Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   U0450_RS00345 Genome accession   NZ_CP139863
Coordinates   79335..79799 (-) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus pneumoniae strain 15P2112     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 74335..84799
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0450_RS00325 - 75286..76254 (-) 969 WP_000105360.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  U0450_RS00330 pdrM 76408..77769 (-) 1362 WP_000278537.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  U0450_RS00335 - 77780..78040 (-) 261 WP_001105925.1 hypothetical protein -
  U0450_RS00340 - 78054..79322 (-) 1269 WP_000924492.1 dihydroorotase -
  U0450_RS00345 mutX 79335..79799 (-) 465 WP_001135768.1 8-oxo-dGTP diphosphatase Machinery gene
  U0450_RS00350 - 79809..80462 (-) 654 WP_001809694.1 uracil-DNA glycosylase -
  U0450_RS00355 - 80600..81247 (-) 648 WP_001824648.1 hypothetical protein -
  U0450_RS00360 - 81261..81974 (-) 714 WP_000499436.1 YjjG family noncanonical pyrimidine nucleotidase -
  U0450_RS00365 dhaM 82433..82813 (-) 381 WP_000443784.1 dihydroxyacetone kinase phosphoryl donor subunit DhaM -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=832387 U0450_RS00345 WP_001135768.1 79335..79799(-) (mutX) [Streptococcus pneumoniae strain 15P2112]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=832387 U0450_RS00345 WP_001135768.1 79335..79799(-) (mutX) [Streptococcus pneumoniae strain 15P2112]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGCGCGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGACGCTAGAATGGGTTCC
CTATGACGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCTAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987