Detailed information NTG0830530

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: QLH34_RS18615
• Genome accession: NZ_CP125279
• Coordinates: 3663029..3664192 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain FLU-1
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3658029..3669192

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QLH34_RS18585 (QLH34_18585)	-	3658293..3658712 (-)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-
QLH34_RS18590 (QLH34_18590)	comFC	3658786..3659475 (-)	690	WP_199022660.1	phosphoribosyltransferase family protein	Machinery gene
QLH34_RS18595 (QLH34_18595)	-	3659481..3659765 (-)	285	WP_007407481.1	competence protein ComFB	-
QLH34_RS18600 (QLH34_18600)	comFA	3659823..3661208 (-)	1386	WP_124692700.1	DEAD/DEAH box helicase	Machinery gene
QLH34_RS18605 (QLH34_18605)	-	3661317..3662165 (-)	849	WP_003151387.1	DegV family protein	-
QLH34_RS18610 (QLH34_18610)	degU	3662263..3662952 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
QLH34_RS18615 (QLH34_18615)	degS	3663029..3664192 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
QLH34_RS18620 (QLH34_18620)	-	3664415..3665062 (+)	648	WP_007614107.1	YigZ family protein	-
QLH34_RS18625 (QLH34_18625)	-	3665067..3666287 (+)	1221	WP_007407486.1	LCP family protein	-
QLH34_RS18630 (QLH34_18630)	-	3666386..3667462 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
QLH34_RS18635 (QLH34_18635)	-	3667595..3668791 (-)	1197	WP_218791395.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=830530 QLH34_RS18615 WP_007407484.1 3663029..3664192(-) (degS) [Bacillus velezensis strain FLU-1]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=830530 QLH34_RS18615 WP_007407484.1 3663029..3664192(-) (degS) [Bacillus velezensis strain FLU-1]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951