Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   SGQ71_RS10080 Genome accession   NZ_CP138875
Coordinates   2028932..2029645 (+) Length   237 a.a.
NCBI ID   WP_001031454.1    Uniprot ID   A0A0H2XG68
Organism   Staphylococcus aureus strain 11     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2023932..2034645
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGQ71_RS10015 (SGQ71_10010) - 2024357..2025130 (-) 774 WP_001288247.1 AAA family ATPase -
  SGQ71_RS10020 (SGQ71_10015) - 2025130..2025609 (-) 480 WP_086037491.1 siphovirus Gp157 family protein -
  SGQ71_RS10025 (SGQ71_10020) - 2025602..2025838 (-) 237 WP_154440298.1 hypothetical protein -
  SGQ71_RS10030 (SGQ71_10025) - 2025847..2026107 (-) 261 WP_000291090.1 DUF1108 family protein -
  SGQ71_RS10035 (SGQ71_10030) - 2026199..2026360 (-) 162 WP_052995610.1 DUF1270 family protein -
  SGQ71_RS10040 (SGQ71_10035) - 2026357..2026677 (-) 321 WP_001120936.1 DUF771 domain-containing protein -
  SGQ71_RS10045 (SGQ71_10040) - 2026731..2026886 (+) 156 Protein_1940 hypothetical protein -
  SGQ71_RS10050 (SGQ71_10045) - 2026910..2027170 (-) 261 WP_000435343.1 hypothetical protein -
  SGQ71_RS10055 (SGQ71_10050) - 2027183..2027935 (-) 753 WP_103246153.1 phage antirepressor KilAC domain-containing protein -
  SGQ71_RS10060 (SGQ71_10055) - 2027986..2028315 (+) 330 WP_000128907.1 hypothetical protein -
  SGQ71_RS10065 (SGQ71_10060) - 2028304..2028519 (-) 216 WP_001025404.1 MW1434 family type I TA system toxin -
  SGQ71_RS10070 (SGQ71_10065) - 2028535..2028798 (-) 264 WP_000854072.1 helix-turn-helix transcriptional regulator -
  SGQ71_RS10075 (SGQ71_10070) - 2028795..2028969 (-) 175 Protein_1946 transcriptional regulator -
  SGQ71_RS10080 (SGQ71_10075) irvR 2028932..2029645 (+) 714 WP_001031454.1 XRE family transcriptional regulator Regulator
  SGQ71_RS10085 (SGQ71_10080) - 2029661..2030593 (+) 933 WP_353059097.1 exonuclease domain-containing protein -
  SGQ71_RS10090 (SGQ71_10085) - 2030599..2030940 (+) 342 WP_000591749.1 hypothetical protein -
  SGQ71_RS10095 (SGQ71_10090) - 2031144..2031326 (+) 183 WP_000705240.1 hypothetical protein -
  SGQ71_RS10100 (SGQ71_10095) - 2031404..2032117 (+) 714 WP_001582614.1 type II toxin-antitoxin system PemK/MazF family toxin -
  SGQ71_RS10105 (SGQ71_10100) - 2032308..2033345 (+) 1038 WP_000857198.1 site-specific integrase -
  SGQ71_RS10110 (SGQ71_10105) sph 2033396..2034226 (+) 831 Protein_1953 sphingomyelin phosphodiesterase -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27017.58 Da        Isoelectric Point: 5.0545

>NTDB_id=828272 SGQ71_RS10080 WP_001031454.1 2028932..2029645(+) (irvR) [Staphylococcus aureus strain 11]
MNKERNIIIAKNIRKFLNDSNMSQKKLAELINIKPSTLSDYLNLRSNPSHGVIQRIADVFEVGKSDIDTTYKDDNDITSI
YNKLTPPRQENVLNYANEQLEEQNSKGDNVVDINSYKQEKTPVNVNGCVSAGVGERLHDETLFTEMVKGPIPTHDLALKV
NGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKDYDDLHFYRNESVRLIGKVIL

Nucleotide


Download         Length: 714 bp        

>NTDB_id=828272 SGQ71_RS10080 WP_001031454.1 2028932..2029645(+) (irvR) [Staphylococcus aureus strain 11]
ATGAACAAAGAAAGAAATATTATTATAGCCAAAAACATTAGAAAATTTCTCAACGATTCAAATATGTCTCAAAAGAAACT
TGCTGAACTCATTAACATAAAACCATCTACTTTAAGCGATTATTTAAATTTACGTTCCAACCCCTCTCACGGCGTTATAC
AAAGGATAGCTGATGTTTTCGAGGTTGGTAAAAGCGACATAGATACTACATACAAAGACGATAACGACATCACTTCCATA
TACAACAAACTCACACCTCCCCGCCAAGAAAACGTACTTAACTATGCAAATGAACAATTGGAAGAACAGAATTCTAAAGG
AGATAACGTTGTAGATATTAATTCATATAAACAGGAGAAAACTCCAGTTAACGTCAATGGTTGCGTCTCTGCTGGTGTAG
GAGAACGTTTACACGATGAAACGCTATTTACTGAAATGGTTAAAGGACCTATCCCCACACACGATTTAGCGTTAAAAGTA
AATGGTGATTCTATGGAACCTATGTTTAAAGATGGCGAAATCATATTTGTGGAGAAAACTCACAATATAAAGAATGGACA
AATTGGTATATTCATCATTGAAGAAGAAGCGTACGTTAAGAAAGTCTTTGTTGAAGATGATAGATTGACTCTAGTTTCAC
TAAATAAAGATTACGACGATCTACACTTTTATAGAAATGAAAGTGTGAGGTTAATTGGAAAAGTTATTTTATAA

Domains

Predicted by InterProScan.

Peptidase S24-like (Peptidase_S24)

(127-236)

Helix-turn-helix (HTH_3)

(13-63)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2XG68

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

33.929

100

0.401