Detailed information NTG0829940

Bioinformatically predicted

Overview

• Name: pepF
• Type: Regulator
• Locus tag: QLH56_RS01980
• Genome accession: NZ_CP125107
• Coordinates: 419262..421064 (-)
• Length: 600 a.a.
• NCBI ID: WP_003100091.1
• Uniprot ID: A0A1J0MY34
• Organism: Streptococcus iniae strain DFSM220524
• Function: degradation of XIP; competence shut-off (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Prophage	402742..425263	419262..421064	within	0
IScluster/Tn	421921..423026	419262..421064	flank	857

Gene organization within MGE regions

Location: 402742..425263

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QLH56_RS01910 (QLH56_01910)	nrdH	402742..402960 (+)	219	WP_003100113.1	glutaredoxin-like protein NrdH	-
QLH56_RS01915 (QLH56_01915)	nrdE	402990..405149 (+)	2160	WP_003100112.1	class 1b ribonucleoside-diphosphate reductase subunit alpha	-
QLH56_RS01920 (QLH56_01920)	nrdF	405613..406572 (+)	960	WP_003100111.1	class 1b ribonucleoside-diphosphate reductase subunit beta	-
QLH56_RS01925 (QLH56_01925)	-	406666..407916 (+)	1251	WP_003100110.1	chloride channel protein	-
QLH56_RS01930 (QLH56_01930)	-	407995..409130 (+)	1136	Protein_381	IS3 family transposase	-
QLH56_RS01935 (QLH56_01935)	-	409201..410376 (-)	1176	WP_003100106.1	pyridoxal phosphate-dependent aminotransferase	-
QLH56_RS01940 (QLH56_01940)	-	410393..411175 (-)	783	WP_003100105.1	carbon-nitrogen family hydrolase	-
QLH56_RS01945 (QLH56_01945)	-	411566..412258 (+)	693	WP_003100103.1	hypothetical protein	-
QLH56_RS01950 (QLH56_01950)	-	412356..413000 (+)	645	WP_003100102.1	hypothetical protein	-
QLH56_RS01955 (QLH56_01955)	alaS	413128..415746 (-)	2619	WP_003100100.1	alanine--tRNA ligase	-
QLH56_RS01960 (QLH56_01960)	prsA	416044..416985 (-)	942	WP_003100098.1	peptidylprolyl isomerase PrsA	-
QLH56_RS01965 (QLH56_01965)	-	417049..417756 (-)	708	WP_003100096.1	O-methyltransferase	-
QLH56_RS01970 (QLH56_01970)	-	417927..418571 (-)	645	WP_003100094.1	HAD family hydrolase	-
QLH56_RS01975 (QLH56_01975)	-	418607..419260 (-)	654	WP_003100092.1	HAD-IA family hydrolase	-
QLH56_RS01980 (QLH56_01980)	pepF	419262..421064 (-)	1803	WP_003100091.1	oligoendopeptidase F	Regulator
QLH56_RS01985 (QLH56_01985)	-	421090..421788 (-)	699	Protein_392	competence protein CoiA family protein	-
QLH56_RS01990 (QLH56_01990)	-	421921..423026 (+)	1106	WP_089180059.1	IS3 family transposase	-
QLH56_RS01995 (QLH56_01995)	-	423036..423248 (-)	213	WP_003101132.1	competence protein CoiA family protein	-
QLH56_RS02000 (QLH56_02000)	-	423321..424472 (-)	1152	WP_003101130.1	MFS transporter	-
QLH56_RS02005 (QLH56_02005)	-	424547..425263 (-)	717	WP_037583626.1	pseudouridine synthase	-

Sequence

Protein

• Length: 600 a.a.
• Molecular weight: 69719.83 Da
• Isoelectric Point: 5.0039

>NTDB_id=829940 QLH56_RS01980 WP_003100091.1 419262..421064(-) (pepF) [Streptococcus iniae strain DFSM220524]
MSDNRSHLEEKYTWDLSTIFASDRDWEMELNVLVKQVEEAKKWAGHLVESASNLLTITEIELDLSRRIETVYVYAHMKND
QDTTVAKYQEYQAKASALYAKFSEVFSFYEPEFMALEADKFQQFLKEESKLNDYRHFFDKLLHSKKHVLSQAEEELLAGA
QEIFNGAEETFSIFDNADVIFPTVMDDKGQEVEITHGNFISLMESKNRKVRQDAYEGLYSTYEQFQHTYAKTLQTNVKVQ
NFKARVHKYDSARHAAMSANFIPESVYDTLLTAVHKHLPLLHRYLKLRQEILGLNQLKMYDVYTPLSATDLSIPYDQAIE
KAEKVLSIFGDEYAKHVHHAFADRWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDNLDNMFTLVHETGHSLHSTFTRQT
QPYVYGDYSIFLAEIASTTNENILTEALLNEVEDDKERFAILNHYLDGFRGTVFRQTQFAEFEHAIHQADQNGQVLTSEF
LNTLYADLNEKYYGLSKEDNHFIQYEWARIPHFYYNYYVYQYATGFAAASYLANKIVHGEQEDINRYLDYLKAGNSDYPL
NVIAKAGVDMTNETYLNEAFAVFEERLTELEKLVEKGAHL

