Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   OPT59_RS08605 Genome accession   NZ_CP125360
Coordinates   1718082..1719407 (-) Length   441 a.a.
NCBI ID   WP_015017291.1    Uniprot ID   A0A9X8T4I6
Organism   Streptococcus dysgalactiae subsp. equisimilis strain UT_120444     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1713082..1724407
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OPT59_RS08590 (OPT59_08590) - 1715665..1716687 (-) 1023 Protein_1631 IS30 family transposase -
  OPT59_RS08595 (OPT59_08595) raiA 1716817..1717365 (-) 549 WP_014612499.1 ribosome-associated translation inhibitor RaiA -
  OPT59_RS11295 - 1717445..1718110 (-) 666 WP_012767419.1 ComF family protein -
  OPT59_RS08605 (OPT59_08605) comFA/cflA 1718082..1719407 (-) 1326 WP_015017291.1 DEAD/DEAH box helicase Machinery gene
  OPT59_RS08610 (OPT59_08610) - 1719463..1720101 (+) 639 WP_015017292.1 YigZ family protein -
  OPT59_RS08615 (OPT59_08615) cysK 1720205..1721140 (+) 936 WP_003062335.1 cysteine synthase A -
  OPT59_RS08620 (OPT59_08620) - 1721292..1721651 (-) 360 WP_015017293.1 S1 RNA-binding domain-containing protein -
  OPT59_RS08625 (OPT59_08625) - 1721651..1723051 (-) 1401 WP_042357970.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  OPT59_RS08630 (OPT59_08630) - 1723088..1723729 (-) 642 WP_014612503.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 49283.45 Da        Isoelectric Point: 9.7069

>NTDB_id=831287 OPT59_RS08605 WP_015017291.1 1718082..1719407(-) (comFA/cflA) [Streptococcus dysgalactiae subsp. equisimilis strain UT_120444]
MEGIENSYGRLFLKHQLPKEVNHLAKTLESIVAIKGKVTCQRCHYQITAEARLPSGTYYCRFCLVFGRNQADRPLYYIPP
HPFPIANYLQWKGILTPYQESISNQLVKNVHAKKPTLVHAVTGAGKTEMIYGAIAAVVNAGGWVCLASPRVDVCIELANR
LKAAFSCRVTLLHADSEAYQRSPIIVATTHQLLTFYKAFDLLIIDEVDAFPFVNNHQLQYAAQQAAKEGASSIVLTATST
KELEEQVKSGELEKLTLARRFHDNPLILPKFIRSFGLLKKIHCQKLPRALVKSISQQRKTGCPLLIFLPIIAMAELVTEL
LKLAFPEEQIACVSSQSADRVKDIDAFRQGKKGILVTTTILERGVTFPGVDVFVLMAQHRGYSSQSLVQIAGRVGRSIER
PTGKVYFFHDGISQAMRNARKEIKEMNQKGYLNDMPPMSTI

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=831287 OPT59_RS08605 WP_015017291.1 1718082..1719407(-) (comFA/cflA) [Streptococcus dysgalactiae subsp. equisimilis strain UT_120444]
ATGGAAGGTATCGAAAACAGTTACGGTCGTTTATTTTTAAAACATCAATTGCCAAAAGAAGTAAATCATCTGGCAAAGAC
CTTGGAAAGTATAGTAGCCATAAAAGGTAAAGTCACTTGTCAACGCTGTCATTATCAGATAACCGCAGAAGCGAGATTAC
CAAGTGGCACTTACTACTGCCGCTTCTGTCTCGTTTTTGGCCGAAATCAAGCTGATAGGCCTCTTTATTATATACCTCCA
CATCCTTTTCCTATAGCCAATTATCTTCAATGGAAGGGGATATTAACGCCCTACCAAGAAAGTATTTCAAACCAATTAGT
CAAGAATGTTCATGCTAAAAAACCTACTTTAGTGCATGCTGTTACCGGAGCCGGCAAGACAGAGATGATTTATGGAGCCA
TAGCAGCAGTTGTTAATGCTGGAGGTTGGGTTTGTTTAGCCAGCCCAAGGGTCGATGTTTGTATAGAACTTGCTAATCGC
TTAAAAGCTGCTTTTTCTTGCCGGGTTACTCTTTTACATGCTGACTCAGAAGCTTATCAAAGAAGTCCTATTATAGTAGC
TACTACCCATCAATTACTGACCTTTTATAAGGCTTTTGATCTTTTAATCATTGATGAAGTTGATGCTTTTCCTTTTGTCA
ATAATCATCAACTACAATATGCAGCGCAGCAAGCCGCTAAAGAAGGCGCTAGTAGTATCGTATTGACCGCGACATCGACC
AAAGAACTGGAAGAGCAGGTCAAAAGTGGGGAACTAGAGAAGTTGACATTAGCTAGACGATTCCACGATAATCCTTTGAT
TCTTCCGAAATTTATCAGGAGTTTTGGTCTATTAAAAAAAATTCACTGTCAAAAACTTCCTCGAGCTCTTGTTAAATCTA
TCAGTCAACAAAGGAAAACAGGATGTCCACTGCTAATTTTCCTTCCTATTATTGCCATGGCAGAATTAGTTACTGAATTA
TTAAAGTTAGCTTTTCCAGAGGAACAAATTGCCTGTGTCTCTAGCCAATCAGCTGACAGAGTTAAAGACATTGATGCCTT
TCGTCAAGGAAAGAAAGGTATTTTGGTGACCACCACAATATTGGAAAGGGGTGTTACTTTCCCAGGCGTGGATGTCTTTG
TGCTTATGGCACAGCATCGAGGATACAGTTCTCAAAGCTTGGTTCAAATCGCAGGTCGTGTGGGGAGATCTATCGAAAGG
CCAACAGGGAAGGTGTATTTCTTTCACGATGGGATTAGCCAAGCAATGCGCAATGCAAGAAAAGAAATTAAAGAAATGAA
TCAGAAAGGTTATTTGAATGATATGCCTCCTATGTCAACAATTTAG

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(289-396)

DEAD/DEAH box helicase (DEAD)

(99-244)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

53.302

96.145

0.512
  comFA/cflA Streptococcus pneumoniae D39

53.302

96.145

0.512
  comFA/cflA Streptococcus pneumoniae R6

53.302

96.145

0.512
  comFA/cflA Streptococcus pneumoniae TIGR4

53.302

96.145

0.512
  comFA/cflA Streptococcus mitis NCTC 12261

51.852

97.959

0.508
  comFA/cflA Streptococcus mitis SK321

52.214

97.279

0.508
  comFA Lactococcus lactis subsp. cremoris KW2

46.465

89.796

0.417
  comFA Latilactobacillus sakei subsp. sakei 23K

37.587

97.732

0.367