Detailed information NTG0828441

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QJ053_RS09670
• Genome accession: NZ_CP124853
• Coordinates: 1953531..1954574 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain ED83
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1948531..1959574

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QJ053_RS09640 (QJ053_09635)	-	1949028..1950142 (-)	1115	Protein_1859	aminopeptidase	-
QJ053_RS09645 (QJ053_09645)	-	1950211..1950411 (-)	201	WP_000180460.1	DUF1128 family protein	-
QJ053_RS09650 (QJ053_09650)	-	1950558..1951022 (+)	465	WP_000228670.1	low molecular weight protein-tyrosine-phosphatase	-
QJ053_RS09655 (QJ053_09655)	-	1951029..1951304 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
QJ053_RS09660 (QJ053_09660)	-	1951582..1952799 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
QJ053_RS09665 (QJ053_09665)	vraR	1952912..1953541 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
QJ053_RS09670 (QJ053_09670)	vraS	1953531..1954574 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
QJ053_RS09675 (QJ053_09675)	liaF	1954571..1955272 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
QJ053_RS09680 (QJ053_09680)	-	1955287..1955673 (-)	387	WP_173950187.1	hypothetical protein	-
QJ053_RS09685 (QJ053_09685)	map	1955890..1956648 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
QJ053_RS09690 (QJ053_09690)	-	1957230..1958216 (+)	987	WP_001014423.1	FUSC family protein	-
QJ053_RS09695 (QJ053_09695)	-	1958706..1959119 (-)	414	WP_001549145.1	hypothetical protein	-
QJ053_RS09700 (QJ053_09700)	-	1959148..1959258 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=828441 QJ053_RS09670 WP_001017131.1 1953531..1954574(-) (vraS) [Staphylococcus aureus strain ED83]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=828441 QJ053_RS09670 WP_001017131.1 1953531..1954574(-) (vraS) [Staphylococcus aureus strain ED83]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGACTT
ATACCATACACTTGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCGCCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1