Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   U0449_RS03600 Genome accession   NZ_CP139862
Coordinates   718658..720763 (-) Length   701 a.a.
NCBI ID   WP_050207129.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 05H0020-2     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 713658..725763
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0449_RS03580 - 714200..714373 (-) 174 WP_001022229.1 hypothetical protein -
  U0449_RS03585 - 714532..716139 (-) 1608 WP_050218935.1 alpha-glucosidase -
  U0449_RS03590 - 716292..717776 (+) 1485 WP_050218934.1 DUF1846 domain-containing protein -
  U0449_RS03595 - 717871..718362 (+) 492 WP_050218933.1 S-ribosylhomocysteine lyase -
  U0449_RS03600 clpC 718658..720763 (-) 2106 WP_050207129.1 AAA family ATPase Regulator
  U0449_RS03605 mraY 721372..722352 (-) 981 WP_000470829.1 phospho-N-acetylmuramoyl-pentapeptide- transferase -
  U0449_RS03610 pbp2X 722354..724606 (-) 2253 WP_000872269.1 penicillin-binding protein 2X -
  U0449_RS03615 ftsL 724610..724927 (-) 318 WP_000818547.1 cell division protein FtsL -

Sequence

Protein


Download         Length: 701 a.a.        Molecular weight: 77595.37 Da        Isoelectric Point: 4.7351

>NTDB_id=832297 U0449_RS03600 WP_050207129.1 718658..720763(-) (clpC) [Streptococcus pneumoniae strain 05H0020-2]
MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEFAHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLG
RNLTAEAREGKLDPVIGRNKEIQETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQHHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAA
QHPVTDVHAVEREIETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTGIPVSQMGA
SDIERLKDMAHRLQDKVIGQDKAVEVVARAIRRNRAGFDEGNRPIGSFLFVGSTGVGKTELAKQLALDMFGTQDAIIRLD
MSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNT
VIIATSNAGFGHEANLTEDVDKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLAEVNQTLAKKDIDLVVS
QAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLDAKHLEADMEDGVLVIREKA

