Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   U0449_RS03395 Genome accession   NZ_CP139862
Coordinates   673527..674159 (-) Length   210 a.a.
NCBI ID   WP_000698433.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 05H0020-2     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 668527..679159
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0449_RS03370 - 668932..670283 (+) 1352 WP_322397977.1 IS3 family transposase -
  U0449_RS03375 cbpF 670411..671434 (-) 1024 Protein_672 choline-binding protein CbpF -
  U0449_RS03380 - 671453..672298 (-) 846 WP_322398087.1 trypsin-like peptidase domain-containing protein -
  U0449_RS03385 - 672757..673362 (-) 606 Protein_674 DNA alkylation repair protein -
  U0449_RS03390 - 673284..673526 (-) 243 Protein_675 DNA alkylation repair protein -
  U0449_RS03395 vraR 673527..674159 (-) 633 WP_000698433.1 response regulator transcription factor Regulator
  U0449_RS03400 - 674173..675168 (-) 996 WP_000743662.1 sensor histidine kinase -
  U0449_RS03405 liaF 675165..675863 (-) 699 WP_001224634.1 cell wall-active antibiotics response protein LiaF -
  U0449_RS03410 fni 675941..676951 (-) 1011 WP_050104669.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  U0449_RS03415 - 676935..677942 (-) 1008 WP_000562436.1 phosphomevalonate kinase -
  U0449_RS03420 mvaD 677929..678882 (-) 954 WP_000373460.1 diphosphomevalonate decarboxylase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23539.00 Da        Isoelectric Point: 4.5739

>NTDB_id=832293 U0449_RS03395 WP_000698433.1 673527..674159(-) (vraR) [Streptococcus pneumoniae strain 05H0020-2]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQDEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=832293 U0449_RS03395 WP_000698433.1 673527..674159(-) (vraR) [Streptococcus pneumoniae strain 05H0020-2]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGTTTGGGTTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAACATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTGGGGCAAGATGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41