Detailed information NTG0083013

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: H7678_RS07770
• Genome accession: NZ_AP023393
• Coordinates: 1570870..1571907 (-)
• Length: 345 a.a.
• NCBI ID: WP_065355406.1
• Uniprot ID: A0AB38XZ54
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain 89
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1565870..1576907

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7678_RS07740 (SDSE89_15130)	-	1566302..1567531 (+)	1230	WP_003054206.1	IS110 family transposase	-
H7678_RS10790 (SDSE89_15140)	-	1567758..1568119 (-)	362	Protein_1484	ATP-binding cassette domain-containing protein	-
H7678_RS10710 (SDSE89_15150)	-	1568134..1568313 (-)	180	WP_003053686.1	ATP-binding cassette domain-containing protein	-
H7678_RS07755 (SDSE89_15160)	rbsD	1568329..1568727 (-)	399	WP_184010280.1	D-ribose pyranase	-
H7678_RS07760 (SDSE89_15170)	rbsK	1568702..1569613 (-)	912	WP_003053680.1	ribokinase	-
H7678_RS07765 (SDSE89_15180)	-	1569606..1570589 (-)	984	WP_184010283.1	LacI family DNA-binding transcriptional regulator	-
H7678_RS07770 (SDSE89_15190)	sepM	1570870..1571907 (-)	1038	WP_065355406.1	SepM family pheromone-processing serine protease	Regulator
H7678_RS07775 (SDSE89_15200)	coaD	1571894..1572385 (-)	492	WP_003051905.1	pantetheine-phosphate adenylyltransferase	-
H7678_RS07780 (SDSE89_15210)	rsmD	1572375..1572914 (-)	540	WP_014612463.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
H7678_RS07785 (SDSE89_15220)	asnA	1573108..1574100 (-)	993	WP_065355407.1	aspartate--ammonia ligase	-
H7678_RS07790 (SDSE89_15230)	arcC	1574426..1575376 (-)	951	WP_014612465.1	carbamate kinase	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37630.20 Da
• Isoelectric Point: 9.4270

>NTDB_id=83013 H7678_RS07770 WP_065355406.1 1570870..1571907(-) (sepM) [Streptococcus dysgalactiae subsp. equisimilis strain 89]
MKTIKKIKWWLINLIALVALLIVLFFPLPYYVEMPGGAYDIRSVVKVNGKEDKDKGSYQFVAVSLSRASLAQLLYAWLTP
FTEISSVEDTTGGYSDADYIRINQFYMETSQNAAVYQALTLADKPVTLDYKGVYVLDISKDSTFKGTLNLADTVTGVNHK
QFTSSTELVDYVSHLKLGDKVTVQFISNSEPKSETGRIIKLKNGKNGIGIALTDHTKVNSAEKIEFSTQGVGGPSAGLMF
TLDIYDQINKEDLRKGRHIAGTGTIGKDGEVGDIGGAGLKVVAAADAGAEIFFVPNNPVDKAVKKANPKAISNYEEAKRA
AKQLKTKMKIVPVTTVQDALAYLRQ

Nucleotide

• Length: 1038 bp

>NTDB_id=83013 H7678_RS07770 WP_065355406.1 1570870..1571907(-) (sepM) [Streptococcus dysgalactiae subsp. equisimilis strain 89]
ATGAAAACAATTAAAAAAATTAAATGGTGGCTGATTAATCTAATTGCCCTCGTGGCTCTGCTTATCGTCCTTTTTTTCCC
TCTTCCTTATTATGTTGAAATGCCTGGCGGAGCCTATGACATTCGATCTGTGGTCAAGGTTAATGGCAAAGAAGATAAAG
ATAAAGGCTCCTATCAGTTTGTGGCAGTCAGTCTCAGTCGAGCCAGTTTAGCTCAGTTGCTCTATGCTTGGCTAACCCCT
TTTACTGAAATCAGTTCAGTTGAGGATACCACAGGCGGTTATAGCGATGCAGACTATATCCGCATTAATCAATTCTACAT
GGAAACCTCACAAAATGCTGCGGTCTATCAGGCATTGACCTTGGCAGACAAACCAGTTACTTTGGACTACAAAGGGGTAT
ATGTGTTAGATATTAGCAAGGATTCAACCTTTAAAGGTACTTTAAACTTAGCAGATACGGTAACGGGAGTGAATCACAAA
CAATTTACGAGTTCAACAGAACTTGTGGACTATGTCTCTCATTTAAAACTTGGTGATAAGGTGACTGTGCAGTTTATTAG
TAACAGCGAACCTAAGTCTGAAACAGGTCGTATCATCAAACTAAAAAATGGTAAAAATGGTATCGGCATTGCTTTAACAG
ACCATACTAAAGTCAATTCAGCAGAGAAAATCGAGTTTAGTACCCAAGGTGTTGGGGGTCCTAGCGCAGGCTTAATGTTT
ACATTAGATATCTACGACCAAATTAATAAAGAAGACCTTCGTAAAGGAAGACATATCGCCGGGACAGGAACCATTGGTAA
AGATGGTGAAGTTGGAGATATTGGCGGTGCGGGTCTTAAGGTCGTTGCTGCTGCAGATGCTGGTGCTGAGATTTTCTTTG
TGCCGAATAATCCTGTGGATAAAGCTGTTAAAAAAGCCAATCCAAAAGCTATTAGCAATTATGAAGAGGCCAAGCGAGCA
GCCAAGCAGTTAAAAACAAAAATGAAAATTGTTCCTGTAACAACTGTTCAGGATGCCCTAGCCTACCTTCGTCAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-192)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-299)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	71.304	100	0.713