Detailed information NTG0082968

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: H7679_RS10065
• Genome accession: NZ_AP023392
• Coordinates: 2061365..2063818 (-)
• Length: 817 a.a.
• NCBI ID: WP_024395694.1
• Uniprot ID: -
• Organism: Streptococcus suis strain DAT300
• Function: degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 2056365..2068818

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7679_RS10050 (DAT300_19610)	hslO	2058797..2059663 (+)	867	WP_024386123.1	Hsp33 family molecular chaperone HslO	-
H7679_RS10055 (DAT300_19620)	dusB	2059656..2060660 (+)	1005	WP_024395692.1	tRNA dihydrouridine synthase DusB	-
H7679_RS10060 (DAT300_19630)	-	2060755..2061246 (-)	492	WP_024395693.1	adenylyltransferase/cytidyltransferase family protein	-
H7679_RS10065 (DAT300_19640)	clpC	2061365..2063818 (-)	2454	WP_024395694.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
H7679_RS10070 (DAT300_19650)	-	2063822..2064280 (-)	459	WP_002937810.1	CtsR family transcriptional regulator	-
H7679_RS10075 (DAT300_19660)	-	2064551..2064889 (+)	339	WP_024389205.1	thiol reductase thioredoxin	-
H7679_RS10080 (DAT300_19670)	tsf	2065056..2066096 (-)	1041	WP_002937816.1	translation elongation factor Ts	-
H7679_RS10085 (DAT300_19680)	rpsB	2066364..2067140 (-)	777	WP_012775356.1	30S ribosomal protein S2	-

Sequence

Protein

• Length: 817 a.a.
• Molecular weight: 90459.02 Da
• Isoelectric Point: 6.2908

>NTDB_id=82968 H7679_RS10065 WP_024395694.1 2061365..2063818(-) (clpC) [Streptococcus suis strain DAT300]
MKISTGLQRVFEDAQLVAQRYACDYLETWHVLLSFVINHDTVAGAVLAEYPISISDYEHATFVVTDKVYREELDSFRILP
SSKRLDETASFAKKIAEVVKAKELGTEHLFMAMLLDKRSTASQILDKVGFCFEDSDDKFRFLDLRKNLEARAGFTKEDLK
AIRSVMKGGKAKPANMGQMMGMPPAPQSGGLEDYTRDLTALAREGKIEPVIGRDAEIARMIQILSRKTKNNPVLVGDAGV
GKTALTLGLAQRVAAGDVPVSLAKMRVLELDLMNVIAGTRFRGDFEERMNNIINDIEEDGQVILFIDELHTIMGSGSGID
STLDAANILKPALARGTLRTVGATTQTEYQKHIEKDAALVRRFAKVTIEEPTVEDSIAILTGLKGTFEKYHRVRIGQAAV
ETAVTYAKRYLTSKNLPDSAIDLLDEASATVQNRVKGQAEETGLTSIDKALMDKKYKTVSKLLIKTKEDAEASQNYDLEV
TEEDVLETLSRLSGIPVAKLSQSDTKKYLNLEAELHKRVIGQEEAISAVSRAIRRNQSGIRTGRRPIGSFMFLGPTGVGK
TELAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLL
QVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGALDLSKDHKEVEKRIFEELKKAYRPEFINRIDEKVVF
HSLTETHMQDVVKVMIKPLLAITAEKGITLKLQPSALKLLAKQGYDPEMGARPLRRLLQTKLEDPLAEMLLRGDLTTGST
LKVGVKGEELKFDVVKG

