Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   ULK21_RS18705 Genome accession   NZ_CP139887
Coordinates   3840130..3840570 (+) Length   146 a.a.
NCBI ID   WP_000360914.1    Uniprot ID   A0A0H2YVZ3
Organism   Escherichia coli strain ECO21     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 3835130..3845570
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ULK21_RS18685 (ULK21_18680) aroP 3836130..3837500 (+) 1371 WP_000399017.1 aromatic amino acid transporter AroP -
  ULK21_RS18690 (ULK21_18685) ampE 3837543..3838397 (-) 855 WP_000171981.1 beta-lactamase regulator AmpE -
  ULK21_RS18695 (ULK21_18690) ampD 3838394..3838945 (-) 552 WP_000923703.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  ULK21_RS18700 (ULK21_18695) nadC 3839033..3839926 (+) 894 WP_001135168.1 carboxylating nicotinate-nucleotide diphosphorylase -
  ULK21_RS18705 (ULK21_18700) pilA 3840130..3840570 (+) 441 WP_000360914.1 prepilin peptidase-dependent pilin Machinery gene
  ULK21_RS18710 (ULK21_18705) pilB 3840580..3841965 (+) 1386 WP_097478763.1 type II secretion system protein GspE Machinery gene
  ULK21_RS18715 (ULK21_18710) hofC 3841955..3843157 (+) 1203 WP_001523973.1 protein transport protein HofC -
  ULK21_RS18720 (ULK21_18715) guaC 3843192..3844235 (-) 1044 WP_001217320.1 GMP reductase -
  ULK21_RS18725 (ULK21_18720) - 3844391..3844435 (-) 45 WP_120795372.1 protein YacM -
  ULK21_RS18730 (ULK21_18725) coaE 3844460..3845080 (+) 621 WP_001269520.1 dephospho-CoA kinase -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 15620.77 Da        Isoelectric Point: 4.5237

>NTDB_id=832637 ULK21_RS18705 WP_000360914.1 3840130..3840570(+) (pilA) [Escherichia coli strain ECO21]
MDKQRGFTLIELMVVIGIIAILSAIGIPAYQNYLRKAALTDMLQTFVPYRTAVELCALEHGGLNTCDGGSNGIPSPTTTR
YVSAMSVAKGVVSLTGQESLNGLSVVMTPGWDNANGVTGWTRNCNIQSDSALQQACEDVFRFDDAN

Nucleotide


Download         Length: 441 bp        

>NTDB_id=832637 ULK21_RS18705 WP_000360914.1 3840130..3840570(+) (pilA) [Escherichia coli strain ECO21]
ATGGACAAGCAACGCGGTTTTACACTTATCGAACTGATGGTGGTTATTGGCATCATTGCCATTTTAAGCGCCATTGGTAT
TCCCGCTTATCAAAACTACCTGCGCAAAGCCGCACTCACCGACATGCTACAAACCTTTGTGCCTTACCGTACCGCCGTAG
AGTTGTGCGCGCTGGAACATGGTGGATTAAATACCTGCGACGGTGGCAGCAATGGCATTCCTTCGCCTACCACCACCCGC
TATGTTTCAGCCATGAGTGTGGCAAAGGGCGTGGTGTCGCTGACCGGGCAAGAAAGTCTCAATGGGCTAAGCGTCGTCAT
GACACCGGGTTGGGATAACGCAAACGGCGTCACCGGCTGGACGCGTAACTGCAATATTCAAAGTGACAGCGCATTGCAGC
AAGCCTGCGAAGATGTCTTCCGCTTTGATGACGCCAACTAA

Domains

Predicted by InterProScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(1-25)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2YVZ3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Haemophilus influenzae 86-028NP

43.089

84.247

0.363