Detailed information NTG0830846

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: QL280_RS08940
• Genome accession: NZ_CP125291
• Coordinates: 1753650..1754687 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727275.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 105_Kz
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1748650..1759687

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QL280_RS08915 (QL280_08915)	-	1749389..1750720 (-)	1332	Protein_1747	hemolysin family protein	-
QL280_RS08920 (QL280_08920)	endA	1751011..1751835 (-)	825	WP_001036779.1	DNA-entry nuclease EndA	Machinery gene
QL280_RS08925 (QL280_08925)	-	1751874..1752062 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
QL280_RS08930 (QL280_08930)	murA	1752055..1753338 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
QL280_RS08935 (QL280_08935)	-	1753362..1753592 (-)	231	WP_000250384.1	DUF1146 family protein	-
QL280_RS08940 (QL280_08940)	sepM	1753650..1754687 (-)	1038	WP_000727275.1	SepM family pheromone-processing serine protease	Regulator
QL280_RS08945 (QL280_08945)	coaD	1754671..1755159 (-)	489	WP_001280742.1	pantetheine-phosphate adenylyltransferase	-
QL280_RS08950 (QL280_08950)	rsmD	1755149..1755688 (-)	540	WP_000706962.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
QL280_RS08955 (QL280_08955)	asnA	1755753..1756745 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
QL280_RS08960 (QL280_08960)	-	1756856..1757539 (-)	684	WP_001016917.1	Bax inhibitor-1/YccA family protein	-
QL280_RS08965 (QL280_08965)	-	1757595..1758335 (-)	741	WP_000152681.1	RNA methyltransferase	-
QL280_RS08970 (QL280_08970)	-	1758369..1758647 (+)	279	WP_001174613.1	acylphosphatase	-
QL280_RS08975 (QL280_08975)	yidC	1758725..1759651 (+)	927	WP_000835941.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37609.64 Da
• Isoelectric Point: 4.9590

>NTDB_id=830846 QL280_RS08940 WP_000727275.1 1753650..1754687(-) (sepM) [Streptococcus pneumoniae strain 105_Kz]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKEILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=830846 QL280_RS08940 WP_000727275.1 1753650..1754687(-) (sepM) [Streptococcus pneumoniae strain 105_Kz]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGAGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAAATCATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588