Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   R9806_RS10750 Genome accession   NZ_CP139044
Coordinates   2689644..2690315 (+) Length   223 a.a.
NCBI ID   WP_320589819.1    Uniprot ID   -
Organism   Streptomyces sp. KN37     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2684644..2695315
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R9806_RS10735 (R9806_10735) - 2685842..2687062 (+) 1221 WP_320589816.1 Rossmann fold nucleotide-binding protein -
  R9806_RS10740 (R9806_10740) - 2687059..2688210 (-) 1152 WP_320589817.1 glycosyltransferase family 4 protein -
  R9806_RS10745 (R9806_10745) - 2688352..2689581 (+) 1230 WP_320589818.1 sensor histidine kinase -
  R9806_RS10750 (R9806_10750) vraR 2689644..2690315 (+) 672 WP_320589819.1 response regulator transcription factor Regulator
  R9806_RS10755 (R9806_10755) - 2690406..2691485 (-) 1080 WP_320589820.1 ABC transporter ATP-binding protein -
  R9806_RS10760 (R9806_10760) - 2691485..2693173 (-) 1689 WP_223777051.1 ABC transporter permease -
  R9806_RS10765 (R9806_10765) - 2693149..2694228 (-) 1080 WP_223777050.1 thiamine ABC transporter substrate binding subunit -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 23808.44 Da        Isoelectric Point: 6.3451

>NTDB_id=829185 R9806_RS10750 WP_320589819.1 2689644..2690315(+) (vraR) [Streptomyces sp. KN37]
MIRTLVADDQAVVRTGFVNLLGTQDDIQVVAEAEDGAQAVRLAAEHRPDLVLLDIRMPHKNGIDAAREILAASGGATKAL
MLTTFGLDEYVYEALTAGASGFLLKDATFPELLHAVRVVAAGNALLSPEITKRLVAEFTRQRAAVPPVPAGGVDGLTARE
VEVLVLIAQGLSNAEIADRLTITDHTVKTHINRLFTKMGLRDRAQAVILAYERGLVRAAAARS

Nucleotide


Download         Length: 672 bp        

>NTDB_id=829185 R9806_RS10750 WP_320589819.1 2689644..2690315(+) (vraR) [Streptomyces sp. KN37]
GTGATCAGAACCCTCGTCGCGGACGATCAGGCCGTCGTGCGCACCGGTTTCGTGAACCTCCTGGGCACCCAGGACGACAT
CCAGGTCGTCGCCGAGGCCGAGGACGGCGCCCAGGCCGTCCGCCTCGCGGCCGAGCACCGCCCCGACCTGGTCCTGCTCG
ACATCCGTATGCCGCACAAGAACGGCATCGACGCGGCCCGCGAGATCCTCGCGGCGTCCGGCGGCGCGACGAAGGCGCTG
ATGCTGACGACGTTCGGCCTCGACGAGTACGTGTACGAGGCGCTGACCGCCGGGGCCTCGGGGTTTCTGCTCAAGGACGC
GACGTTCCCCGAACTGCTGCACGCGGTACGGGTCGTGGCGGCGGGCAACGCCCTGCTGTCGCCAGAGATCACCAAGCGTC
TCGTCGCCGAGTTCACGCGCCAGCGGGCCGCCGTCCCCCCGGTTCCCGCGGGCGGCGTCGACGGGCTGACGGCCCGTGAG
GTGGAGGTGCTCGTCCTCATCGCGCAGGGCCTGTCGAACGCGGAGATCGCCGACCGCCTCACGATCACCGACCACACCGT
GAAGACGCACATCAACCGCCTCTTCACCAAGATGGGGCTGCGCGACCGGGCGCAGGCGGTGATCCTCGCGTACGAACGGG
GACTGGTGAGGGCCGCGGCGGCGCGGAGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(155-210)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.963

96.861

0.368