Detailed information NTG0082906

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: H7677_RS07635
• Genome accession: NZ_AP023391
• Coordinates: 1564662..1565711 (-)
• Length: 349 a.a.
• NCBI ID: WP_004194592.1
• Uniprot ID: A0A0N0DPM5
• Organism: Streptococcus suis strain DAT299
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1559662..1570711

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7677_RS07615 (DAT299_14640)	nadE	1560538..1561362 (+)	825	WP_184493309.1	ammonia-dependent NAD(+) synthetase	-
H7677_RS07620 (DAT299_14650)	-	1562188..1562715 (-)	528	WP_002942846.1	VanZ family protein	-
H7677_RS07625 (DAT299_14660)	rlmN	1562712..1563824 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
H7677_RS07630 (DAT299_14670)	-	1563833..1564474 (-)	642	WP_184493311.1	YutD family protein	-
H7677_RS07635 (DAT299_14680)	sepM	1564662..1565711 (-)	1050	WP_004194592.1	SepM family pheromone-processing serine protease	Regulator
H7677_RS07640 (DAT299_14690)	coaD	1565698..1566186 (-)	489	WP_002939048.1	pantetheine-phosphate adenylyltransferase	-
H7677_RS07645 (DAT299_14700)	rsmD	1566176..1566715 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
H7677_RS07650 (DAT299_14710)	-	1567013..1567735 (-)	723	WP_184493313.1	serine protease	-
H7677_RS07655 (DAT299_14720)	-	1567792..1568178 (-)	387	WP_044678746.1	rhodanese-like domain-containing protein	-
H7677_RS07660 (DAT299_14730)	-	1568178..1568396 (-)	219	WP_004194736.1	YqgQ family protein	-
H7677_RS07665 (DAT299_14740)	-	1568704..1569306 (-)	603	WP_024413996.1	response regulator transcription factor	-
H7677_RS07670 (DAT299_14750)	-	1569303..1570397 (-)	1095	WP_184493315.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37747.80 Da
• Isoelectric Point: 4.6112

>NTDB_id=82906 H7677_RS07635 WP_004194592.1 1564662..1565711(-) (sepM) [Streptococcus suis strain DAT299]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSVPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=82906 H7677_RS07635 WP_004194592.1 1564662..1565711(-) (sepM) [Streptococcus suis strain DAT299]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATTTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAAGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAAACTTCGCAAAATATGGCGAAGTATCAAGGATTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGAATAGGCATCACTCTCGTAG
ACCATACAGAGGTTCAAAGTTCGGTTCCAATTGATTTCCAAACGGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACGAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A0N0DPM5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605