Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   SIS06_RS21370 Genome accession   NZ_CP139188
Coordinates   4076692..4077381 (-) Length   229 a.a.
NCBI ID   WP_003243527.1    Uniprot ID   P42421
Organism   Bacillus subtilis strain H17-16     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4071692..4082381
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SIS06_RS21350 (SIS06_21350) yxeA 4072597..4072944 (-) 348 WP_003227084.1 YxeA family protein -
  SIS06_RS21355 (SIS06_21355) yxdM 4072958..4074826 (-) 1869 WP_249850747.1 ABC transporter permease YxdM -
  SIS06_RS21360 (SIS06_21360) yxdL 4074801..4075574 (-) 774 WP_014115765.1 ABC transporter ATP-binding protein YxdL -
  SIS06_RS21365 (SIS06_21365) yxdK 4075718..4076695 (-) 978 WP_021481026.1 two-component system sensor histidine kinase YxdK -
  SIS06_RS21370 (SIS06_21370) braR 4076692..4077381 (-) 690 WP_003243527.1 two-component system response regulator YxdJ Regulator
  SIS06_RS21375 (SIS06_21375) iolJ 4077489..4078361 (-) 873 WP_064671730.1 6-phospho-5-dehydro-2-deoxy-D-gluconate aldolase -
  SIS06_RS21380 (SIS06_21380) iolI 4078382..4079218 (-) 837 WP_049140862.1 2-keto-myo-inositol isomerase -
  SIS06_RS21385 (SIS06_21385) iolH 4079304..4080173 (-) 870 WP_064671729.1 sugar phosphate isomerase/epimerase family protein -
  SIS06_RS21390 (SIS06_21390) iolG 4080193..4081227 (-) 1035 WP_003244482.1 bifunctional inositol 2-dehydrogenase/D-chiro-inositol 1-dehydrogenase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26600.34 Da        Isoelectric Point: 4.8564

>NTDB_id=829892 SIS06_RS21370 WP_003243527.1 4076692..4077381(-) (braR) [Bacillus subtilis strain H17-16]
MNKIMIVEDSEDIRGLLQNYLEKYGYQTVVAADFTAVLDVFLREKPDVVLLDINLPAYDGYYWCRQIRQHSTSPIIFISA
RSGEMDQVMAIENGGDDYIEKPFSYDIVLAKIKSQIRRAYGEYAAKQGEKVVEYAGVQLFVERFELRFQDEKSELSKKES
KLLEVLLERGEKVTSRDRLMEKTWDTDIFIDDNTLNVYITRLRKKLRELNAPVSIEAVRGEGYQLRAQS

Nucleotide


Download         Length: 690 bp        

>NTDB_id=829892 SIS06_RS21370 WP_003243527.1 4076692..4077381(-) (braR) [Bacillus subtilis strain H17-16]
TTGAATAAAATCATGATTGTGGAAGACAGTGAAGACATTCGCGGACTATTGCAGAATTACCTTGAAAAATACGGATATCA
AACAGTGGTCGCCGCGGATTTTACAGCTGTTCTTGATGTCTTTTTGCGGGAAAAGCCCGATGTGGTGCTGCTTGATATCA
ATTTGCCGGCATATGACGGATATTATTGGTGCCGGCAGATCCGCCAGCACTCCACAAGCCCGATCATCTTTATTTCTGCC
AGAAGCGGGGAAATGGATCAGGTGATGGCGATTGAAAATGGGGGAGACGATTATATCGAAAAACCGTTTTCTTATGATAT
TGTGCTTGCGAAAATCAAAAGCCAGATCCGGAGGGCGTACGGGGAGTACGCCGCAAAGCAGGGAGAGAAAGTGGTTGAAT
ATGCTGGCGTTCAGCTCTTTGTGGAACGGTTTGAACTGCGTTTTCAGGATGAAAAAAGCGAGCTTTCTAAAAAAGAAAGC
AAGCTTTTGGAAGTGCTGCTTGAGCGGGGAGAAAAGGTGACGAGTCGGGACCGTCTCATGGAAAAGACGTGGGACACCGA
CATATTCATCGATGATAATACACTTAACGTGTATATCACGCGGCTCAGAAAAAAACTGCGGGAGCTGAATGCGCCTGTTT
CTATTGAAGCGGTGCGGGGCGAAGGCTACCAGCTGAGGGCGCAGTCATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-225)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P42421

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

41.704

97.38

0.406