Detailed information NTG0082887

Bioinformatically predicted

Overview

• Name: uvrA
• Type: Machinery gene
• Locus tag: R8611_RS00965
• Genome accession: NZ_AP026927
• Coordinates: 184576..187407 (+)
• Length: 943 a.a.
• NCBI ID: WP_044811357.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700178
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 179576..192407

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8611_RS00940 (PC0174_01790)	-	180145..180708 (+)	564	WP_000166586.1	DNA-3-methyladenine glycosylase I	-
R8611_RS00945 (PC0174_01800)	-	180705..181382 (+)	678	WP_000987422.1	CPBP family intramembrane glutamic endopeptidase	-
R8611_RS00950 (PC0174_01810)	-	181519..182550 (-)	1032	WP_000255109.1	S66 peptidase family protein	-
R8611_RS00955 (PC0174_01820)	-	182805..183488 (-)	684	WP_000078022.1	DUF1129 domain-containing protein	-
R8611_RS00960 (PC0174_01830)	-	183500..184444 (-)	945	WP_000815629.1	magnesium transporter CorA family protein	-
R8611_RS00965 (PC0174_01840)	uvrA	184576..187407 (+)	2832	WP_044811357.1	excinuclease ABC subunit UvrA	Machinery gene
R8611_RS00970 (PC0174_01850)	-	187400..188461 (+)	1062	WP_050199380.1	Xaa-Pro peptidase family protein	-
R8611_RS00975 (PC0174_01860)	spx	188593..188991 (+)	399	WP_000591165.1	transcriptional regulator Spx	-
R8611_RS00980 (PC0174_01870)	-	189057..189626 (+)	570	WP_000725141.1	SP0191 family lipoprotein	-
R8611_RS00985 (PC0174_01880)	-	189713..189979 (+)	267	WP_000507059.1	IreB family regulatory phosphoprotein	-
R8611_RS00990 (PC0174_01890)	ruvX	189983..190402 (+)	420	WP_001808830.1	Holliday junction resolvase RuvX	-
R8611_RS00995 (PC0174_01900)	-	190418..190723 (+)	306	WP_000017620.1	DUF1292 domain-containing protein	-
R8611_RS01000 (PC0174_01910)	-	190981..192231 (+)	1251	WP_000464307.1	folylpolyglutamate synthase/dihydrofolate synthase family protein	-

Sequence

Protein

• Length: 943 a.a.
• Molecular weight: 104257.46 Da
• Isoelectric Point: 6.4180

>NTDB_id=82887 R8611_RS00965 WP_044811357.1 184576..187407(+) (uvrA) [Streptococcus pneumoniae strain PZ900700178]
MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGL
SPAISIDQKTTSKNPRSTVGTTTEINDYLRLLYARVGTPYCINGHGAIKASSVEQIVDKVLELPERQRLQILAPVIRKKK
GQHKSVIEKIQKDGYVRVRVDGEVYDVTEVLELSKSRQHNIDVVVDRIVIKEGIRSRLFDSIEAALRIAEGYVIIDTMDD
SELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCSECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNML
EQAMKVFGVAMDKPFEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYTRTQMRLYM
NELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTLSENEAIIARPILKEIKDRLTFLNNVGLNYL
TLSRSAGTLSGGESQRIRLATQIGSNLSGVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLI
DVGPGAGVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNLQNVTARFPLGKFIAVT
GVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHVDRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNE
AKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVEFF
QHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYILDEPTTGLHTEDIARLLKVLARFVD
DGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGTIIVTGTPEEVAANEASYTGHYLKGKLHHE

