Detailed information NTG0828808

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: SGQ79_RS13590
• Genome accession: NZ_CP138889
• Coordinates: 2686419..2688527 (+)
• Length: 702 a.a.
• NCBI ID: WP_217654602.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain 1221
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 2681419..2693527

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGQ79_RS13565 (SGQ79_13560)	-	2681490..2681708 (+)	219	WP_000011687.1	sterile alpha motif-like domain-containing protein	-
SGQ79_RS13570 (SGQ79_13565)	-	2682097..2682528 (+)	432	WP_000455858.1	CHAP domain-containing protein	-
SGQ79_RS13575 (SGQ79_13570)	-	2682667..2683944 (-)	1278	WP_001180327.1	hydroxymethylglutaryl-CoA reductase, degradative	-
SGQ79_RS13580 (SGQ79_13575)	-	2684198..2685364 (+)	1167	WP_000151986.1	hydroxymethylglutaryl-CoA synthase	-
SGQ79_RS13585 (SGQ79_13580)	-	2685535..2686056 (-)	522	WP_000262592.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
SGQ79_RS13590 (SGQ79_13585)	clpE	2686419..2688527 (+)	2109	WP_217654602.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
SGQ79_RS13595 (SGQ79_13590)	-	2688594..2688764 (-)	171	WP_000111116.1	FeoB-associated Cys-rich membrane protein	-
SGQ79_RS13600 (SGQ79_13595)	feoB	2688777..2690771 (-)	1995	WP_000432895.1	ferrous iron transport protein B	-
SGQ79_RS13605 (SGQ79_13600)	-	2690783..2691010 (-)	228	WP_000932073.1	ferrous iron transport protein A	-

Sequence

Protein

• Length: 702 a.a.
• Molecular weight: 78036.45 Da
• Isoelectric Point: 4.6408

>NTDB_id=828808 SGQ79_RS13590 WP_217654602.1 2686419..2688527(+) (clpE) [Staphylococcus aureus strain 1221]
MNNNFFNSDFDSILRRMMQDMQSSNQTSNKKYYINGKEVSPEELAQFTQQGGNHSAEQSAQAFQQAALRQQGQQGGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISI
DISSLEAGTQYRGAFEENIQKLVEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNILKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAIDKVATEKRISELEHDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDDNDIERLKNISNRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKDA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIIICTSNAGFGNGTDQEYDDIMHEMKKFFRPEFLNRFNGIVELLHLDKDALQDIVNLLLDDVQVTLDKKGITMNV
SQDAKDWLIEEGYDEDLGARPLRRIVEQQVRDKITDYYLDHTDVKHVDLDIEDNELVVKGKS