Nucleotide


Download         Length: 2106 bp        

>NTDB_id=832297 U0449_RS03600 WP_050207129.1 718658..720763(-) (clpC) [Streptococcus pneumoniae strain 05H0020-2]
ATGAATAACAACTTTAATAATTTTAATAACATGGATGATTTATTTAACCAATTGATGGGTGGTATGCGAGGATACAGTTC
TGAAAATCGCCGTTACTTAATTAATGGACGCGAAGTCACACCTGAGGAATTTGCTCACTATCGTGCGACTGGTCAATTAC
CAGGAAATGCAGAAACTGATGTGCAAATGCCACAACAGGCATCAGGTATGAAACAAGACGGTGTCCTTGCAAAACTAGGT
CGAAACTTAACAGCAGAAGCGCGTGAGGGCAAGTTGGATCCTGTTATCGGACGAAACAAGGAAATTCAAGAAACATCTGA
AATCCTCTCACGCCGCACCAAGAACAATCCTGTTTTGGTCGGAGATGCAGGTGTTGGTAAGACAGCAGTTGTCGAAGGTC
TAGCGCAAGCCATTGTGAACGGAGATGTTCCTGCTGCTATCAAGAACAAGGAAATTATTTCTATTGATATCTCAGGTCTT
GAGGCTGGTACTCAATACCGTGGTAGCTTTGAAGAAAATGTCCAAAACTTAGTCAATGAAGTGAAAGAAGCAGGGAATAT
TATCCTCTTCTTTGATGAAATTCACCAAATTCTTGGTGCTGGTAGCACTGGTGGAGACAGTGGTTCTAAAGGGCTTGCGG
ATATTCTCAAGCCAGCTCTCTCTCGTGGAGAATTGACAGTGATTGGGGCAACAACTCAAGACGAATACCGTAACACCATC
TTGAAGAATGCTGCTCTTGCTCGTCGTTTCAACGAAGTGAAGGTCAATGCTCCTTCGGCAGAGAATACTTTTAAAATTCT
TCAAGGAATTCGTGACCTCTATCAACAACACCACAATGTCATCTTGCCAGACGAAGTCTTGAAAGCAGCGGTGGATTATT
CTGTTCAATACATTCCTCAACGTAGCTTGCCAGATAAGGCTATTGACCTTGTCGATGTAACGGCTGCTCACTTGGCGGCT
CAACATCCAGTAACAGATGTGCATGCTGTTGAACGAGAAATCGAAACGGAAAAAGACAAGCAAGAAAAAGCAGTTGAAGC
AGAAGATTTTGAAGCAGCTCTAAACTATAAAACACGCATTGCAGAATTGGAAAAGAAAATCGAAAACCACACAGAAGATA
TGAAAGTGACTGCAAGTGTCAACGATGTGGCTGAATCTGTGGAACGAATGACAGGTATCCCAGTATCGCAAATGGGAGCT
TCAGATATCGAACGTTTGAAAGATATGGCTCATCGCTTGCAAGACAAGGTGATTGGTCAAGATAAGGCCGTAGAAGTTGT
AGCTCGTGCTATCCGTCGTAACCGTGCTGGTTTTGATGAAGGAAATCGCCCAATCGGCAGCTTCCTCTTTGTAGGGTCTA
CTGGGGTTGGTAAGACGGAGCTTGCTAAGCAATTGGCACTCGATATGTTTGGAACCCAGGATGCGATTATCCGTTTGGAT
ATGTCTGAATACAGTGACCGCACAGCTGTTTCTAAGCTAATTGGTACAACAGCAGGCTATGTGGGTTATGATGACAATAG
CAATACCTTAACAGAACGTGTTCGTCGCAATCCATACTCTATCATTCTCTTGGATGAAATTGAAAAGGCTGATCCTCAAG
TTATTACCCTTCTCCTCCAAGTTCTAGATGATGGTCGTTTGACAGATGGTCAAGGAAATACAGTAAACTTCAAGAACACT
GTCATTATTGCGACCTCAAATGCTGGATTTGGCCATGAAGCCAACTTGACAGAAGATGTGGATAAACCAGAATTGATGGA
CCGTTTGAAACCCTTCTTCCGTCCAGAATTCCTCAACCGCTTTAATGCAGTCATCGAGTTCTCACACTTGACTAAGGAAG
ACCTTTCTAAGATTGTAGATTTGATGTTGGCTGAAGTTAACCAAACCTTGGCTAAGAAAGACATTGACTTGGTAGTCAGT
CAAGCGGCTAAAGATTATATCACAGAAGAAGGTTACGACGAAGTCATGGGGGTTCGTCCTCTCCGTCGAGTGGTTGAACA
AGAAATTCGTGATAAGGTGACAGACTTCCACTTGGATCATTTAGATGCTAAACATCTGGAAGCAGATATGGAAGATGGCG
TTTTGGTTATTCGTGAGAAAGCCTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(610-680)

AAA domain (Cdc48 subfamily) (AAA_2)

(443-603)

ATPase family associated with various cellular activities (AAA) (AAA)

(118-250)

AAA lid domain (AAA_lid_9)

(259-354)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. cremoris KW2

50.078

91.441

0.458
  clpE Streptococcus mutans UA159

49.065

91.583

0.449
  clpE Streptococcus pneumoniae TIGR4

47.792

90.442

0.432
  clpE Streptococcus pneumoniae Rx1

47.792

90.442

0.432
  clpE Streptococcus pneumoniae D39

47.792

90.442

0.432
  clpE Streptococcus pneumoniae R6

47.792

90.442

0.432
  clpC Bacillus subtilis subsp. subtilis str. 168

44.615

92.725

0.414
  clpC Streptococcus pneumoniae Rx1

42.654

90.3

0.385
  clpC Streptococcus pneumoniae D39

42.654

90.3

0.385
  clpC Streptococcus pneumoniae TIGR4

42.496

90.3

0.384
  clpC Streptococcus thermophilus LMD-9

42.18

90.3

0.381
  clpC Streptococcus thermophilus LMG 18311

42.022

90.3

0.379
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

42.788

88.017

0.377
  clpC Streptococcus mutans UA159

41.909

88.16

0.369