Detailed information NTG0831270

Bioinformatically predicted

Overview

• Name: vicK
• Type: Regulator
• Locus tag: OPT59_RS03280
• Genome accession: NZ_CP125360
• Coordinates: 620977..622329 (+)
• Length: 450 a.a.
• NCBI ID: WP_014612101.1
• Uniprot ID: A0AB38Y2E7
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain UT_120444
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 615977..627329

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OPT59_RS03255 (OPT59_03255)	-	617044..617691 (-)	648	WP_003057245.1	amino acid ABC transporter permease	-
OPT59_RS03260 (OPT59_03260)	-	617706..618407 (-)	702	WP_015016780.1	amino acid ABC transporter permease	-
OPT59_RS03265 (OPT59_03265)	-	618421..619221 (-)	801	WP_003057243.1	transporter substrate-binding domain-containing protein	-
OPT59_RS03270 (OPT59_03270)	-	619221..620015 (-)	795	WP_003057217.1	amino acid ABC transporter ATP-binding protein	-
OPT59_RS03275 (OPT59_03275)	vicR	620274..620984 (+)	711	WP_003057225.1	response regulator YycF	Regulator
OPT59_RS03280 (OPT59_03280)	vicK	620977..622329 (+)	1353	WP_014612101.1	cell wall metabolism sensor histidine kinase VicK	Regulator
OPT59_RS03285 (OPT59_03285)	vicX	622333..623142 (+)	810	WP_003059746.1	MBL fold metallo-hydrolase	Regulator
OPT59_RS03290 (OPT59_03290)	rnc	623900..624592 (+)	693	WP_003057240.1	ribonuclease III	-

Sequence

Protein

• Length: 450 a.a.
• Molecular weight: 51476.06 Da
• Isoelectric Point: 5.7411

>NTDB_id=831270 OPT59_RS03280 WP_014612101.1 620977..622329(+) (vicK) [Streptococcus dysgalactiae subsp. equisimilis strain UT_120444]
MTRDIIGNLSAFELAILLLLVFVAFYFIHLAVRDYRNARIIRMMSHKIRDLINGRYTDMINEKADIELMELADQLNDLSD
VFRLTHENLAQEKNRLASILAYMSDGVLATDRSGKIIMINETARKQLNLTKEKALEKNITDLLEGDTPYTYRELVSKTPV
VTVNSRNDMGEFVTLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGAIK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVTQLSVEMTNFTAFMTSILNRFDLVKNQHTGTGKVYEIVRDYPITS
VWLEIDNDKMTQVIENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEDDID

Nucleotide

• Length: 1353 bp

>NTDB_id=831270 OPT59_RS03280 WP_014612101.1 620977..622329(+) (vicK) [Streptococcus dysgalactiae subsp. equisimilis strain UT_120444]
ATGACTAGAGATATCATTGGAAACTTATCCGCTTTTGAATTAGCGATTCTCTTATTACTTGTTTTTGTTGCCTTTTATTT
TATTCACTTAGCGGTGCGTGATTACCGAAATGCCCGTATTATTCGAATGATGAGCCATAAAATCAGAGACCTGATTAATG
GCCGTTATACCGACATGATTAACGAAAAGGCTGACATTGAATTGATGGAACTGGCAGATCAGTTAAACGATCTCTCAGAC
GTGTTTCGCTTAACCCATGAGAATCTTGCCCAGGAAAAAAATCGCTTGGCCAGCATTCTGGCCTATATGTCAGATGGCGT
ACTTGCCACAGACCGGTCTGGTAAAATCATCATGATTAACGAGACAGCTCGCAAGCAGCTCAATCTGACCAAGGAGAAGG
CCCTTGAAAAGAACATTACCGATTTGTTGGAGGGAGATACCCCCTATACCTATCGTGAATTGGTTTCCAAAACGCCTGTT
GTGACGGTCAATAGTCGCAATGACATGGGTGAGTTTGTTACATTACGTTTACGCTTCGCCTTAAACAGACGAGAAAGTGG
TTTTATTTCTGGTTTGGTTGTGGTGCTCCATGACACTACAGAACAGGAAAAGGAAGAACGTGAACGCCGGTTGTTTGTTT
CTAATGTGAGTCATGAGTTGAGAACACCTTTGACATCGGTGAAATCCTACTTGGAGGCTCTTGACGAAGGTGCCATCAAG
GAAGATATTGCTCCAAGTTTCATAAAAGTTTCTCTTGATGAAACCAATCGGATGATGCGTATGATTTCCGATCTTTTAAA
CTTGTCTCGCATTGATAACCAAGTAACTCAGTTATCTGTCGAGATGACCAATTTTACAGCTTTTATGACATCTATCCTGA
ACCGATTTGACCTAGTTAAAAACCAGCACACCGGTACTGGCAAGGTTTATGAAATTGTGAGAGACTATCCGATTACCTCT
GTTTGGCTGGAAATTGATAATGATAAGATGACGCAGGTTATTGAAAATATCCTAAACAACGCGATTAAATACTCTCCTGA
TGGTGGGAAAATCACTGTTCGCATGAAAACAACCGACACGCAATTGATTATTTCCATCTCAGACCAAGGCTTAGGCATTC
CGAAGAAGGATCTGCCCCTTATTTTTGACCGTTTTTACCGTGTGGACAAGGCAAGAAGCCGTGCTCAAGGTGGAACTGGT
CTAGGGCTTGCCATTGCCAAAGAAATTATTAAGCAGCATCACGGGTTTATTTGGGCGAAGAGTGATTATGGCAAAGGATC
AACCTTTACCATCGTCTTGCCATATGAAAAAGATGCTGCCATTTACGAAGAGTGGGAGGATGACATAGATTAA

Domains

Predicted by InterproScan.

• PAS fold (PAS) (95-165)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (326-436)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicK	Streptococcus mutans UA159	73.188	92	0.673
micB	Streptococcus pneumoniae Cp1015	66.588	94.444	0.629