTCGAAGGGGCGGTGCAGTTCGTCAAGCGACGGCACTCCGAGGCCGAGAGCGACTCCAGCAGG
GAGCGCTTCGAGGGTTATATGCGCGAGGTGCCCTGCCCCACCTGCGAGGGCTCCCGGCTCAAGCCGATCGTCTTGGCGGT
CACGGTCATGGAGAAGTCCATTGCCGATGTCTCGGCCATGTCGATCAGCGAGTGCGCCGACTTCCTCGGCCGGCTGAAGC
TGAACGCCCGCGACAAGAAGATCGCGGAGCGAGTGCTCAAGGAGGTCAACGAACGGCTGAGGTTCCTGGTCGACGTCGGC
CTGGACTATCTCTCGCTCAACCGCGCGGCGGGCACCCTGTCCGGCGGAGAGGCCCAGCGCATCCGGCTGGCCACCCAGAT
CGGCTCCGGTCTGGTCGGCGTGCTCTACGTCCTCGACGAGCCCTCCATCGGGCTGCACCAGCGTGACAACCACCGACTGA
TCGAGACCCTGGTGCGGCTGCGCGACATGGGCAACACGCTCATCGTCGTCGAGCACGACGAGGACACCATCAAGGTGGCC
GACTGGGTGGTCGACATCGGCCCGGGCGCGGGCGAGCACGGCGGCAAGGTGGTCCACTCGGGCCCGCTGGCGGAGCTGGT
GTCCAACAAGGAGTCGATGACCGGGCAGTACCTCTCCCGCAAGCGGGCCATCGCCACCCCCGACGTCCGCAGGCCCGTCG
ACCCGGCACGCCGGCTCACCGTCCACGGCGCCCGGGAGAACAACCTGCGGGACATCGACGTGTCCTTCCCGCTCGGGGTG
CTCACCGCCGTCACCGGAGTCTCCGGGTCCGGGAAGTCGACCCTGGTCAACGACATCCTCTACACCCACCTCGCCCGCGA
GCTGAACGGCGCGAAGTCGGTGCCGGGGCGCCACACGCGCGTAGCGGGCGACGATCTCGTCGACAAGGTGGTGCACGTCG
ACCAGTCGCCCATCGGCCGGACCCCCCGCTCCAACCCGGCCACCTACACCGGCGTCTTCGACCATGTGCGCAAGCTCTTC
GCCGAGACGATGGAGGCGAAGGTCCGCGGCTACCTCCCCGGCCGGTTCTCCTTCAACGTCAAGGGCGGCCGCTGTGAGAA
CTGCTCCGGCGACGGCACCATCAAGATCGAGATGAACTTCCTGCCGGATGTGTATGTGCCGTGCGAGGTCTGCCACGGAG
CGCGCTACAACCGGGAGACGCTGGAGGTCCACTACAAGGGCAAGTCCATCGCCGAGGTGCTGGACATGCCGATCGAGGAG
GCCCTGCACTTCTTCGAGGCCGTTCCCACGATCTCGCGGCACCTCAAGACCCTCACCGAGGTCGGACTGGGCTATGTGCG
GCTCGGACAGCCCGCGCCGACGCTCTCCGGCGGCGAGGCGCAGCGGGTGAAGCTGGCCTCGGAGCTCCAGAAGCGCTCCA
CGGGCCGCACGGTCTATGTGCTGGACGAGCCGACCACCGGCCTGCACTTCGAGGACATCAACAAGCTGATCAATGTGCTC
TCCGGCCTGGTGGACAAGGGCAACACCGTGATCGTCATCGAGCACAATCTGGATGTCATCAAGACGGCGGACTGGGTGCT
CGACCTGGGCCCCGAGGGGGGCAGCGGCGGCGGACTGGTGATCGCCGAAGGCACTCCGGAGCAGGTCGCCGGCGTGCCGG
CCAGCCACACCGGAAAGTTCCTCAGGGAGATCCTGGACGCCGAGCGGATCAGCGACGCGGTGCCGCCCCCGCGCAGTGCG
AGGAAGGCCGCGCAGAAGAAGGCCGCGGCCAAGACCGCCGCTGCGAACGCGACCGGCGCCGAGAAGACGGCCGCTGTCAG
CAGGAAGCCCGCCAAGACGGTCGCGGCCAAGAGCACGGCGGCCAAGAAGACGGCCACGGCGCGGACCCGTACCCGCAAGG
GCTGA

Domains

Predicted by InterProScan.

UvrA DNA-binding domain (UvrA_DNA-bind)

(294-404)

UvrA interaction domain (UvrA_inter)

(131-238)

ABC transporter (ABC_tran)

(629-865)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

55.987

93.886

0.526
  uvrA Streptococcus pneumoniae TIGR4

55.987

93.886

0.526
  uvrA Streptococcus pneumoniae D39

55.987

93.886

0.526