Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   QLF90_RS11420 Genome accession   NZ_CP124854
Coordinates   2237937..2238653 (+) Length   238 a.a.
NCBI ID   WP_410530097.1    Uniprot ID   -
Organism   Staphylococcus aureus strain ED86     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2232937..2243653
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QLF90_RS11390 (QLF90_11385) - 2233149..2233775 (+) 627 WP_000522388.1 nitroreductase family protein -
  QLF90_RS11395 (QLF90_11390) - 2234136..2234921 (+) 786 WP_000867948.1 carbon-nitrogen family hydrolase -
  QLF90_RS11400 hld 2235524..2235604 (-) 81 WP_000046022.1 delta-hemolysin -
  QLF90_RS11405 (QLF90_11400) - 2235894..2236457 (+) 564 WP_001105709.1 accessory gene regulator AgrB -
  QLF90_RS11410 (QLF90_11405) agrD 2236461..2236601 (+) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  QLF90_RS11415 (QLF90_11410) agrC 2236626..2237918 (+) 1293 WP_000387814.1 quorum-sensing sensor histidine kinase AgrC -
  QLF90_RS11420 (QLF90_11415) agrA 2237937..2238653 (+) 717 WP_410530097.1 quorum-sensing response regulator AgrA Regulator
  QLF90_RS11425 (QLF90_11420) - 2239027..2239986 (-) 960 WP_001253292.1 carbohydrate kinase family protein -
  QLF90_RS11430 (QLF90_11425) - 2239983..2241467 (-) 1485 WP_001791588.1 sucrose-6-phosphate hydrolase -
  QLF90_RS11435 (QLF90_11430) - 2241616..2242566 (-) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27919.93 Da        Isoelectric Point: 6.0927

>NTDB_id=828486 QLF90_RS11420 WP_410530097.1 2237937..2238653(+) (agrA) [Staphylococcus aureus strain ED86]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFIYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=828486 QLF90_RS11420 WP_410530097.1 2237937..2238653(+) (agrA) [Staphylococcus aureus strain ED86]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATCAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTATCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGTCATAATATCGAATCTATTG
ATTCGAAAGAGCGTATTGTTTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996