Detailed information NTG0832111

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: U0448_RS06940
• Genome accession: NZ_CP139860
• Coordinates: 1341397..1343502 (+)
• Length: 701 a.a.
• NCBI ID: WP_219576785.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 21011
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1336397..1348502

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U0448_RS06925	ftsL	1337233..1337550 (+)	318	WP_000818547.1	cell division protein FtsL	-
U0448_RS06930	pbp2X	1337554..1339806 (+)	2253	WP_219572572.1	penicillin-binding protein PBP2X	-
U0448_RS06935	mraY	1339808..1340788 (+)	981	WP_000470829.1	phospho-N-acetylmuramoyl-pentapeptide- transferase	-
U0448_RS06940	clpC	1341397..1343502 (+)	2106	WP_219576785.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
U0448_RS06945	-	1343908..1344243 (+)	336	Protein_1321	group II intron maturase-specific domain-containing protein	-
U0448_RS06950	-	1344310..1344792 (-)	483	WP_000032550.1	S-ribosylhomocysteine lyase	-
U0448_RS06955	-	1344887..1346371 (-)	1485	WP_219576784.1	DUF1846 domain-containing protein	-
U0448_RS06960	-	1346524..1348131 (+)	1608	WP_001156837.1	alpha-glucosidase	-
U0448_RS06965	-	1348290..1348463 (+)	174	WP_001022229.1	hypothetical protein	-

Sequence

Protein

• Length: 701 a.a.
• Molecular weight: 77613.38 Da
• Isoelectric Point: 4.7068

>NTDB_id=832111 U0448_RS06940 WP_219576785.1 1341397..1343502(+) (clpC) [Streptococcus pneumoniae strain 21011]
MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEFAHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLG
RNLTAEAREGKLDPVIGRNKEIQETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISDL
EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQHHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAA
QHPVTDVHAVEREIETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTGIPVSQMGA
SDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGSTGVGKTELAKQLALDMFGTQDAIIRLD
MSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNT
VIIATSNAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSQLTKEDLSKIVDLMLAEVNQTLAKKDIDLVVS
QAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLDAKHLEADMKDGVLVIREKA

