Detailed information NTG0828447

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: QJ053_RS13570
• Genome accession: NZ_CP124853
• Coordinates: 2697001..2697888 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain ED83
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2692001..2702888

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QJ053_RS13540 (QJ053_13540)	-	2692019..2692111 (+)	93	WP_031774855.1	hypothetical protein	-
QJ053_RS13545 (QJ053_13545)	-	2692219..2692716 (-)	498	WP_001065267.1	glutathione peroxidase	-
QJ053_RS13550 (QJ053_13550)	-	2692726..2692986 (-)	261	WP_001791293.1	hypothetical protein	-
QJ053_RS13555 (QJ053_13555)	-	2693368..2693481 (-)	114	WP_410530372.1	hypothetical protein	-
QJ053_RS13560 (QJ053_13560)	-	2694141..2696141 (-)	2001	WP_410530373.1	FtsX-like permease family protein	-
QJ053_RS13565 (QJ053_13565)	-	2696138..2696893 (-)	756	WP_000923764.1	ABC transporter ATP-binding protein	-
QJ053_RS13570 (QJ053_13570)	braS	2697001..2697888 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
QJ053_RS13575 (QJ053_13575)	braR	2697899..2698564 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
QJ053_RS13580 (QJ053_13580)	-	2698590..2698790 (-)	201	WP_000604727.1	hypothetical protein	-
QJ053_RS13585 (QJ053_13585)	-	2698988..2700412 (+)	1425	WP_410530116.1	alkaline phosphatase	-
QJ053_RS13590	-	2700472..2700573 (-)	102	WP_000731972.1	SE2200 family small protein	-
QJ053_RS13595 (QJ053_13595)	-	2700695..2701150 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
QJ053_RS13600 (QJ053_13600)	-	2701395..2702156 (-)	762	WP_000323448.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=828447 QJ053_RS13570 WP_000143420.1 2697001..2697888(-) (braS) [Staphylococcus aureus strain ED83]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=828447 QJ053_RS13570 WP_000143420.1 2697001..2697888(-) (braS) [Staphylococcus aureus strain ED83]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAATTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993