Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   U0447_RS07375 Genome accession   NZ_CP139861
Coordinates   1406680..1407312 (+) Length   210 a.a.
NCBI ID   WP_000698433.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16H2017-2     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1401680..1412312
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0447_RS07350 mvaD 1401957..1402910 (+) 954 WP_000373456.1 diphosphomevalonate decarboxylase -
  U0447_RS07355 - 1402897..1403904 (+) 1008 WP_000562378.1 phosphomevalonate kinase -
  U0447_RS07360 fni 1403888..1404898 (+) 1011 WP_000210613.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  U0447_RS07365 liaF 1404976..1405674 (+) 699 WP_001224640.1 cell wall-active antibiotics response protein LiaF -
  U0447_RS07370 - 1405671..1406666 (+) 996 WP_000743685.1 sensor histidine kinase -
  U0447_RS07375 vraR 1406680..1407312 (+) 633 WP_000698433.1 response regulator transcription factor Regulator
  U0447_RS07380 - 1407313..1407555 (+) 243 Protein_1403 DNA alkylation repair protein -
  U0447_RS07385 - 1407480..1408082 (+) 603 Protein_1404 DNA alkylation repair protein -
  U0447_RS07390 - 1408541..1409143 (+) 603 Protein_1405 trypsin-like serine peptidase -
  U0447_RS07395 - 1409445..1409804 (+) 360 WP_000378122.1 tyrosine-type recombinase/integrase -
  U0447_RS07400 tig 1409998..1411281 (+) 1284 WP_000116473.1 trigger factor -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23539.00 Da        Isoelectric Point: 4.5739

>NTDB_id=832233 U0447_RS07375 WP_000698433.1 1406680..1407312(+) (vraR) [Streptococcus pneumoniae strain 16H2017-2]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQDEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=832233 U0447_RS07375 WP_000698433.1 1406680..1407312(+) (vraR) [Streptococcus pneumoniae strain 16H2017-2]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGTTTGGGTTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAACATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTGGGGCAAGATGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41