Nucleotide

• Length: 2454 bp

>NTDB_id=82968 H7679_RS10065 WP_024395694.1 2061365..2063818(-) (clpC) [Streptococcus suis strain DAT300]
ATGAAAATTTCAACTGGTTTACAGCGGGTTTTTGAAGATGCCCAGTTAGTGGCCCAACGCTATGCTTGTGATTACTTGGA
AACCTGGCATGTTCTCTTGTCTTTCGTTATCAACCATGATACAGTCGCCGGCGCTGTTTTGGCAGAATATCCTATTTCAA
TTTCTGACTATGAACATGCAACTTTTGTTGTGACCGACAAGGTCTATCGTGAAGAGTTGGATAGTTTTCGTATTTTACCA
TCTTCTAAACGTTTGGATGAAACGGCTAGTTTTGCCAAGAAAATTGCAGAAGTCGTCAAGGCTAAGGAGCTGGGAACGGA
ACATTTGTTTATGGCTATGTTGTTGGACAAGCGGTCAACAGCTAGTCAGATTTTGGACAAGGTAGGTTTTTGTTTTGAAG
ACTCAGATGATAAGTTTCGTTTCTTGGATTTGCGTAAAAACTTGGAGGCACGTGCGGGATTTACCAAAGAGGACCTTAAA
GCTATCCGCAGTGTGATGAAGGGGGGCAAAGCCAAACCTGCCAATATGGGACAGATGATGGGAATGCCCCCAGCACCTCA
AAGTGGTGGATTAGAAGACTACACTCGTGATTTGACAGCTTTGGCGCGTGAAGGGAAGATTGAACCTGTTATCGGTCGAG
ACGCTGAGATTGCACGGATGATCCAAATTCTATCACGTAAAACCAAGAACAACCCAGTTCTAGTTGGTGATGCTGGTGTC
GGAAAAACTGCGCTTACTTTGGGTCTTGCTCAACGTGTTGCTGCAGGTGATGTCCCTGTCAGCTTGGCTAAGATGCGGGT
TTTGGAACTTGACTTGATGAACGTTATCGCTGGAACTCGTTTCCGGGGTGATTTCGAAGAGCGGATGAATAATATCATCA
ACGACATTGAGGAAGATGGTCAGGTCATCCTTTTCATCGATGAGTTGCATACCATTATGGGGTCTGGCTCAGGGATTGAT
TCGACCTTGGATGCAGCCAATATCCTCAAACCAGCTCTTGCTCGTGGCACCCTCCGTACAGTCGGAGCAACGACTCAGAC
AGAGTACCAAAAGCATATTGAGAAAGACGCAGCCCTAGTTCGTCGTTTTGCCAAAGTGACCATTGAAGAGCCGACAGTGG
AAGATAGCATTGCCATTTTGACTGGTTTAAAAGGTACTTTTGAAAAATACCACAGGGTCCGTATTGGACAAGCAGCTGTA
GAGACTGCTGTGACCTACGCTAAGCGGTATTTGACCAGTAAAAACCTGCCAGATTCAGCCATTGATCTGCTGGATGAAGC
CAGTGCAACGGTACAAAATCGAGTGAAAGGGCAGGCTGAGGAAACAGGACTGACGAGCATAGACAAGGCCTTGATGGATA
AAAAATATAAGACTGTCAGCAAGCTGTTGATTAAAACGAAAGAAGATGCCGAGGCTAGTCAAAACTATGACCTTGAAGTA
ACAGAAGAAGATGTTTTAGAAACACTTAGCCGCTTGTCAGGTATCCCAGTAGCCAAGCTTAGCCAATCAGATACTAAGAA
GTATCTGAATCTGGAAGCAGAATTGCACAAGCGTGTGATTGGGCAGGAAGAAGCTATTTCTGCAGTTAGCAGAGCTATTC
GCCGTAATCAGTCAGGGATTCGTACAGGTCGCAGACCGATTGGTTCCTTTATGTTCTTGGGACCAACTGGTGTCGGTAAG
ACAGAGCTTGCTAAAGCCTTGGCAGAGGTTCTCTTTGATGATGAATCTGCTCTTATCCGTTTTGATATGTCTGAGTATAT
GGAGAAATTTGCGGCCAGCCGTCTCAATGGAGCGCCTCCAGGTTACGTGGGCTATGAAGAAGGTGGCGAATTGACGGAAA
AAGTTCGTAACAAACCTTATTCTGTTCTTCTTTTTGATGAGGTTGAAAAGGCTCATCCAGATATTTTCAATGTTCTCTTG
CAGGTCTTGGATGATGGTGTTCTGACGGACAGTAAGGGACGTAAGGTTGATTTCTCAAATACTATTATTATCATGACGTC
AAACCTTGGAGCAACAGCCCTTCGTGATGATAAGACAGTTGGTTTTGGTGCCCTTGATTTATCTAAGGACCACAAGGAAG
TGGAGAAACGCATTTTTGAGGAATTGAAAAAAGCCTATCGTCCAGAATTTATCAACCGTATTGACGAGAAAGTTGTCTTC
CATAGCCTAACGGAAACTCATATGCAGGATGTTGTCAAGGTCATGATTAAACCTTTGTTGGCTATAACAGCTGAGAAAGG
AATTACTCTTAAACTGCAACCGTCAGCCCTTAAGTTATTGGCTAAGCAAGGTTATGACCCAGAAATGGGGGCTCGTCCTC
TTCGTAGACTCTTGCAGACCAAGTTGGAAGATCCGTTGGCAGAAATGTTACTCCGTGGTGACTTGACTACTGGTTCGACC
TTGAAGGTTGGGGTTAAGGGTGAAGAGCTCAAGTTTGATGTGGTAAAGGGATAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (372-457)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (102-129)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (14-56)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-803)

• ATPase family associated with various cellular activities (AAA) (AAA) (233-365)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus pneumoniae Rx1	71.779	99.755	0.716
clpC	Streptococcus pneumoniae D39	71.779	99.755	0.716
clpC	Streptococcus pneumoniae TIGR4	71.779	99.755	0.716
clpC	Streptococcus mutans UA159	66.585	99.633	0.663
clpC	Streptococcus thermophilus LMD-9	63.962	100	0.656
clpC	Streptococcus thermophilus LMG 18311	64.38	100	0.655
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.222	100	0.503
clpC	Bacillus subtilis subsp. subtilis str. 168	43.114	100	0.441