Detailed information    

insolico Bioinformatically predicted

Overview

Name   comS   Type   Regulator
Locus tag   H7675_RS09505 Genome accession   NZ_AP023389
Coordinates   53882..53977 (+) Length   31 a.a.
NCBI ID   WP_198462994.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain KUN-0012590     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 48882..58977
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7675_RS00315 (KUN2590_00280) purK 48953..50026 (+) 1074 WP_023611330.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  H7675_RS00320 (KUN2590_00290) - 50028..51446 (+) 1419 WP_023612101.1 hypothetical protein -
  H7675_RS00325 (KUN2590_00300) purB 51466..52758 (+) 1293 WP_023612104.1 adenylosuccinate lyase -
  H7675_RS00330 (KUN2590_00310) rgg4 52888..53798 (+) 911 Protein_32 transcriptional regulator Rgg4/ComR -
  H7675_RS09505 comS 53882..53977 (+) 96 WP_198462994.1 quorum-sensing system DWW-type pheromone Regulator
  H7675_RS00335 (KUN2590_00330) ruvB 54024..55022 (+) 999 WP_002986679.1 Holliday junction branch migration DNA helicase RuvB -
  H7675_RS00340 (KUN2590_00340) - 55160..55598 (+) 439 Protein_35 low molecular weight protein-tyrosine-phosphatase -
  H7675_RS00345 (KUN2590_00350) - 55622..56023 (+) 402 WP_002986671.1 MORN repeat-containing protein -
  H7675_RS00350 (KUN2590_00360) - 56020..57795 (+) 1776 WP_014407199.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 31 a.a.        Molecular weight: 3857.66 Da        Isoelectric Point: 10.0436

>NTDB_id=82814 H7675_RS09505 WP_198462994.1 53882..53977(+) (comS) [Streptococcus pyogenes strain KUN-0012590]
MLKKYKYYFIFAALLSFKVVQELSAVDWWRL

Nucleotide


Download         Length: 96 bp        

>NTDB_id=82814 H7675_RS09505 WP_198462994.1 53882..53977(+) (comS) [Streptococcus pyogenes strain KUN-0012590]
ATGTTAAAAAAGTATAAGTACTATTTTATATTCGCAGCTCTACTATCTTTTAAAGTAGTTCAAGAGCTTAGTGCTGTTGA
CTGGTGGCGATTATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus pyogenes MGAS8232

100

100

1
  comS Streptococcus pyogenes MGAS315

45.161

100

0.452

Multiple sequence alignment