Nucleotide

• Length: 2109 bp

>NTDB_id=828808 SGQ79_RS13590 WP_217654602.1 2686419..2688527(+) (clpE) [Staphylococcus aureus strain 1221]
ATGAATAACAATTTTTTCAATAGTGACTTCGATTCTATTTTACGAAGAATGATGCAAGACATGCAAAGCTCAAATCAGAC
TAGTAACAAGAAATACTATATTAATGGTAAAGAAGTTTCACCGGAAGAATTAGCACAATTTACGCAACAGGGTGGTAATC
ATTCTGCCGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACTAAGACAACAAGGTCAACAAGGTGGCAATGGCAATTAT
TTAGAACAAATTGGTCGCAATCTTACGCAAGAGGCTCGTGACGGATTATTAGATCCAGTCATCGGTCGTGATAAAGAAAT
CCAAGAGACTGCAGAAGTCTTAAGTAGACGCACTAAAAACAATCCTATCCTAGTCGGAGAAGCTGGGGTTGGTAAAACTG
CGATTGTCGAAGGTTTAGCGCAAGCAATCGTTGAAGGGAACGTACCTGCAGCAATCAAAGATAAAGAAATTATATCTATA
GATATTTCATCGCTTGAAGCTGGAACGCAATATCGTGGCGCCTTTGAAGAAAACATCCAAAAGTTAGTTGAAGGCGTTAA
ATCATCACAAAATGCTGTGCTCTTCTTTGACGAAATTCACCAAATCATCGGTTCCGGTGCAACTGGAAGTGATTCCGGTA
GTAAAGGGTTATCTGATATTTTAAAACCAGCATTAAGTCGTGGTGAAATTTCAATTATAGGTGCAACGACTCAAGATGAA
TATCGAAACAATATTCTTAAAGATGCTGCATTAACGCGCAGATTTAATGAAGTACTTGTTAATGAACCAAGTGCTAAAGA
TACTGTTGAAATTTTAAAAGGTATTCGCGAAAAATTCGAAGAACACCATCAAGTAAAATTACCAGATGACGTATTAAAAG
CATGTGTTGACTTATCAATTCAATATATTCCACAACGATTATTACCAGATAAAGCAATCGATGTGTTAGATATTACAGCA
GCACATTTATCTGCACAAAGCCCTGCTATTGATAAAGTCGCGACTGAAAAACGTATTTCTGAATTGGAACATGATAAGCG
TAAAGCGGTAAGTGCTGAAGAATATAAAAAAGCTGACGACATTCAAAATGAAATCAAATCATTACAAGATAAATTAGAAA
ATAGTAATGGTGAACATACTGCCGTTGCTACTGTTCATGATATTTCAGATACTATTCAACGATTAACTGGTATTCCAGTT
TCTCAAATGGATGATAACGATATTGAACGTTTAAAAAATATTTCTAATCGTTTAAGAAGTAAAATCATAGGTCAAGATCA
AGCTGTAGAAATGGTTTCTCGTGCAATTCGCCGTAATCGTGCTGGGTTTGATGACGGCAACCGTCCAATTGGCAGTTTCC
TATTTGTTGGCCCTACTGGTGTTGGTAAAACAGAGCTTGCTAAACAATTAGCAATTGATCTATTTGGTAATAAAGATGCA
CTGATTCGACTTGATATGAGTGAATATAGTGACACAACAGCTGTTTCAAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGATGACAATTCAAATACGTTAACTGAAAAAGTACGCCGTAATCCATATTCAGTCATTCTATTTGATGAAATCGAAA
AAGCAAATCCACAAATTTTAACATTGTTATTACAAGTAATGGATGATGGTAATTTGACTGATGGTCAAGGTAATGTCATC
AACTTTAAAAATACAATTATTATTTGTACATCAAATGCTGGCTTTGGTAACGGTACAGACCAAGAATACGATGACATTAT
GCATGAAATGAAAAAATTCTTCCGCCCTGAATTCCTTAACCGCTTCAACGGTATCGTTGAACTCTTACATTTAGATAAAG
ATGCATTACAAGATATCGTCAACTTATTATTAGACGATGTCCAAGTAACATTAGATAAAAAAGGTATTACGATGAATGTC
TCTCAAGATGCAAAAGATTGGTTAATTGAAGAAGGTTATGATGAAGACTTAGGCGCACGCCCATTAAGACGTATTGTTGA
ACAGCAAGTACGTGACAAAATTACAGATTACTATTTAGATCATACTGACGTTAAACATGTGGATTTAGATATCGAGGACA
ATGAATTAGTCGTCAAAGGTAAATCATGA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

• AAA domain (Cdc48 subfamily) (AAA_2) (448-603)

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

• AAA lid domain (AAA_lid_9) (264-363)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	48.056	91.595	0.44
clpE	Streptococcus pneumoniae Rx1	47.65	87.892	0.419
clpE	Streptococcus pneumoniae D39	47.65	87.892	0.419
clpE	Streptococcus pneumoniae R6	47.65	87.892	0.419
clpE	Streptococcus pneumoniae TIGR4	47.65	87.892	0.419
clpC	Lactococcus lactis subsp. cremoris KW2	45.886	90.028	0.413
clpC	Bacillus subtilis subsp. subtilis str. 168	43.798	93.02	0.407
clpC	Streptococcus thermophilus LMD-9	44.32	89.031	0.395
clpC	Streptococcus thermophilus LMG 18311	44.16	89.031	0.393
clpC	Streptococcus pneumoniae TIGR4	43.78	88.177	0.386
clpC	Streptococcus pneumoniae Rx1	43.78	88.177	0.386
clpC	Streptococcus pneumoniae D39	43.78	88.177	0.386
clpC	Streptococcus mutans UA159	43.415	87.607	0.38
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.215	88.746	0.375