Nucleotide

• Length: 2106 bp

>NTDB_id=832111 U0448_RS06940 WP_219576785.1 1341397..1343502(+) (clpC) [Streptococcus pneumoniae strain 21011]
ATGAATAACAACTTTAATAATTTTAATAACATGGATGATTTATTTAACCAATTGATGGGTGGTATGCGAGGATATAGTTC
TGAAAATCGCCGTTACTTAATTAATGGACGCGAAGTCACACCTGAGGAATTTGCTCACTATCGTGCGACTGGTCAATTAC
CAGGAAATGCAGAAACTGATGTGCAAATGCCACAACAGGCATCAGGTATGAAACAAGACGGTGTCCTTGCAAAACTAGGT
CGAAACTTGACAGCAGAAGCGCGTGAGGGCAAGTTGGATCCTGTTATCGGACGAAACAAGGAAATTCAAGAAACATCTGA
AATCCTCTCACGCCGCACCAAGAACAATCCTGTTTTGGTCGGAGATGCAGGTGTTGGTAAGACAGCAGTTGTCGAAGGTC
TAGCGCAAGCCATTGTGAACGGAGATGTTCCTGCTGCTATCAAGAACAAGGAAATTATTTCTATTGATATCTCAGATCTT
GAGGCTGGTACTCAATACCGTGGTAGCTTTGAAGAAAATGTCCAAAACTTAGTCAATGAAGTGAAAGAAGCAGGGAATAT
TATCCTCTTCTTTGATGAAATTCACCAAATTCTTGGTGCTGGTAGCACTGGTGGAGACAGTGGTTCTAAAGGACTTGCGG
ATATTCTCAAGCCAGCTCTCTCTCGTGGAGAATTGACAGTGATTGGGGCAACAACTCAAGACGAATACCGTAACACCATC
TTGAAGAATGCTGCTCTTGCTCGTCGTTTCAACGAAGTGAAGGTCAATGCTCCTTCAGCAGAGAATACTTTTAAAATTCT
TCAAGGCATTCGTGACCTCTATCAACAACATCACAATGTCATCTTGCCAGACGAAGTCTTGAAAGCAGCGGTGGATTATT
CTGTTCAATACATTCCTCAACGTAGCTTGCCAGATAAGGCTATTGACCTTGTCGATGTAACAGCTGCTCACTTGGCGGCT
CAACATCCAGTAACAGATGTGCATGCTGTTGAACGAGAAATCGAAACGGAAAAAGACAAGCAAGAAAAAGCAGTTGAAGC
AGAAGATTTTGAAGCAGCTCTAAACTATAAAACACGCATTGCAGAATTGGAAAAGAAAATCGAAAACCACACAGAAGATA
TGAAAGTGACTGCAAGTGTCAACGATGTGGCTGAATCTGTGGAACGAATGACAGGTATCCCAGTATCGCAAATGGGAGCT
TCAGATATCGAACGTTTGAAAGATATGGCCCATCGCTTGCAAGACAAGGTGATTGGTCAAGATAAGGCCGTAGAAGCTGT
AGCTCGTGCTATCCGTCGTAACCGTGCTGGTTTTGATGAAGGAAATCGCCCAATCGGCAGCTTCCTCTTTGTAGGGTCTA
CTGGGGTTGGTAAGACGGAGCTTGCTAAGCAATTGGCACTCGATATGTTTGGAACCCAGGATGCGATTATCCGTTTGGAT
ATGTCTGAATACAGTGACCGCACAGCTGTTTCTAAGCTAATTGGTACAACAGCAGGCTATGTGGGTTATGATGACAATAG
CAATACCTTAACAGAACGTGTTCGTCGCAATCCATACTCTATCATTCTCTTGGATGAAATTGAAAAGGCTGATCCTCAAG
TTATTACCCTTCTCCTCCAAGTTCTAGATGATGGTCGTTTGACAGATGGTCAAGGAAATACAGTAAACTTCAAGAACACT
GTCATTATTGCGACCTCAAATGCTGGATTTGGCTATGAAGCCAACTTGACAGAAGATGCGGATAAACCAGAATTGATGGA
CCGTTTGAAACCCTTCTTCCGTCCAGAATTCCTCAACCGCTTTAATGCAGTCATCGAGTTCTCACAATTGACTAAGGAAG
ACCTTTCTAAGATTGTAGATTTGATGTTGGCTGAAGTTAACCAAACCTTGGCTAAGAAAGACATTGACTTGGTAGTCAGT
CAAGCGGCTAAAGATTATATCACAGAAGAAGGTTACGACGAAGTCATGGGGGTTCGTCCTCTCCGTCGCGTGGTTGAACA
AGAAATTCGTGATAAGGTGACAGACTTCCACTTGGATCATTTAGATGCTAAACATCTGGAAGCAGATATGAAAGATGGCG
TTTTGGTTATTCGTGAGAAAGCCTAA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (443-603)

• ATPase family associated with various cellular activities (AAA) (AAA) (118-250)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (610-680)

• AAA lid domain (AAA_lid_9) (259-354)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	50.078	91.441	0.458
clpE	Streptococcus mutans UA159	49.221	91.583	0.451
clpE	Streptococcus pneumoniae TIGR4	47.95	90.442	0.434
clpE	Streptococcus pneumoniae Rx1	47.95	90.442	0.434
clpE	Streptococcus pneumoniae D39	47.95	90.442	0.434
clpE	Streptococcus pneumoniae R6	47.95	90.442	0.434
clpC	Bacillus subtilis subsp. subtilis str. 168	44.684	92.582	0.414
clpC	Streptococcus pneumoniae Rx1	42.654	90.3	0.385
clpC	Streptococcus pneumoniae D39	42.654	90.3	0.385
clpC	Streptococcus pneumoniae TIGR4	42.496	90.3	0.384
clpC	Streptococcus thermophilus LMD-9	42.496	90.3	0.384
clpC	Streptococcus thermophilus LMG 18311	42.338	90.3	0.382
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.112	88.017	0.379
clpC	Streptococcus mutans UA159	41.909	88.16	0.369