Nucleotide

• Length: 1803 bp

>NTDB_id=829940 QLH56_RS01980 WP_003100091.1 419262..421064(-) (pepF) [Streptococcus iniae strain DFSM220524]
ATGTCAGATAATCGTAGCCATTTAGAAGAAAAATATACTTGGGATTTAAGCACTATTTTTGCTAGTGATAGAGACTGGGA
AATGGAGCTTAATGTACTTGTTAAGCAAGTAGAAGAAGCTAAAAAATGGGCAGGACATTTAGTAGAGTCTGCTAGTAATT
TATTAACTATTACTGAGATTGAGTTGGACTTGTCACGAAGAATTGAGACTGTCTATGTCTATGCTCATATGAAAAATGAC
CAGGATACTACTGTAGCCAAATATCAAGAATACCAAGCAAAAGCATCGGCTTTATATGCTAAATTTAGTGAAGTCTTTTC
ATTTTATGAACCAGAATTTATGGCACTTGAAGCAGATAAGTTTCAACAATTCCTTAAAGAAGAATCAAAATTAAATGATT
ATAGACATTTCTTTGACAAACTGTTACATAGTAAAAAGCATGTTTTGTCTCAAGCAGAAGAAGAGCTATTGGCTGGTGCA
CAAGAAATTTTTAATGGTGCTGAAGAAACATTTAGTATTTTTGACAATGCCGATGTGATTTTTCCAACAGTTATGGATGA
CAAAGGCCAAGAAGTGGAAATCACGCATGGAAACTTTATCAGTTTGATGGAATCCAAAAACCGTAAGGTGCGTCAAGATG
CTTATGAAGGTCTTTATAGTACCTATGAACAATTCCAACACACTTATGCTAAAACATTGCAAACAAATGTTAAGGTTCAA
AATTTCAAAGCACGTGTTCATAAATATGATTCAGCTCGTCATGCAGCTATGTCAGCAAACTTTATTCCAGAATCTGTTTA
TGATACTCTTCTAACAGCAGTTCATAAGCATTTGCCACTGTTACATCGTTATTTAAAGCTACGCCAGGAAATTCTCGGTC
TTAATCAGTTAAAAATGTATGATGTCTACACGCCACTTTCTGCAACAGATTTATCGATTCCTTATGATCAAGCTATTGAA
AAAGCAGAAAAAGTCTTATCTATTTTTGGTGACGAATATGCTAAACATGTTCATCATGCTTTTGCAGATCGTTGGATTGA
TGTGCATGTTAATAAAGGAAAACGTTCAGGTGCCTATTCAGGTGGTTCATATGATACGAATGCCTTTATGCTCTTGAATT
GGCAAGATAATTTGGATAATATGTTTACTCTGGTTCACGAGACTGGTCATAGTTTACATTCAACCTTTACTCGTCAAACA
CAGCCTTATGTTTATGGTGATTATAGTATTTTCTTGGCGGAGATTGCTTCAACGACTAATGAAAATATTCTGACAGAAGC
TTTATTGAATGAGGTAGAAGACGACAAAGAGCGTTTTGCAATTTTAAATCATTATCTTGATGGTTTCCGTGGAACTGTTT
TCCGTCAGACACAATTTGCTGAATTTGAACATGCTATTCATCAAGCAGATCAAAATGGACAAGTGCTTACAAGTGAATTC
CTTAACACCCTTTATGCTGATTTAAATGAAAAGTATTATGGCTTATCTAAAGAAGACAACCATTTTATTCAATACGAATG
GGCTCGTATTCCTCATTTCTATTACAATTACTATGTTTACCAATATGCAACTGGCTTTGCTGCGGCTAGCTATTTAGCCA
ATAAAATTGTTCATGGTGAGCAAGAAGACATAAACCGTTATTTAGACTATCTTAAAGCTGGAAATTCGGATTACCCATTA
AATGTTATTGCTAAGGCTGGTGTTGATATGACGAATGAGACTTACCTTAACGAAGCATTTGCAGTTTTTGAGGAACGTTT
AACTGAACTTGAAAAACTGGTTGAAAAAGGTGCGCATTTGTAA

Domains

Predicted by InterproScan.

• Oligopeptidase F (Peptidase_M3_N) (112-181)

• Peptidase family M3 (Peptidase_M3) (202-581)

3D structure

• AlphaFold DB: A0A1J0MY34

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pepF	Streptococcus salivarius strain HSISS4	70.667	100	0.707