Detailed information NTG0829546

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: SJH97_RS18605
• Genome accession: NZ_CP139175
• Coordinates: 4011908..4014433 (+)
• Length: 841 a.a.
• NCBI ID: WP_093764606.1
• Uniprot ID: A0ACC6UQC5
• Organism: Streptomyces sp. CL7
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 4006908..4019433

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SJH97_RS18570 (SJH97_18570)	-	4007418..4008215 (+)	798	WP_019526711.1	type III pantothenate kinase	-
SJH97_RS18575 (SJH97_18575)	-	4008328..4008930 (+)	603	WP_320586085.1	hypothetical protein	-
SJH97_RS18580 (SJH97_18580)	-	4008957..4009130 (+)	174	WP_189912634.1	hypothetical protein	-
SJH97_RS18585 (SJH97_18585)	-	4009292..4009699 (+)	408	WP_380809509.1	BlaI/MecI/CopY family transcriptional regulator	-
SJH97_RS18590 (SJH97_18590)	-	4009709..4010242 (+)	534	WP_320586087.1	amino-acid N-acetyltransferase	-
SJH97_RS18595 (SJH97_18595)	-	4010455..4010790 (+)	336	WP_320586088.1	histone-like nucleoid-structuring protein Lsr2	-
SJH97_RS18600 (SJH97_18600)	-	4010769..4011476 (-)	708	WP_320586089.1	SCO3374 family protein	-
SJH97_RS18605 (SJH97_18605)	clpC	4011908..4014433 (+)	2526	WP_093764606.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
SJH97_RS18610 (SJH97_18610)	-	4014497..4017583 (-)	3087	WP_320586090.1	NACHT domain-containing protein	-
SJH97_RS18615 (SJH97_18615)	-	4017649..4018305 (-)	657	WP_320586091.1	HAD family acid phosphatase	-

Sequence

Protein

• Length: 841 a.a.
• Molecular weight: 92985.08 Da
• Isoelectric Point: 5.7484

>NTDB_id=829546 SJH97_RS18605 WP_093764606.1 4011908..4014433(+) (clpC) [Streptomyces sp. CL7]
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKALESLGISLEAVRQQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGADLNRVRQQVIQLLSGYQGKETAAAGGPAEGT
PSTSLVLDQFGRNLTQAARESKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVKGEVPETLKD
KHLYTLDLGALVAGSRYRGDFEERLKKVLKEIRTRGDIILFIDELHTLVGAGAAEGAIDAASILKPMLARGELQTIGATT
LDEYRKHLEKDAALERRFQPIQVAEPSLPHTIEILKGLRDRYEAHHRVSITDEALVQAATLADRYISDRFLPDKAIDLID
EAGSRMRIRRMTAPPDLREFDEKIAGVRRDKESAIDSQDFEKAASLRDKEKQLLAAKAKREKEWKAGDMDVVAEVDGELI
AEVLATATGIPVFKLTEEESSRLLRMEEELHKRVIGQDDAVKALSKAIRRTRAGLKDPKRPGGSFIFAGPSGVGKTELSK
ALAEFLFGDEDALISLDMSEFSEKHTVSRLFGSPPGYVGYEEGGQLTEKVRRKPFSVVLFDEVEKAHPDIFNSLLQILED
GRLTDSQGRVVDFKNTVIIMTTNLGTRDISKGFNLGFAAAGDTKTNYERMKNKVSDELKQHFRPEFLNRVDDVVVFPQLT
QGDILRIVDLMIDKVDERLKDRDMGIELSQSAKELLSKKGYDPVLGARPLRRTIQREIEDSLSEKILFGELRPGHIVVVD
TEGEGENQTFTFRGEEKSALPDVPPIEQAAGGAGPNLSKDA

