Detailed information NTG0083006

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: H7678_RS04415
• Genome accession: NZ_AP023393
• Coordinates: 872123..874222 (-)
• Length: 699 a.a.
• NCBI ID: WP_065355423.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain 89
• Function: degradation of ComX (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	874720..875154	872123..874222	flank	498

Gene organization within MGE regions

Location: 872123..875154

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7678_RS04415 (SDSE89_08330)	clpC	872123..874222 (-)	2100	WP_065355423.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
H7678_RS04420 (SDSE89_08340)	-	874720..875127 (-)	408	Protein_822	IS30 family transposase	-

Sequence

Protein

• Length: 699 a.a.
• Molecular weight: 77338.99 Da
• Isoelectric Point: 4.8590

>NTDB_id=83006 H7678_RS04415 WP_065355423.1 872123..874222(-) (clpC) [Streptococcus dysgalactiae subsp. equisimilis strain 89]
MTNYYDKDTFGNMDDIFNQLMGNMGGYRSENRRYLVNGREMTPEEFQAYRQTGRLSDKGSEQPTSQGHQTKKDGILAKLG
TNLTEEARQGKLDPVIGRNHEIQDTAEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
EAGTQYRGSFEENIQNMIQEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADMLKPALSRGELTLIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHHNVILPDAVLKAAIDYSIQYIPQRSLPDKAIDLVDMTAAHLAA
QHPVTDLKSLEAEMATQKNIQEEAVAKEDFERALTAKTRIEELQKQMDNHSEDQKVTATVNDIAESVERLTGVPVSNMGA
SDLERLKEISNRLKGHVIGQDGAVEAVARAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLALDLFGSKEAIIRLD
MSEYSDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRNPYAIVLLDEIEKADPQVITLLLQVLDDGRLTDGQGNTINFKNT
VIIATSNAGFGHQEDENTDQPAIMDRIAPYFRPEFLNRFNGVIEFNHLQKEDLEEIVDLMLAEVNQTIAKKGISLAISDD
AKAHLIELGYDHAMGVRPLRRVIEQEIRDRITDFYLDHPEVKNLQASLEQGQLVIHDKN

