Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   OPT59_RS07955 Genome accession   NZ_CP125360
Coordinates   1575616..1577907 (+) Length   763 a.a.
NCBI ID   WP_003060519.1    Uniprot ID   A0AB38Y0Z5
Organism   Streptococcus dysgalactiae subsp. equisimilis strain UT_120444     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1570616..1582907
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OPT59_RS07930 (OPT59_07930) feoB 1570706..1572865 (-) 2160 WP_015017220.1 ferrous iron transport protein B -
  OPT59_RS07935 (OPT59_07935) - 1572862..1573341 (-) 480 WP_003056958.1 ferrous iron transport protein A -
  OPT59_RS07940 (OPT59_07940) - 1573540..1574274 (-) 735 WP_015017221.1 amino acid ABC transporter ATP-binding protein -
  OPT59_RS07945 (OPT59_07945) - 1574274..1574960 (-) 687 WP_165737040.1 amino acid ABC transporter permease -
  OPT59_RS07950 (OPT59_07950) - 1575088..1575318 (-) 231 WP_003051836.1 DUF1797 family protein -
  OPT59_RS07955 (OPT59_07955) clpE 1575616..1577907 (+) 2292 WP_003060519.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  OPT59_RS07960 (OPT59_07960) - 1578025..1578480 (+) 456 WP_022554961.1 NUDIX hydrolase -
  OPT59_RS07965 (OPT59_07965) - 1578530..1578832 (+) 303 WP_003051842.1 DUF1827 family protein -
  OPT59_RS07970 (OPT59_07970) ileS 1579235..1582036 (-) 2802 WP_003062434.1 isoleucine--tRNA ligase -

Sequence

Protein


Download         Length: 763 a.a.        Molecular weight: 84971.26 Da        Isoelectric Point: 5.3453

>NTDB_id=831285 OPT59_RS07955 WP_003060519.1 1575616..1577907(+) (clpE) [Streptococcus dysgalactiae subsp. equisimilis strain UT_120444]
MLCQNCNLNESTIHLYTNVNGKQKQVDLCQNCYQIMKTDPTNPILGGLNGGQRAQERSSNPFFDDFFGDLNNFRAFGNLP
NTPPTQAGQNGNGGGRHGGHFNGQRPTQPQTPNQQAKGLLEEFGINVTDIARHGDIDPVIGRDDEITRVIEILNRRTKNN
PVLIGEPGVGKTAVVEGLAQKIVDGTVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRKDVILFIDEIHE
IVGAGSAGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHH
VKYSPAAIEAAAHLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDKRLIEAENLKAQATRDEDYERAAYFRDQ
IAKYKEMQAQKVDEQDIPIITEKTIEAIIEQKTNIPVGDLKEKEQSQLVNLANDLKAHVIGQDDAVDKIAKAIRRNRVGL
GTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPY
SLILLDEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKSEASVGFGAAREGRTSSVLGELSNFFS
PEFMNRFDGIIEFKALSKDNLLHIVDLMLEDVNKRLSYNGIHLDVTQKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAIT
DYYLEHPTEKDLRAIMTSNSNIMIKAAKKDETVTAKQDKTDEN