Nucleotide

• Length: 2526 bp

>NTDB_id=829546 SJH97_RS18605 WP_093764606.1 4011908..4014433(+) (clpC) [Streptomyces sp. CL7]
ATGTTCGAGAGGTTCACCGACCGCGCGCGGCGGGTTGTCGTCCTGGCTCAGGAAGAAGCCCGGATGCTCAACCACAACTA
CATCGGCACCGAGCACATCCTCCTGGGCCTGATCCACGAGGGTGAGGGTGTCGCCGCCAAGGCCCTTGAGAGCCTCGGGA
TTTCGCTCGAGGCGGTCCGCCAGCAGGTGGAGGAGATCATCGGGCAGGGCCAGCAGGCCCCGTCGGGTCACATCCCCTTC
ACCCCCCGTGCCAAGAAGGTCCTGGAGCTGTCGCTCCGCGAGGCCCTTCAGCTGGGCCACAACTACATCGGCACGGAGCA
CATCCTGCTCGGCCTGATCCGTGAGGGCGAGGGCGTCGCCGCCCAGGTCCTGGTCAAGCTGGGCGCTGATCTGAACCGCG
TGCGGCAGCAGGTGATCCAGCTGCTCTCCGGTTACCAGGGCAAGGAGACCGCCGCCGCCGGCGGGCCTGCCGAGGGCACC
CCCTCGACGTCCCTGGTCCTCGACCAGTTCGGCCGGAACCTCACCCAGGCCGCTCGTGAGTCCAAGCTCGACCCGGTCAT
CGGGCGCGAGAAGGAGATCGAGCGGGTCATGCAGGTGCTGTCCCGCCGTACCAAGAACAACCCGGTGCTGATCGGTGAGC
CCGGCGTCGGCAAGACCGCCGTCGTCGAGGGCCTCGCCCAGGCGATCGTCAAGGGCGAGGTGCCCGAGACCCTCAAGGAC
AAGCACCTCTACACCCTGGACCTCGGCGCCCTGGTGGCCGGCTCCCGCTACCGCGGTGACTTCGAGGAGCGCCTGAAGAA
GGTGCTCAAGGAGATCCGCACCCGCGGCGACATCATCCTGTTCATCGACGAGCTGCACACGCTGGTCGGTGCGGGCGCCG
CCGAGGGCGCGATCGACGCGGCGAGCATCCTCAAGCCGATGCTGGCCCGCGGCGAGCTCCAGACCATCGGTGCGACCACG
CTGGACGAGTACCGCAAGCACCTGGAGAAGGACGCGGCCCTCGAGCGCCGCTTCCAGCCCATCCAGGTCGCCGAGCCGTC
CCTGCCGCACACGATCGAGATCCTCAAGGGTCTGCGCGACCGCTACGAGGCGCACCACCGCGTCTCCATCACGGACGAGG
CGCTGGTCCAGGCCGCCACCCTGGCCGACCGCTACATCTCGGACCGCTTCCTGCCGGACAAGGCGATCGACCTGATCGAC
GAGGCCGGTTCCCGGATGCGCATCCGCCGGATGACCGCGCCGCCGGACCTGCGCGAGTTCGACGAGAAGATCGCCGGTGT
CCGCCGCGACAAGGAGTCCGCGATCGACTCGCAGGACTTCGAGAAGGCCGCCTCGCTGCGCGACAAGGAGAAGCAGCTCC
TGGCCGCCAAGGCGAAGCGGGAGAAGGAGTGGAAGGCCGGCGACATGGACGTCGTCGCCGAGGTCGACGGCGAGCTGATC
GCCGAGGTCCTCGCGACCGCCACCGGCATCCCCGTCTTCAAGCTGACCGAGGAGGAGTCCAGCCGCCTGCTCCGCATGGA
GGAGGAGCTGCACAAGCGGGTCATCGGCCAGGACGACGCCGTCAAGGCGCTGTCCAAGGCGATCCGCCGTACCCGCGCCG
GTCTGAAGGACCCGAAGCGTCCGGGTGGCTCGTTCATCTTCGCCGGTCCGTCCGGTGTCGGTAAGACGGAGCTGTCCAAG
GCGCTCGCGGAGTTCCTCTTCGGTGACGAGGACGCGCTGATCTCCCTCGACATGTCGGAGTTCAGCGAGAAGCACACGGT
GTCGCGTCTCTTCGGTTCGCCCCCCGGTTACGTGGGCTACGAGGAGGGCGGCCAGCTGACGGAGAAGGTGCGCCGCAAGC
CGTTCTCGGTCGTCCTCTTCGACGAGGTCGAGAAGGCCCACCCGGACATCTTCAACTCGCTGCTGCAGATCCTGGAGGAC
GGTCGGCTGACCGACTCCCAGGGCCGGGTCGTGGACTTCAAGAACACGGTCATCATCATGACGACCAACCTCGGCACCCG
GGACATCTCCAAGGGCTTCAACCTGGGCTTCGCCGCCGCGGGCGACACGAAGACCAACTACGAGCGCATGAAGAACAAGG
TCTCGGACGAGCTCAAGCAGCACTTCCGGCCCGAGTTCCTCAACCGTGTCGACGACGTGGTGGTCTTCCCGCAGCTGACC
CAGGGCGACATCCTGCGGATCGTCGACCTGATGATCGACAAGGTGGACGAGCGTCTGAAGGACCGGGACATGGGCATCGA
GCTCTCCCAGTCCGCCAAGGAGCTGCTGTCCAAGAAGGGCTACGACCCCGTTCTGGGCGCCCGGCCGCTGCGCCGGACCA
TCCAGCGGGAGATCGAGGACTCGCTGTCGGAGAAGATCCTCTTCGGCGAGCTGCGTCCCGGTCACATCGTGGTCGTGGAC
ACCGAGGGCGAGGGCGAGAACCAGACCTTCACCTTCCGTGGCGAGGAGAAGTCGGCCCTGCCCGACGTCCCGCCGATCGA
GCAGGCGGCCGGCGGCGCCGGTCCGAACCTGAGCAAGGACGCGTAA

Domains

Predicted by InterProScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (209-329)

• AAA domain (Cdc48 subfamily) (AAA_2) (541-712)

• AAA lid domain (AAA_lid_9) (349-449)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (719-799)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (93-142)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (16-68)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	61.845	95.363	0.59
clpC	Streptococcus mutans UA159	44.337	98.692	0.438
clpC	Streptococcus thermophilus LMG 18311	42.738	99.881	0.427
clpC	Streptococcus thermophilus LMD-9	43.168	98.335	0.424
clpC	Streptococcus pneumoniae Rx1	44.334	95.482	0.423
clpC	Streptococcus pneumoniae D39	44.334	95.482	0.423
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.827	96.314	0.422
clpC	Streptococcus pneumoniae TIGR4	44.361	94.887	0.421
clpE	Streptococcus mutans UA159	54.313	74.435	0.404
clpE	Streptococcus pneumoniae TIGR4	53.291	74.078	0.395
clpE	Streptococcus pneumoniae R6	53.13	74.078	0.394
clpE	Streptococcus pneumoniae D39	53.13	74.078	0.394
clpE	Streptococcus pneumoniae Rx1	53.13	74.078	0.394
clpC	Lactococcus lactis subsp. cremoris KW2	53.226	73.722	0.392