Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   U0447_RS10125 Genome accession   NZ_CP139861
Coordinates   1949361..1949825 (+) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus pneumoniae strain 16H2017-2     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1944361..1954825
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0447_RS10100 - 1946515..1946589 (+) 75 Protein_1943 dihydroxyacetone kinase subunit L -
  U0447_RS10105 - 1946589..1946696 (+) 108 Protein_1944 hypothetical protein -
  U0447_RS10110 - 1947186..1947899 (+) 714 WP_000499437.1 YjjG family noncanonical pyrimidine nucleotidase -
  U0447_RS10115 - 1947913..1948560 (+) 648 WP_001809355.1 hypothetical protein -
  U0447_RS10120 - 1948698..1949351 (+) 654 WP_000401329.1 uracil-DNA glycosylase -
  U0447_RS10125 mutX 1949361..1949825 (+) 465 WP_001135768.1 8-oxo-dGTP diphosphatase Machinery gene
  U0447_RS10130 - 1949838..1951106 (+) 1269 WP_000924489.1 dihydroorotase -
  U0447_RS10135 - 1951120..1951380 (+) 261 WP_001105925.1 hypothetical protein -
  U0447_RS10140 pdrM 1951391..1952752 (+) 1362 WP_000278534.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  U0447_RS10145 - 1952906..1953874 (+) 969 WP_000105360.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=832257 U0447_RS10125 WP_001135768.1 1949361..1949825(+) (mutX) [Streptococcus pneumoniae strain 16H2017-2]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=832257 U0447_RS10125 WP_001135768.1 1949361..1949825(+) (mutX) [Streptococcus pneumoniae strain 16H2017-2]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGCGCGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGACGCTAGAATGGGTTCC
CTATGATGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987