Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   SJH97_RS25430 Genome accession   NZ_CP139175
Coordinates   5485637..5486272 (+) Length   211 a.a.
NCBI ID   WP_320587010.1    Uniprot ID   -
Organism   Streptomyces sp. CL7     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5480637..5491272
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SJH97_RS25400 (SJH97_25400) - 5480754..5481137 (+) 384 WP_320587005.1 DUF2625 family protein -
  SJH97_RS25405 (SJH97_25405) - 5481138..5481581 (-) 444 WP_320587006.1 Rrf2 family transcriptional regulator -
  SJH97_RS25410 (SJH97_25410) - 5481743..5482213 (+) 471 WP_320587007.1 nuclear transport factor 2 family protein -
  SJH97_RS25415 (SJH97_25415) - 5482457..5483140 (-) 684 WP_320587008.1 ABC transporter ATP-binding protein -
  SJH97_RS25420 (SJH97_25420) - 5483137..5484228 (-) 1092 WP_320588471.1 ABC transporter permease -
  SJH97_RS25425 (SJH97_25425) - 5484420..5485640 (+) 1221 WP_320587009.1 sensor histidine kinase -
  SJH97_RS25430 (SJH97_25430) vraR 5485637..5486272 (+) 636 WP_320587010.1 response regulator transcription factor Regulator
  SJH97_RS25435 (SJH97_25435) - 5486376..5486591 (-) 216 WP_320588472.1 DUF397 domain-containing protein -
  SJH97_RS25440 (SJH97_25440) - 5486607..5487524 (-) 918 Protein_5006 helix-turn-helix domain-containing protein -
  SJH97_RS25445 (SJH97_25445) - 5487741..5489870 (-) 2130 WP_320587011.1 SDR family NAD(P)-dependent oxidoreductase -
  SJH97_RS25450 (SJH97_25450) - 5489926..5490678 (-) 753 WP_320587012.1 TetR/AcrR family transcriptional regulator -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 22006.10 Da        Isoelectric Point: 4.9372

>NTDB_id=829569 SJH97_RS25430 WP_320587010.1 5485637..5486272(+) (vraR) [Streptomyces sp. CL7]
MTDTPIRLLLADDHPVVRAGLRAVLETEEGITVVAEAATAEEAVTRAARDDIDVVLMDLQFGKGMNGAEATAAITARPGS
PRVLIVTTYDTDADTLPAIEAGATGYLLKDAPPEDLAAAVRTAAAGRTTLAPAVADRLLNRLRAPGTALTRRETEVLALV
AEGLSNQAVGDRLHLTEGTVKSHLARVYAKLGVESRTAAVAAAVDLGLIRR

Nucleotide


Download         Length: 636 bp        

>NTDB_id=829569 SJH97_RS25430 WP_320587010.1 5485637..5486272(+) (vraR) [Streptomyces sp. CL7]
GTGACCGACACACCCATCCGTCTGCTCCTGGCCGACGACCACCCCGTCGTACGGGCAGGGCTGCGCGCCGTCCTGGAGAC
CGAGGAGGGCATCACGGTGGTGGCCGAGGCCGCCACCGCCGAAGAAGCCGTCACCCGCGCCGCCCGAGACGACATCGACG
TCGTCCTCATGGATCTCCAGTTCGGCAAGGGCATGAACGGCGCCGAGGCCACCGCCGCCATCACCGCTCGCCCCGGCTCA
CCCCGCGTGCTGATCGTCACCACCTACGACACCGACGCCGACACCCTGCCCGCCATCGAGGCCGGCGCCACCGGCTACCT
CCTCAAGGACGCCCCACCCGAGGACCTGGCCGCCGCCGTACGCACCGCGGCCGCCGGACGCACCACCCTCGCGCCCGCCG
TCGCCGACCGGCTGCTGAACCGGCTACGCGCCCCCGGCACCGCCCTGACCCGTCGCGAGACGGAAGTCCTCGCCCTGGTC
GCGGAGGGCCTGTCCAACCAGGCCGTCGGCGACCGTCTCCACCTGACCGAAGGCACCGTCAAGTCCCACCTGGCCCGCGT
CTACGCCAAGCTCGGTGTCGAATCGCGCACCGCGGCCGTCGCCGCCGCCGTCGACCTCGGCCTCATCCGCCGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(9-120)

Bacterial regulatory proteins, luxR family (GerE)

(148-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.019

98.578

0.365