Detailed information NTG0082914

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: H7677_RS09105
• Genome accession: NZ_AP023391
• Coordinates: 1867870..1870323 (-)
• Length: 817 a.a.
• NCBI ID: WP_172079098.1
• Uniprot ID: -
• Organism: Streptococcus suis strain DAT299
• Function: degradation of ComW (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	1866156..1876149	1867870..1870323	within	0

Gene organization within MGE regions

Location: 1866156..1876149

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7677_RS09095 (DAT299_17600)	dusB	1866156..1867160 (+)	1005	WP_184493492.1	tRNA dihydrouridine synthase DusB	-
H7677_RS09100 (DAT299_17610)	-	1867261..1867752 (-)	492	WP_172059804.1	adenylyltransferase/cytidyltransferase family protein	-
H7677_RS09105 (DAT299_17620)	clpC	1867870..1870323 (-)	2454	WP_172079098.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
H7677_RS09110 (DAT299_17630)	-	1870327..1870785 (-)	459	WP_002937810.1	CtsR family transcriptional regulator	-
H7677_RS09115 (DAT299_17640)	-	1871056..1871394 (+)	339	WP_029751962.1	thiol reductase thioredoxin	-
H7677_RS09120 (DAT299_17650)	-	1871641..1872261 (-)	621	WP_184493494.1	Spy0128 family protein	-
H7677_RS09125 (DAT299_17660)	srtB	1872298..1872924 (-)	627	WP_232088975.1	class B sortase	-
H7677_RS09130 (DAT299_17670)	-	1873022..1874053 (-)	1032	WP_184493496.1	QVPTGV class sortase B protein-sorting domain-containing protein	-
H7677_RS09135 (DAT299_17680)	lepB	1874074..1874616 (-)	543	WP_079739264.1	signal peptidase I	-
H7677_RS09140 (DAT299_17690)	-	1874623..1876149 (-)	1527	WP_184493498.1	Cys-Gln thioester bond-forming surface protein	-

Sequence

Protein

• Length: 817 a.a.
• Molecular weight: 90466.95 Da
• Isoelectric Point: 6.2908

>NTDB_id=82914 H7677_RS09105 WP_172079098.1 1867870..1870323(-) (clpC) [Streptococcus suis strain DAT299]
MKISTGLQRVFEDAQLVAQRYACDYLETWHVLLSFVINHDTVAGAVLAEYPISISDYEHATFVVTDKVYREELDSFRILP
SSKRLDETASFAKKIAEGVKAKELGTEHLFMAMLLDKRSTASQILDKVGFCFEDSDDKFRFLDLRKNLEARAGFTKEDLK
AIRSVMKGGKAKPTNMGQMMGMPPAPQSGGLEDYTRDLTALAREGKIEPVIGRDAEIARMIQILSRKTKNNPVLVGDAGV
GKTALALGLAQRVAAGDVPVSLAKMRVLELDLMNVIAGTRFRGDFEERMNNIINDIEEDGQVILFIDELHTIMGSGSGID
STLDAANILKPALARGTLRTVGATTQTEYQKHIEKDAALVRRFAKVTIEEPTVEDSIAILTGLKGTFEKYHRVRIGQAAV
ETAVTYAKRYLTSKNLPDSAIDLLDEASATVQNRVKGQAEETGLTSIDKALMDKKYKTVSKLLIKTKEDAEASQNYDLEV
TEEDVLETLSRLSGIPVAKLSQSDTKKYLNLEAELHKRVIGQEEAISAVSRAIRRNQSGIRTGRRPIGSFMFLGPTGVGK
TELAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLL
QVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAFDLSKDHKEVEKRIFEELKKAYRPEFINRIDEKVVF
HSLTETHMQDVVKVMIKPLLAVTAEKGITLKLQPSALKLLAKQGYDPEMGARPLRRLLQTKLEDPLAEMLLRGDLTTSST
LKVGVKGEELKFDVVKG