Nucleotide


Download         Length: 2292 bp        

>NTDB_id=831285 OPT59_RS07955 WP_003060519.1 1575616..1577907(+) (clpE) [Streptococcus dysgalactiae subsp. equisimilis strain UT_120444]
ATGCTTTGTCAAAATTGTAATTTAAACGAATCAACCATTCACCTCTACACGAATGTTAATGGAAAACAAAAACAAGTTGA
CCTTTGTCAAAACTGTTATCAAATCATGAAGACTGACCCTACTAATCCTATTTTAGGTGGCCTAAATGGAGGTCAAAGAG
CCCAAGAACGCTCATCCAACCCCTTCTTTGATGACTTTTTTGGGGACTTAAATAATTTTAGAGCCTTTGGCAACCTTCCA
AATACCCCACCTACTCAGGCAGGGCAAAATGGAAATGGTGGGGGACGCCATGGTGGTCATTTCAATGGACAACGTCCCAC
TCAACCACAAACACCAAATCAGCAAGCAAAAGGCTTGCTAGAAGAATTTGGCATTAATGTGACCGATATTGCAAGACATG
GTGATATTGACCCTGTCATCGGTCGAGATGACGAGATTACACGTGTCATCGAAATCCTTAACCGTCGGACTAAAAATAAC
CCTGTGCTTATTGGGGAACCAGGAGTTGGTAAAACAGCTGTTGTAGAAGGTCTAGCCCAAAAAATTGTAGATGGCACAGT
ACCTCACAAATTGCAAGGTAAGCAAGTGATCCGTCTAGATGTGGTTAGTCTTGTTCAAGGCACAGGTATCCGTGGTCAAT
TCGAAGAACGCATGCAAAAATTAATGGAAGAAATTCGTCAACGCAAAGATGTGATTCTCTTTATTGATGAAATTCATGAA
ATTGTAGGTGCTGGTTCTGCTGGAGATGGCAATATGGATGCTGGCAATATTTTAAAACCAGCCTTGGCCCGTGGTGAGTT
GCAACTCGTTGGTGCTACTACCTTAAATGAATACCGTATTATTGAAAAAGATGCTGCCTTGGAGCGGCGGATGCAGCCGG
TGAAAGTTGACGAACCTTCTGTAGAAGAAACCATTACCATCTTAAAAGGTATCCAACCCAAATATGAAGACTATCATCAT
GTCAAATATAGCCCAGCAGCTATCGAGGCTGCTGCACACTTATCCAATCGCTACATCCAAGACCGATTCCTCCCTGATAA
GGCCATTGACCTTCTGGACGAAGCTGGTTCAAAAATGAATTTAACTCTTAATTTTGTTGACCCTAAAGAGATTGACAAAC
GTCTGATTGAAGCAGAAAACCTCAAAGCTCAAGCAACTCGTGACGAAGATTACGAACGAGCAGCCTATTTCCGTGATCAA
ATTGCGAAATACAAGGAAATGCAAGCTCAAAAAGTCGACGAACAGGATATTCCTATCATTACTGAAAAAACCATTGAAGC
CATCATTGAACAAAAAACCAATATTCCAGTTGGCGACTTGAAAGAAAAAGAACAATCTCAACTCGTTAATTTGGCTAATG
ATTTGAAAGCTCACGTGATTGGCCAAGATGATGCCGTTGACAAAATTGCCAAGGCCATTCGCCGGAACCGTGTGGGATTG
GGAACTCCAAATCGTCCTATTGGTTCTTTCCTATTCGTTGGGCCAACAGGTGTTGGTAAAACAGAGTTGTCTAAGCAACT
AGCTATTGAACTCTTTGGCTCTGCTGACAATATGATTCGCTTTGATATGTCCGAATACATGGAAAAACATGCCGTTGCTA
AATTAGTCGGGGCTCCTCCTGGTTATGTGGGCTATGAAGAAGCTGGCCAGTTAACGGAACAAGTTCGCCGCAACCCATAT
TCACTTATTCTCTTAGATGAGGTGGAAAAGGCTCATCCTGACGTCATGCACATGTTTTTACAAGTTCTTGATGATGGCCG
TTTAACAGATGGTCAAGGACGGACAGTCAGCTTCAAGGATACTATTATTATCATGACCTCTAATGCCGGAACAGGTAAAA
GCGAAGCTTCTGTTGGATTTGGTGCAGCTAGAGAAGGACGAACAAGCTCTGTCCTTGGTGAATTAAGTAACTTCTTCAGC
CCAGAGTTCATGAACCGTTTCGATGGTATTATTGAATTTAAGGCCTTGAGCAAAGATAACCTCTTGCATATCGTTGATTT
AATGCTGGAAGATGTTAATAAGCGCTTAAGCTATAATGGGATTCACCTTGATGTGACACAAAAAGTCAAAGAAAAATTAG
TAGATTTAGGCTATGATCCTAAAATGGGTGCTCGACCACTCCGTCGTACCATCCAAGATTATATCGAAGATGCGATTACG
GACTACTATTTGGAACACCCCACTGAAAAGGACTTGCGTGCCATAATGACAAGTAACAGTAATATCATGATTAAAGCTGC
CAAAAAAGATGAAACGGTAACAGCTAAACAAGATAAGACCGACGAGAACTAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(485-648)

ATPase family associated with various cellular activities (AAA) (AAA)

(162-281)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(656-730)

AAA lid domain (AAA_lid_9)

(300-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

85.582

99.083

0.848
  clpE Streptococcus pneumoniae Rx1

84.19

99.476

0.837
  clpE Streptococcus pneumoniae D39

84.19

99.476

0.837
  clpE Streptococcus pneumoniae R6

84.19

99.476

0.837
  clpE Streptococcus pneumoniae TIGR4

84.058

99.476

0.836
  clpC Lactococcus lactis subsp. cremoris KW2

76.495

96.461

0.738
  clpC Bacillus subtilis subsp. subtilis str. 168

51.138

86.37

0.442
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.462

85.19

0.396
  clpC Streptococcus pneumoniae TIGR4

48

81.913

0.393
  clpC Streptococcus pneumoniae Rx1

48

81.913

0.393
  clpC Streptococcus pneumoniae D39

48

81.913

0.393
  clpC Streptococcus mutans UA159

47.573

80.996

0.385
  clpC Streptococcus thermophilus LMD-9

46.635

81.782

0.381
  clpC Streptococcus thermophilus LMG 18311

46.314

81.782

0.379