Detailed information NTG0830318

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: SPM78_RS08950
• Genome accession: NZ_CP139424
• Coordinates: 1903146..1905695 (-)
• Length: 849 a.a.
• NCBI ID: WP_003139311.1
• Uniprot ID: A0A0H2ZBC1
• Organism: Pseudomonas aeruginosa strain 136790
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1898146..1910695

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPM78_RS08925 (SPM78_08925)	-	1898425..1898820 (+)	396	WP_003089513.1	DUF4280 domain-containing protein	-
SPM78_RS08930 (SPM78_08930)	-	1898843..1899379 (-)	537	WP_023095583.1	toxin-antitoxin system YwqK family antitoxin	-
SPM78_RS08935 (SPM78_08935)	tssI	1899390..1901396 (-)	2007	WP_023095584.1	type VI secretion system tip protein VgrG	-
SPM78_RS08940 (SPM78_08940)	-	1901433..1902500 (-)	1068	WP_023095585.1	M91 family zinc metallopeptidase	-
SPM78_RS08945 (SPM78_08945)	-	1902539..1903072 (-)	534	WP_003089506.1	hypothetical protein	-
SPM78_RS08950 (SPM78_08950)	clpC	1903146..1905695 (-)	2550	WP_003139311.1	type VI secretion system ATPase TssH	Regulator
SPM78_RS08955 (SPM78_08955)	tssG	1905697..1906713 (-)	1017	WP_003114517.1	type VI secretion system baseplate subunit TssG	-
SPM78_RS08960 (SPM78_08960)	tssF	1906677..1908470 (-)	1794	WP_019486282.1	type VI secretion system baseplate subunit TssF	-
SPM78_RS08965 (SPM78_08965)	tssE	1908454..1908879 (-)	426	WP_003089496.1	type VI secretion system baseplate subunit TssE	-
SPM78_RS08970 (SPM78_08970)	-	1908892..1909389 (-)	498	WP_003089495.1	Hcp family type VI secretion system effector	-

Sequence

Protein

• Length: 849 a.a.
• Molecular weight: 92457.70 Da
• Isoelectric Point: 5.1045

>NTDB_id=830318 SPM78_RS08950 WP_003139311.1 1903146..1905695(-) (clpC) [Pseudomonas aeruginosa strain 136790]
MELAALIGRLNPDCRRALERAAQRCLQRTHHYVEIEHLLLELLDIDGGDFACLLPRFGLERDALVAEINLSLELFKAGNT
RTPALSAHTIGLLEDAVVHASVLGQAQIRSGLLLLALLDREERRALLLNSASSLLRIPHEALQANLLEWIQTSREQPPAP
NRPAAGGDKPESAPDPLLDQYTQDLTAEARAGRIDPIVGRDGEIRQCVDILLRRRQNNPILVGAPGVGKTAVVEGLALRI
AAGEVPPSLQEVILRVLDLGLLQAGASMKGEFEQRLKGVIDAVRNSAQPIILFIDEAHTLIGAGGAEGGSDAANLLKPAL
ARGELRTLAATTWLEYKKYFEKDPALTRRFQLVQVEEPDEATAVEMLRGVAGKLEQHHGVQIMDAAIVDAVKLSHRYISG
RQLPDKAISVLDTACARVALGQHDVPPPLESLRHREQALEEELQRLRREQATGLDHSARITALESESGDNRRTIRELETR
WDEEREAVRELLDTRRELLALSESADAAKPDEELDGRIDHLAAELARLAAGLEAIRQDDPLVPEQVDSRTVAAVIAGWTG
IPVGKMLADEAHAIRSLAQRMGQRVMGQEAALGAIAQRIQAYRAGLSDPAKPVGVFLLPGPTGVGKTETAYALADALYGG
ERNLISINLSEYQEAHTVSQLKGAPPGYVGYGSGGVLTEAVRRKPYSVVLLDEIEKAHPDVLEAFYNVFDKGVMEDGTGL
VVDFRNTVILATSNVGAELLLDSPAEQVATPAFDERLRKVLLQTFRPAFLARMTVVPYRPLEEATLEGIVVAKLEKLRER
YKAATGKQFDFDPAIVKAVLAKCSAAGARDIENVLMAQVTGKLAEWVLE

