Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   QL049_RS08095 Genome accession   NZ_CP124856
Coordinates   1724538..1725254 (+) Length   238 a.a.
NCBI ID   WP_014613411.1    Uniprot ID   X2JA42
Organism   Staphylococcus pseudintermedius strain 452964 isolate human     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1719538..1730254
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QL049_RS08075 (QL049_08080) - 1720944..1721747 (+) 804 WP_014613416.1 carbon-nitrogen family hydrolase -
  QL049_RS12230 - 1722031..1722111 (-) 81 WP_110161296.1 delta-lysin family phenol-soluble modulin -
  QL049_RS08080 (QL049_08085) - 1722503..1723069 (+) 567 WP_130921879.1 accessory gene regulator AgrB -
  QL049_RS08085 (QL049_08090) agrD 1723071..1723208 (+) 138 WP_019166405.1 cyclic lactone autoinducer peptide AgrD -
  QL049_RS08090 (QL049_08095) agrC 1723232..1724524 (+) 1293 WP_096636795.1 quorum-sensing sensor histidine kinase AgrC -
  QL049_RS08095 (QL049_08100) agrA 1724538..1725254 (+) 717 WP_014613411.1 quorum-sensing response regulator AgrA Regulator
  QL049_RS08100 (QL049_08105) - 1725314..1726258 (-) 945 WP_063278587.1 carbohydrate kinase -
  QL049_RS08105 (QL049_08110) - 1726262..1727746 (-) 1485 WP_063278588.1 sucrose-6-phosphate hydrolase -
  QL049_RS08110 (QL049_08115) - 1727802..1728749 (-) 948 WP_199274911.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 28002.15 Da        Isoelectric Point: 5.4331

>NTDB_id=828532 QL049_RS08095 WP_014613411.1 1724538..1725254(+) (agrA) [Staphylococcus pseudintermedius strain 452964 isolate human]
MKILICEDDPKQRERMVSIIENYIMIEEKPMKIELATNDPYAILETSKNMTDIGCYFLDIQLESDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPEELRTRIIDCLETALKRLDLLTKDHTVETLELKRGTSSVYVNYDDVM
FFESSPKSHRLIAHLDNRQIEFYGNLKELAQLDDRFFRCHNSYVLNRRNITSVDTKERIAYFKNEEFCYVSVRNLKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=828532 QL049_RS08095 WP_014613411.1 1724538..1725254(+) (agrA) [Staphylococcus pseudintermedius strain 452964 isolate human]
ATGAAAATTTTGATTTGTGAGGATGATCCTAAACAACGCGAACGTATGGTGTCCATTATTGAAAACTATATTATGATTGA
AGAGAAGCCGATGAAAATTGAGCTTGCTACCAATGACCCTTATGCTATCTTAGAAACTTCTAAAAACATGACTGATATTG
GCTGCTACTTTTTAGATATTCAATTAGAGTCTGATATTAACGGGATTAAATTAGGGAGCGAAATTCGTAAGCACGATCCT
GTTGGGAATATTATTTTTGTGACGAGTCATAGTGAGCTGACGTACTTGACTTTTGTCTATAAAGTGGCTGCCATGGATTT
TATTTTTAAAGATGATCCTGAAGAATTAAGGACACGCATTATCGATTGTTTAGAAACAGCATTAAAACGGCTTGATTTAT
TAACAAAAGATCATACTGTTGAAACTTTGGAACTCAAACGCGGAACAAGCTCGGTTTACGTGAACTATGACGACGTGATG
TTTTTCGAGTCTTCACCGAAGTCACATCGTTTAATCGCGCATTTAGACAATCGTCAAATCGAATTTTACGGCAATTTGAA
AGAGTTAGCTCAACTCGATGATCGATTCTTCAGATGCCACAACAGTTATGTGCTAAACAGAAGAAATATTACAAGTGTCG
ATACGAAAGAACGGATTGCTTATTTCAAAAATGAAGAATTTTGTTACGTGTCGGTGCGTAATTTGAAGAAAATTTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(152-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB X2JA42

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

83.193

100

0.832