Nucleotide

• Length: 2454 bp

>NTDB_id=82914 H7677_RS09105 WP_172079098.1 1867870..1870323(-) (clpC) [Streptococcus suis strain DAT299]
ATGAAAATTTCAACTGGTTTACAGCGGGTTTTTGAAGATGCCCAGTTAGTGGCCCAACGTTATGCCTGTGATTACTTGGA
AACCTGGCATGTTCTCTTGTCTTTCGTTATCAACCATGATACAGTCGCTGGCGCTGTTTTGGCAGAATATCCTATTTCAA
TTTCTGACTATGAACATGCAACTTTTGTTGTGACCGACAAGGTCTATCGTGAAGAGTTGGATAGTTTTCGTATTTTACCA
TCTTCTAAACGTTTGGATGAAACAGCTAGTTTTGCCAAGAAAATTGCAGAAGGCGTCAAGGCTAAGGAGCTGGGAACGGA
ACATTTGTTTATGGCTATGTTGTTGGACAAGCGGTCAACAGCTAGTCAGATTTTGGACAAGGTAGGTTTTTGTTTTGAAG
ACTCAGATGATAAGTTTCGTTTCTTGGATTTGCGTAAAAACTTGGAGGCACGTGCGGGATTTACCAAAGAGGACCTTAAA
GCTATCCGCAGTGTGATGAAGGGTGGCAAAGCCAAACCTACTAATATGGGACAGATGATGGGAATGCCCCCAGCACCTCA
AAGTGGTGGATTAGAAGACTACACTCGTGATTTGACAGCTTTGGCGCGTGAAGGGAAGATTGAACCTGTCATCGGTCGAG
ACGCTGAGATTGCACGGATGATCCAAATTCTATCACGTAAAACCAAGAACAACCCAGTTCTAGTTGGTGATGCTGGTGTC
GGAAAAACTGCGCTTGCTTTGGGTCTTGCTCAACGTGTTGCTGCAGGTGATGTCCCTGTCAGCTTGGCTAAGATGCGGGT
TTTGGAACTTGACTTGATGAACGTTATCGCTGGAACTCGTTTCCGGGGTGATTTCGAAGAGCGGATGAATAATATCATCA
ACGACATCGAGGAAGATGGTCAGGTCATCCTTTTTATCGATGAGTTGCATACCATTATGGGTTCTGGCTCAGGGATTGAT
TCGACCTTGGATGCAGCCAATATCCTCAAACCAGCTCTTGCTCGTGGCACCCTCCGTACGGTCGGAGCGACGACTCAGAC
AGAGTACCAAAAGCATATTGAGAAAGACGCAGCCCTGGTTCGTCGTTTTGCCAAAGTGACCATTGAAGAGCCGACAGTGG
AAGATAGCATTGCCATTTTGACTGGTTTAAAAGGTACTTTTGAAAAATACCACAGGGTCCGTATTGGACAAGCAGCTGTA
GAGACTGCTGTGACCTACGCTAAGCGGTATTTGACCAGTAAAAACCTGCCAGATTCTGCCATTGATTTGCTGGATGAAGC
CAGTGCAACGGTACAAAATCGAGTGAAAGGGCAGGCTGAGGAAACAGGACTGACGAGCATAGACAAGGCCTTGATGGATA
AAAAATATAAGACTGTCAGCAAGCTTTTGATTAAAACGAAAGAAGATGCCGAGGCTAGTCAAAACTATGACCTTGAAGTA
ACAGAAGAAGATGTTTTAGAAACACTTAGCCGCTTGTCAGGTATCCCAGTAGCCAAGCTTAGCCAATCAGATACTAAGAA
GTATCTGAATCTGGAAGCAGAATTGCACAAGCGTGTGATTGGGCAGGAAGAAGCTATTTCTGCAGTTAGCAGAGCTATTC
GCCGTAATCAGTCAGGGATTCGTACAGGTCGCAGACCGATTGGTTCCTTTATGTTCTTGGGACCAACTGGTGTCGGTAAG
ACAGAGCTTGCTAAAGCCTTGGCAGAGGTTCTCTTTGATGATGAATCTGCTCTTATCCGTTTTGATATGTCCGAGTATAT
GGAGAAATTTGCGGCCAGCCGTCTCAATGGAGCGCCTCCAGGTTACGTGGGCTATGAAGAAGGTGGCGAATTGACAGAAA
AAGTTCGTAACAAACCTTATTCTGTTCTTCTTTTTGATGAGGTTGAAAAGGCTCATCCAGATATTTTCAATGTTCTCTTG
CAGGTCTTGGATGATGGTGTTCTGACGGACAGTAAGGGACGTAAGGTTGATTTCTCAAATACTATTATTATCATGACGTC
AAACCTTGGAGCAACAGCTCTTCGTGATGATAAGACAGTTGGTTTTGGTGCCTTTGATTTATCTAAGGACCACAAGGAAG
TGGAGAAACGCATTTTTGAGGAATTGAAAAAAGCCTATCGTCCAGAATTTATCAACCGTATTGACGAGAAAGTTGTCTTC
CATAGCCTAACGGAAACTCATATGCAGGATGTTGTCAAGGTCATGATTAAACCTTTGTTGGCTGTAACAGCTGAGAAAGG
AATTACTCTTAAACTGCAACCGTCAGCCCTTAAGTTATTGGCTAAACAAGGTTATGACCCAGAAATGGGGGCTCGTCCGC
TACGTAGGCTCTTACAAACCAAATTGGAAGATCCGTTGGCAGAAATGTTACTCCGTGGTGACTTGACTACTAGTTCGACC
TTGAAGGTTGGGGTCAAGGGTGAAGAGCTCAAGTTTGATGTGGTAAAGGGATAA

Domains

Predicted by InterproScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (94-129)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (14-56)

• ATPase family associated with various cellular activities (AAA) (AAA) (233-365)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-802)

• AAA lid domain (AAA_lid_9) (372-457)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus pneumoniae Rx1	71.656	99.755	0.715
clpC	Streptococcus pneumoniae D39	71.656	99.755	0.715
clpC	Streptococcus pneumoniae TIGR4	71.656	99.755	0.715
clpC	Streptococcus mutans UA159	66.462	99.633	0.662
clpC	Streptococcus thermophilus LMD-9	63.723	100	0.654
clpC	Streptococcus thermophilus LMG 18311	64.14	100	0.652
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.102	100	0.502
clpC	Bacillus subtilis subsp. subtilis str. 168	43.097	100	0.439