Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   SGQ79_RS08365 Genome accession   NZ_CP138889
Coordinates   1731678..1732940 (-) Length   420 a.a.
NCBI ID   WP_000472293.1    Uniprot ID   Q6GG31
Organism   Staphylococcus aureus strain 1221     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1726678..1737940
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGQ79_RS08340 (SGQ79_08335) - 1726876..1727544 (-) 669 WP_000805956.1 uroporphyrinogen-III synthase -
  SGQ79_RS08345 (SGQ79_08340) hemC 1727566..1728492 (-) 927 WP_001230226.1 hydroxymethylbilane synthase -
  SGQ79_RS08350 (SGQ79_08345) - 1728534..1729349 (-) 816 WP_001157329.1 cytochrome c biogenesis protein -
  SGQ79_RS08355 (SGQ79_08350) hemA 1729371..1730717 (-) 1347 WP_000545453.1 glutamyl-tRNA reductase -
  SGQ79_RS08360 (SGQ79_08355) yihA 1730934..1731524 (-) 591 WP_000867695.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  SGQ79_RS08365 (SGQ79_08360) clpX 1731678..1732940 (-) 1263 WP_000472293.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  SGQ79_RS08370 (SGQ79_08365) tig 1733091..1734392 (-) 1302 WP_000127572.1 trigger factor -
  SGQ79_RS08375 (SGQ79_08370) - 1734440..1734550 (-) 111 WP_001790560.1 hypothetical protein -
  SGQ79_RS08380 (SGQ79_08375) - 1734555..1735484 (-) 930 WP_001280010.1 hypothetical protein -
  SGQ79_RS08385 (SGQ79_08380) - 1735503..1736111 (-) 609 WP_000032657.1 NUDIX domain-containing protein -
  SGQ79_RS08390 (SGQ79_08385) rplT 1736253..1736609 (-) 357 WP_001138360.1 50S ribosomal protein L20 -
  SGQ79_RS08395 (SGQ79_08390) rpmI 1736656..1736856 (-) 201 WP_001125540.1 50S ribosomal protein L35 -
  SGQ79_RS08400 (SGQ79_08395) infC 1736885..1737412 (-) 528 WP_001791162.1 translation initiation factor IF-3 -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 46279.44 Da        Isoelectric Point: 4.2645

>NTDB_id=828786 SGQ79_RS08365 WP_000472293.1 1731678..1732940(-) (clpX) [Staphylococcus aureus strain 1221]
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAITELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=828786 SGQ79_RS08365 WP_000472293.1 1731678..1732940(-) (clpX) [Staphylococcus aureus strain 1221]
ATGTTTAAATTCAATGAAGATGAAGAAAATTTGAAATGCTCTTTCTGCGGAAAAGACCAAGATCAAGTAAAAAAACTTGT
AGCAGGAAGTGGTGTATATATTTGTAATGAGTGTATTGAATTATGCTCAGAAATCGTCGAAGAAGAATTAGCTCAAAATA
CTTCTGAAGCGATTACAGAATTACCTACTCCTAAAGAAATTATGGATCATTTAAACGAATATGTTATTGGTCAAGAAAAA
GCTAAAAAATCTTTAGCTGTGGCTGTTTATAACCACTATAAGCGTATTCAACAATTAGGACCAAAAGAAGATGATGTTGA
GTTACAAAAAAGTAACATTGCCTTAATTGGGCCAACAGGTAGTGGTAAAACATTATTAGCTCAAACCTTAGCCAAGACGT
TGAATGTACCATTTGCAATTGCAGATGCGACAAGTTTAACTGAAGCTGGCTATGTAGGCGATGATGTTGAAAATATCTTG
TTGAGATTAATTCAAGCAGCTGACTTTGACATTGATAAAGCCGAAAAAGGTATTATTTATGTAGATGAAATTGATAAAAT
TGCACGTAAATCTGAAAACACATCTATAACACGTGACGTTTCAGGTGAAGGTGTTCAACAAGCATTGCTTAAAATCTTAG
AAGGCACAACTGCGAGTGTTCCGCCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCAAATTGATACAACAAAT
ATCTTATTTATTCTTGGTGGTGCCTTTGATGGTATTGAAGAAGTGATTAAGCGCCGTCTTGGTGAAAAAGTTATTGGTTT
CTCAAGCAATGAAGCTGATAAATATGACGAACAAGCATTATTAGCACAAATTCGCCCAGAAGATTTGCAAGCCTATGGTT
TGATTCCTGAATTTATCGGACGTGTGCCAATTGTAGCTAATTTAGAAACATTAGATGTAACTGCGTTGAAAAACATCTTA
ACGCAACCTAAAAATGCACTTGTGAAACAATATACTAAAATGCTGGAATTAGATGATGTGGATTTAGAGTTCACTGAAGA
AGCTTTATCAGCAATTAGTGAAAAAGCAATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCAATCATAGAAGAATCGT
TAATCGATATTATGTTTGATGTGCCTTCTAACGAAAATGTAACGAAGGTAGTTATTACAGCACAAACAATTAATGAAGAA
ACTGAACCAGAACTATACGACGCAGAAGGTAATTTAATTAATAATAGTAAAACATCAGCTTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q6GG31

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

66.917

95

0.636
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.456

94.048

0.531