Nucleotide

• Length: 2100 bp

>NTDB_id=83006 H7678_RS04415 WP_065355423.1 872123..874222(-) (clpC) [Streptococcus dysgalactiae subsp. equisimilis strain 89]
ATGACAAATTATTATGACAAAGATACTTTTGGAAACATGGATGATATCTTTAATCAACTAATGGGCAATATGGGTGGCTA
TCGCAGTGAAAATCGACGCTATTTAGTGAACGGACGCGAAATGACACCTGAAGAATTCCAGGCATATCGTCAAACTGGAC
GTCTGAGCGATAAAGGTAGTGAACAACCTACATCCCAAGGCCATCAGACCAAAAAGGATGGGATTTTAGCTAAACTTGGC
ACCAACTTAACGGAAGAAGCAAGACAAGGAAAACTTGATCCTGTTATTGGTCGCAATCACGAAATTCAAGACACTGCGGA
AATTTTAGCTCGCCGAACAAAGAATAATCCTGTTCTAGTCGGAGATGCTGGTGTTGGTAAAACAGCTGTGGTTGAAGGGC
TAGCTCAAGCTATTGTGAATGGTGACGTCCCTGCTGCTATCAAAAATAAAGAAATCATTTCCATTGATATTTCTGGCCTT
GAAGCAGGCACTCAGTACCGTGGCTCCTTTGAAGAAAATATCCAAAACATGATTCAAGAGGTTAAAGAAGCTGGGAATAT
TATTCTTTTCTTTGATGAAATTCATCAAATCCTTGGTGCAGGTTCTACTGGTGGTGACTCTGGGTCTAAAGGATTAGCTG
ATATGCTAAAACCTGCTCTTTCCCGTGGTGAATTGACACTGATTGGCGCCACAACTCAAGATGAATACCGCAATACCATT
TTAAAAAATGCTGCGCTTGCTCGTCGTTTTAATGAGGTTAAGGTAAATGCACCGTCTGCTGAGGACACCTTCCATATTTT
AATGGGAATCCGAAATCTTTACGAACAACACCATAATGTTATCCTTCCGGATGCTGTTCTTAAAGCTGCGATTGACTATT
CTATTCAGTACATTCCTCAACGTAGTTTACCAGATAAAGCGATTGACTTAGTAGATATGACTGCTGCGCATTTAGCTGCT
CAGCATCCTGTGACTGACCTCAAGTCTCTAGAAGCTGAAATGGCCACTCAAAAGAATATCCAAGAAGAGGCTGTGGCTAA
GGAAGATTTTGAGAGAGCTTTAACCGCTAAAACTCGAATTGAAGAATTGCAAAAACAAATGGACAACCATAGCGAAGACC
AAAAGGTTACTGCTACTGTCAATGACATTGCAGAATCCGTAGAGCGCCTGACTGGTGTCCCAGTGTCCAATATGGGAGCT
AGTGATTTGGAAAGACTCAAAGAAATTAGCAACCGCTTAAAAGGACACGTGATTGGCCAAGATGGAGCTGTTGAAGCTGT
GGCTCGTGCTATTCGCCGTAATCGAGCTGGTTTTGATGATGGCAATCGTCCTATCGGTTCCTTCCTCTTTGTTGGACCAA
CAGGTGTTGGTAAGACAGAATTAGCCAAACAGCTAGCACTGGACCTCTTTGGTTCCAAAGAGGCTATTATTCGACTTGAC
ATGTCCGAATACAGTGATCGTACCGCTGTGTCCAAGCTAATAGGGACAACTGCCGGTTATGTCGGTTATGATGATAATAA
CAATACGTTAACGGAACGAGTTCGTCGCAACCCGTATGCGATTGTTCTATTGGATGAGATTGAAAAAGCCGATCCGCAAG
TCATTACCCTTCTTCTCCAAGTACTAGATGATGGCCGATTAACAGATGGTCAGGGAAACACCATCAACTTTAAAAACACT
GTTATCATTGCTACTTCTAATGCTGGATTTGGGCATCAAGAAGATGAAAATACTGATCAACCTGCTATTATGGACCGTAT
TGCGCCTTACTTTAGACCAGAGTTTCTCAATCGTTTCAATGGGGTTATCGAATTCAATCATCTGCAAAAAGAAGACTTAG
AAGAAATTGTTGATTTAATGTTAGCGGAAGTTAATCAAACCATAGCTAAAAAAGGAATCAGCTTAGCTATCTCTGATGAT
GCTAAAGCTCACTTGATTGAATTAGGTTATGACCACGCAATGGGAGTTCGACCATTACGCCGTGTCATCGAGCAAGAAAT
CCGAGACCGCATTACAGACTTTTACCTCGATCACCCAGAGGTCAAAAACTTACAAGCTAGTCTGGAACAAGGACAGTTAG
TCATTCACGACAAAAACTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (608-679)

• AAA domain (Cdc48 subfamily) (AAA_2) (443-600)

• ATPase family associated with various cellular activities (AAA) (AAA) (118-250)

• AAA lid domain (AAA_lid_9) (259-354)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	47.532	100	0.482
clpE	Streptococcus mutans UA159	46.544	100	0.472
clpE	Streptococcus pneumoniae Rx1	48.447	92.132	0.446
clpE	Streptococcus pneumoniae D39	48.447	92.132	0.446
clpE	Streptococcus pneumoniae R6	48.447	92.132	0.446
clpE	Streptococcus pneumoniae TIGR4	48.367	91.989	0.445
clpC	Bacillus subtilis subsp. subtilis str. 168	44.341	92.275	0.409
clpC	Streptococcus pneumoniae D39	40.943	97.139	0.398
clpC	Streptococcus pneumoniae Rx1	40.943	97.139	0.398
clpC	Streptococcus pneumoniae TIGR4	40.795	97.139	0.396
clpC	Streptococcus thermophilus LMG 18311	42.903	88.698	0.381
clpC	Streptococcus mutans UA159	42.742	88.698	0.379
clpC	Streptococcus thermophilus LMD-9	42.718	88.412	0.378
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.326	88.555	0.375