Nucleotide

• Length: 2832 bp

>NTDB_id=82887 R8611_RS00965 WP_044811357.1 184576..187407(+) (uvrA) [Streptococcus pneumoniae strain PZ900700178]
ATGCAAGATAAAATTGTCATTCATGGGGCGCGTGCCCATAATTTAAAAAATATTGATGTGGAGATTCCGCGAGACAAGTT
GGTTGTCGTGACTGGCTTGTCAGGTTCAGGGAAGTCCAGTCTGGCTTTTGATACCCTCTATGCGGAGGGACAACGTCGCT
ATGTAGAGAGTTTGTCCGCCTACGCTCGTCAGTTCTTGGGAAATATGGAAAAACCAGATGTAGATGCCATTGATGGTCTC
AGCCCAGCTATTTCTATCGACCAGAAAACGACTAGCAAAAACCCTCGCTCGACGGTGGGAACAACGACTGAAATCAATGA
CTATCTGCGTCTCCTCTACGCGCGTGTGGGGACGCCTTACTGTATCAACGGGCATGGGGCTATCAAGGCTTCTTCTGTGG
AGCAAATCGTTGATAAGGTTTTGGAGTTACCTGAACGCCAGCGCCTGCAGATTTTGGCCCCTGTCATCCGTAAGAAAAAA
GGACAGCATAAGAGCGTTATCGAGAAGATTCAGAAAGATGGGTATGTTCGTGTCCGTGTGGATGGGGAAGTCTATGATGT
GACCGAAGTGCTAGAGTTGTCCAAGAGCAGACAACACAATATTGATGTCGTAGTTGACCGTATTGTCATCAAGGAGGGTA
TTCGTAGCCGTCTCTTTGATTCCATTGAAGCTGCCCTTCGTATTGCAGAAGGTTATGTCATTATCGACACCATGGACGAT
TCGGAGTTGCTCTTCTCTGAGCATTATGCCTGTCCAGTTTGTGGTTTTACTGTCCCAGAGTTAGAGCCTCGTCTCTTCTC
TTTCAATGCTCCTTTTGGCTCTTGTAGTGAGTGTGACGGCTTGGGCATCAAGCTGGAGGTGGATACTGATTTGGTAGTGC
CAGATGCCAGCAAAACCTTACGTGAGGGAGCGCTAGCACCTTGGAATCCTATCTCATCCAACTACTATCCAAACATGTTA
GAGCAGGCCATGAAAGTCTTTGGAGTGGCTATGGATAAGCCTTTTGAGGACCTGTCAGAAGAAGATAAGAACTTGATTCT
CTATGGGTCAGATGGTAAGGAATTCCATTTCCACTATGAGAATGAATTTGGTGGCGTGCGCGATATCGACATTCCGTTTG
AGGGAGTTATCAATAATATCAAACGTCGTTACCATGAAACCAATAGCGATTACACTCGCACTCAGATGCGTCTCTACATG
AATGAGCTGACCTGCGGAACCTGTCAAGGCTATCGTCTCAATGACCAGGCCTTGTCTGTCCGTGTGGGCGGCCAGCAAGG
GCCACATATTGGAGAAATCTCAGACCTGTCTATCGCTGACCACTTGGACTTGGTGAGCCAGTTAACTTTGTCTGAAAATG
AAGCCATCATTGCTCGTCCCATTCTCAAGGAAATCAAGGATCGTTTGACCTTCCTTAATAATGTGGGTCTTAACTATCTA
ACCCTGTCACGTTCAGCAGGAACCCTTTCAGGTGGGGAAAGTCAGCGCATTCGTTTGGCAACCCAGATTGGTTCCAACCT
ATCAGGCGTCCTCTATATCCTAGACGAGCCGTCAATCGGTCTTCACCAGAGGGACAATGACCGCCTGATTGCCAGTCTGA
AAAAGATGCGTGACTTGGGCAATACTCTTATCGTGGTGGAACACGACGAAGATACCATGCGTGAAGCTGATTATCTGATT
GACGTTGGTCCTGGTGCCGGTGTTTTTGGTGGTGAGATTGTTGCAGCAGGTACACCTAAGCAAGTGGCTCGCAACAGCAA
GTCTATCACAGGTCAGTACTTGTCAGGCAAACGTGTCATCCCAGTACCAGAAGAGCGCCGTGTCGGAAATGGTCGTTTTA
TTGAAGTGATAGGAGCGCGTGAGAACAACTTGCAAAATGTCACGGCTCGCTTTCCACTAGGAAAATTTATCGCAGTGACA
GGTGTGTCGGGTTCAGGGAAATCGACTCTAATCAACAGCATTCTCAAAAAAGCCATTGCCCAGAAGCTCAACCGTAATTC
AGACAAACCTGGTAAGTTTAAGACTATTACAGGGATTGAGCATGTCGACCGTTTGATTGATATTGACCAGAGCCCTATCG
GACGGACGCCGAGGTCTAACCCAGCTACCTATACAGGAGTTTTTGACGATATACGTGACCTTTTTGCTCAGACAAATGAA
GCCAAGATTCGAGGCTACAAGAAGGGGCGCTTCAGTTTCAACGTCAAGGGAGGTCGCTGTGAAGCTTGCTCAGGTGACGG
GATTATCAAGATTGAGATGCACTTCTTGCCAGATGTTTATGTGGCTTGTGAAGTTTGCCACGGAACCCGCTATAACAGTG
AAACCCTAGAAGTTCACTACAAGGAAAAGAATATTTCGCAGGTCTTGGATATGACGGTCAACGATGCGGTAGAATTTTTC
CAACACATTCCGAAAATTCAACGCAAACTCCAGACCATCAAGGATGTAGGTCTAGGCTATGTGACCTTGGGACAGCCAGC
TACCACCCTTTCTGGGGGAGAAGCCCAACGTATGAAGTTAGCTAGCGAACTCCACAAACGCTCGACAGGAAAATCTTTCT
ACATTCTGGATGAGCCGACGACAGGGCTTCATACAGAGGACATTGCTCGCCTGCTCAAGGTTTTAGCTCGCTTTGTAGAC
GACGGCAATACAGTCCTCGTCATCGAGCACAATCTGGATGTTATCAAGACGGCAGACCATATCATTGACTTGGGACCTGA
GGGCGGTGTCGGTGGTGGAACCATCATCGTAACAGGAACTCCAGAAGAAGTAGCTGCCAACGAAGCCAGCTATACAGGAC
ACTATTTGAAAGGAAAGTTACATCATGAATAA

Domains

Predicted by InterProScan.

• UvrA interaction domain (UvrA_inter) (132-238)

• ABC transporter (ABC_tran) (624-860)

• UvrA DNA-binding domain (UvrA_DNA-bind) (288-396)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrA	Streptococcus pneumoniae R6	99.576	100	0.996
uvrA	Streptococcus pneumoniae TIGR4	99.576	100	0.996
uvrA	Streptococcus pneumoniae D39	99.576	100	0.996