Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   SJH97_RS25660 Genome accession   NZ_CP139175
Coordinates   5535128..5535799 (-) Length   223 a.a.
NCBI ID   WP_320587041.1    Uniprot ID   -
Organism   Streptomyces sp. CL7     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5530128..5540799
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SJH97_RS25640 (SJH97_25640) - 5531042..5531251 (+) 210 WP_320587038.1 hypothetical protein -
  SJH97_RS25645 (SJH97_25645) - 5531238..5532629 (+) 1392 WP_320587039.1 amidase -
  SJH97_RS25650 (SJH97_25650) - 5532783..5533358 (+) 576 WP_320587040.1 TetR/AcrR family transcriptional regulator -
  SJH97_RS25655 (SJH97_25655) - 5533618..5534856 (-) 1239 WP_320588473.1 serine hydrolase domain-containing protein -
  SJH97_RS25660 (SJH97_25660) vraR 5535128..5535799 (-) 672 WP_320587041.1 response regulator transcription factor Regulator
  SJH97_RS25665 (SJH97_25665) - 5535786..5536967 (-) 1182 WP_320588474.1 sensor histidine kinase -
  SJH97_RS25670 (SJH97_25670) - 5537139..5537987 (+) 849 WP_320588475.1 oxidoreductase -
  SJH97_RS25675 (SJH97_25675) - 5537987..5538601 (+) 615 WP_320587042.1 TetR/AcrR family transcriptional regulator -
  SJH97_RS25680 (SJH97_25680) - 5538693..5539469 (-) 777 WP_320587043.1 alpha/beta fold hydrolase -
  SJH97_RS25685 (SJH97_25685) - 5539581..5540408 (+) 828 WP_320587044.1 helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 24010.37 Da        Isoelectric Point: 6.7520

>NTDB_id=829573 SJH97_RS25660 WP_320587041.1 5535128..5535799(-) (vraR) [Streptomyces sp. CL7]
MPVAEQISVLVVDDEPVVRAGLSAILDSQSDITVTGTADDGENAVEACARLRPDVLLMDIRMPRRDGLWALAELRRRGLT
GPGRSRVLMLTTFDLDAYVDDALAAGASGFLLKNSSYEELTGAVRAAAAGHSTLSPAVTHRIIEGHLRGRRRPSDHELAR
LSTLTEREADVLCLIRDGLSNAEIAERLVVSLHTVKTHVSRVLTKTGCQSRAQAAVLARNTLS

Nucleotide


Download         Length: 672 bp        

>NTDB_id=829573 SJH97_RS25660 WP_320587041.1 5535128..5535799(-) (vraR) [Streptomyces sp. CL7]
GTGCCGGTGGCTGAGCAGATCAGCGTGCTCGTCGTGGACGACGAGCCGGTCGTCCGCGCCGGGTTGAGCGCCATCCTGGA
CAGTCAGTCGGACATCACCGTGACGGGAACCGCCGACGACGGCGAGAACGCCGTCGAGGCGTGCGCACGGCTCCGGCCGG
ACGTGCTGCTGATGGACATCCGTATGCCGCGCCGCGACGGGCTGTGGGCACTGGCCGAGCTTCGGCGCCGTGGACTGACC
GGGCCGGGGCGCAGCCGGGTGCTCATGCTGACGACGTTCGACCTGGACGCATACGTCGACGACGCGCTCGCCGCCGGGGC
GTCCGGCTTCCTCCTGAAGAACAGTTCGTACGAGGAGCTGACCGGGGCCGTCCGCGCGGCGGCGGCCGGACACAGCACTC
TGAGCCCCGCGGTGACCCACCGGATCATCGAGGGGCATCTCCGTGGCCGGCGGCGCCCCAGCGACCATGAGCTGGCACGG
CTGAGCACCCTCACCGAGCGCGAGGCCGACGTGCTGTGTCTGATCCGCGACGGACTGAGCAACGCCGAGATCGCCGAGCG
GCTCGTGGTGAGCCTGCACACGGTGAAGACACACGTCAGCCGTGTGCTCACGAAGACCGGCTGTCAGAGCAGGGCGCAGG
CTGCTGTGCTGGCCAGGAACACCCTGTCCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(163-218)

Response regulator receiver domain (Response_reg)

(9-124)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.679

95.067

0.368