Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   OPT59_RS00735 Genome accession   NZ_CP125360
Coordinates   120608..121639 (+) Length   343 a.a.
NCBI ID   WP_042357807.1    Uniprot ID   A0AB38Y521
Organism   Streptococcus dysgalactiae subsp. equisimilis strain UT_120444     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 115608..126639
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OPT59_RS00725 (OPT59_00725) - 119285..119650 (+) 366 WP_003055257.1 DUF1033 family protein -
  OPT59_RS00730 (OPT59_00730) comGA/cglA 119731..120672 (+) 942 WP_015016543.1 competence type IV pilus ATPase ComGA Machinery gene
  OPT59_RS00735 (OPT59_00735) comYB 120608..121639 (+) 1032 WP_042357807.1 competence type IV pilus assembly protein ComGB Machinery gene
  OPT59_RS00740 (OPT59_00740) comYC 121641..121967 (+) 327 WP_003055259.1 competence type IV pilus major pilin ComGC Machinery gene
  OPT59_RS00745 (OPT59_00745) comGD 121942..122370 (+) 429 WP_041788719.1 competence type IV pilus minor pilin ComGD -
  OPT59_RS00750 (OPT59_00750) comGE 122378..122623 (+) 246 WP_003058569.1 competence type IV pilus minor pilin ComGE -
  OPT59_RS00755 (OPT59_00755) comGF 122604..123044 (+) 441 WP_003061780.1 competence type IV pilus minor pilin ComGF -
  OPT59_RS00760 (OPT59_00760) comGG 123022..123396 (+) 375 WP_012766449.1 competence type IV pilus minor pilin ComGG -
  OPT59_RS00765 (OPT59_00765) comYH 123459..124412 (+) 954 WP_003060701.1 class I SAM-dependent methyltransferase Machinery gene
  OPT59_RS00770 (OPT59_00770) - 124471..125667 (+) 1197 WP_003058485.1 acetate kinase -
  OPT59_RS00775 (OPT59_00775) - 125973..126179 (+) 207 WP_003058508.1 helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 343 a.a.        Molecular weight: 38983.37 Da        Isoelectric Point: 9.2055

>NTDB_id=831251 OPT59_RS00735 WP_042357807.1 120608..121639(+) (comYB) [Streptococcus dysgalactiae subsp. equisimilis strain UT_120444]
MTFLQRDISVRSKQGLKKLSSKEQYKLIQLLANLLLTGFNLAEIIAFLTKSHLIPEPYVLRMEEALLKGRGLADMLAGIG
FSDAILTQISLADGHGNIETTLVNIQGYLNQMAKLKRKTIEVVTYPIILLVFLFVMILGLRHYVMPQLEAQNQLTIFLTH
FPAIFFGIILFIGVLLGGIWLHWRSQSRLKLFTHFSAYPVLGKLLQQYLTAYYAREWGTLIGQGLELPVILDIMTMEKSL
FMQELAEDIRVSLLAGQAFHDKVATYPFFKKELSLMITYGEIKSKLGSELEIYAQESWTQFFSQLHQATQFIQPIIFLVI
ALTIVMIYAAILLPIYQNMGGVL

Nucleotide


Download         Length: 1032 bp        

>NTDB_id=831251 OPT59_RS00735 WP_042357807.1 120608..121639(+) (comYB) [Streptococcus dysgalactiae subsp. equisimilis strain UT_120444]
ATGACCTTCTTGCAGCGGGACATCTCAGTCCGGAGCAAGCAAGGTTTGAAAAAATTATCCAGTAAGGAACAATACAAACT
AATTCAGCTATTAGCTAACCTTTTGTTAACAGGATTTAACTTGGCTGAGATAATAGCTTTCTTAACAAAAAGTCATTTGA
TTCCCGAGCCCTATGTTCTCCGCATGGAAGAAGCACTCTTAAAAGGTCGAGGGCTGGCAGATATGTTAGCTGGGATAGGT
TTTTCGGATGCTATTTTAACTCAAATTAGTTTAGCAGATGGTCACGGAAACATTGAGACGACGCTTGTTAATATTCAGGG
CTATCTCAACCAAATGGCTAAACTTAAACGAAAAACCATTGAAGTCGTCACCTATCCGATTATTCTCCTGGTATTTCTTT
TTGTGATGATATTAGGGTTAAGGCATTATGTTATGCCTCAATTAGAAGCTCAAAATCAGCTTACTATTTTTCTGACTCAT
TTTCCAGCTATTTTCTTTGGTATTATCCTTTTTATAGGTGTGCTGTTAGGGGGAATTTGGCTGCATTGGCGATCGCAAAG
TCGCCTCAAGCTTTTTACTCACTTCAGTGCTTATCCTGTTTTAGGGAAACTCTTACAACAGTATCTGACGGCTTATTATG
CTAGAGAATGGGGAACATTGATTGGACAGGGACTTGAATTACCAGTCATTCTGGATATTATGACCATGGAGAAATCTTTA
TTCATGCAAGAATTGGCTGAAGATATTCGAGTTAGTTTATTGGCAGGACAAGCTTTTCATGATAAGGTAGCTACCTATCC
TTTCTTTAAAAAAGAGTTAAGTTTGATGATTACTTATGGAGAGATTAAATCCAAGTTAGGAAGTGAACTAGAGATTTATG
CTCAAGAGAGTTGGACTCAGTTTTTCAGCCAACTTCATCAAGCAACTCAGTTTATTCAACCGATTATCTTTTTAGTGATT
GCTCTGACGATTGTCATGATTTATGCAGCAATTTTATTACCAATTTATCAAAATATGGGAGGCGTTTTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(28-146)

Type II secretion system (T2SS), protein F (T2SSF)

(214-334)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

53.392

98.834

0.528
  comYB Streptococcus mutans UA159

53.392

98.834

0.528
  comYB Streptococcus gordonii str. Challis substr. CH1

48.673

98.834

0.481
  comGB/cglB Streptococcus mitis NCTC 12261

45.97

97.668

0.449
  comGB/cglB Streptococcus mitis SK321

45.345

97.085

0.44
  comGB/cglB Streptococcus pneumoniae Rx1

43.844

97.085

0.426
  comGB/cglB Streptococcus pneumoniae D39

43.844

97.085

0.426
  comGB/cglB Streptococcus pneumoniae R6

43.844

97.085

0.426
  comGB/cglB Streptococcus pneumoniae TIGR4

43.844

97.085

0.426
  comGB Lactococcus lactis subsp. cremoris KW2

42.773

98.834

0.423