Nucleotide

• Length: 2550 bp

>NTDB_id=830318 SPM78_RS08950 WP_003139311.1 1903146..1905695(-) (clpC) [Pseudomonas aeruginosa strain 136790]
ATGGAACTCGCCGCCCTGATCGGCCGCCTCAACCCGGACTGTCGCCGCGCCCTGGAGCGCGCCGCGCAACGCTGCCTGCA
ACGCACCCATCATTACGTAGAGATCGAGCACCTGCTGCTGGAGCTGCTGGACATCGACGGCGGCGACTTCGCCTGCCTGC
TGCCGCGCTTCGGCCTGGAGCGCGACGCCCTGGTCGCCGAGATCAACCTGTCGCTGGAGCTGTTCAAGGCCGGCAATACC
CGCACTCCGGCGCTGTCCGCGCACACCATCGGCCTGCTCGAGGACGCCGTGGTCCACGCCAGCGTGCTCGGCCAGGCGCA
GATCCGTTCCGGCCTGCTGCTGCTCGCCCTGCTCGACCGCGAGGAGCGCCGCGCCCTGCTGCTGAACAGCGCGTCGTCGC
TACTGCGGATTCCCCACGAGGCCTTGCAGGCCAACCTGCTGGAGTGGATCCAGACCTCCCGCGAACAGCCGCCCGCGCCG
AACCGCCCGGCTGCAGGCGGCGACAAGCCGGAAAGCGCCCCGGACCCGCTGCTCGACCAGTACACCCAGGACCTCACCGC
CGAGGCCCGCGCCGGGCGCATCGACCCCATAGTCGGGCGCGACGGGGAGATCCGCCAGTGCGTCGACATCCTCCTGCGCC
GGCGGCAGAACAACCCGATCCTGGTCGGCGCGCCGGGCGTCGGCAAGACCGCGGTGGTCGAGGGCCTGGCCCTACGCATC
GCCGCCGGCGAGGTGCCGCCGTCGTTGCAGGAGGTGATCCTGCGGGTGCTCGACCTCGGCCTGTTGCAGGCCGGCGCCAG
CATGAAGGGCGAGTTCGAGCAGCGCCTCAAGGGCGTGATCGACGCCGTGCGCAACAGCGCGCAGCCGATCATCCTGTTCA
TCGACGAGGCGCACACGCTGATCGGCGCCGGCGGCGCGGAAGGCGGCAGCGACGCCGCCAACCTGCTCAAGCCGGCCCTG
GCGCGCGGCGAGTTGCGCACCCTGGCGGCCACCACCTGGCTGGAATACAAGAAATACTTCGAGAAGGACCCGGCGCTGAC
CCGGCGCTTCCAGTTGGTCCAGGTCGAGGAGCCGGACGAGGCCACCGCCGTGGAGATGCTGCGCGGCGTCGCCGGCAAGC
TGGAACAGCATCACGGCGTGCAGATCATGGACGCGGCCATCGTCGATGCGGTGAAGCTGTCGCACCGCTACATCTCCGGC
CGCCAGTTACCGGACAAGGCGATCAGCGTGCTCGACACCGCCTGCGCGCGGGTCGCCCTCGGCCAGCACGACGTGCCGCC
GCCGCTGGAAAGCCTGCGCCACCGCGAGCAGGCGCTGGAAGAGGAATTGCAGCGGCTGCGCCGGGAACAGGCCACCGGCC
TCGACCACAGCGCGCGTATCACCGCCCTGGAAAGCGAGTCGGGCGATAACCGCCGGACCATCCGCGAGCTGGAGACCCGC
TGGGACGAGGAACGCGAAGCGGTGCGCGAACTGCTCGACACCCGCCGCGAATTGCTGGCCCTCAGCGAAAGCGCCGACGC
GGCCAAGCCCGACGAGGAACTGGACGGTCGCATCGACCACCTGGCCGCCGAACTGGCGCGCCTGGCGGCCGGCCTCGAAG
CCATCCGCCAGGACGACCCGCTGGTTCCCGAGCAGGTGGACTCGCGTACCGTGGCCGCGGTGATCGCCGGCTGGACCGGC
ATCCCGGTGGGCAAGATGCTCGCCGACGAAGCCCACGCCATCCGTTCCCTGGCGCAACGAATGGGCCAGCGGGTGATGGG
CCAGGAGGCCGCCCTGGGCGCCATCGCCCAGCGCATCCAGGCCTATCGCGCCGGACTCAGCGACCCGGCCAAGCCGGTCG
GCGTATTCCTCCTGCCCGGCCCCACCGGCGTGGGCAAGACCGAGACCGCCTACGCCCTGGCCGACGCCCTCTACGGCGGC
GAACGCAACCTGATCAGCATCAACCTCTCCGAGTACCAGGAGGCCCACACCGTCAGCCAGCTCAAGGGCGCCCCGCCCGG
CTACGTCGGCTACGGCAGCGGCGGCGTGCTCACCGAAGCGGTGCGCCGCAAGCCCTATTCGGTGGTGCTGCTGGACGAGA
TCGAGAAAGCCCATCCGGACGTGCTGGAAGCCTTCTACAACGTGTTCGACAAGGGTGTGATGGAAGACGGCACCGGCCTG
GTGGTGGACTTCAGGAACACCGTGATCCTCGCCACCAGCAACGTCGGCGCCGAACTGCTGCTGGACAGCCCGGCCGAACA
GGTCGCCACCCCGGCCTTCGACGAGCGCCTGCGCAAAGTCTTGCTGCAAACCTTCCGCCCGGCGTTCCTCGCGCGCATGA
CCGTGGTGCCTTACCGGCCGCTGGAGGAAGCCACCCTGGAAGGCATCGTCGTGGCCAAGCTGGAAAAACTGCGGGAACGC
TACAAGGCCGCTACCGGCAAACAGTTCGACTTCGACCCGGCCATCGTCAAGGCCGTGCTCGCCAAGTGCAGCGCGGCGGG
CGCGCGGGATATCGAGAACGTGCTGATGGCGCAGGTGACGGGGAAGTTGGCGGAGTGGGTACTCGAATGA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (611-775)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (781-848)

• AAA lid domain (AAA_lid_9) (360-453)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (21-71)

• ATPase family associated with various cellular activities (AAA) (AAA) (220-332)

3D structure

• AlphaFold DB: A0A0H2ZBC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	37.166	100	0.377