Detailed information
Bioinformatically predicted
Overview
| Name | radA | Type | Machinery gene |
| Locus tag | H7675_RS01150 | Genome accession | NZ_AP023389 |
| Coordinates | 209471..210832 (+) | Length | 453 a.a. |
| NCBI ID | WP_002986109.1 | Uniprot ID | A0A4Q1R665 |
| Organism | Streptococcus pyogenes strain KUN-0012590 | ||
| Function | homologous recombination (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 183606..229424 | 209471..210832 | within | 0 |
Gene organization within MGE regions
Location: 183606..229424
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H7675_RS01040 | - | 184834..186144 (-) | 1311 | WP_031488784.1 | SLC13 family permease | - |
| H7675_RS01045 (KUN2590_01630) | nadC | 186368..187240 (+) | 873 | WP_002992869.1 | carboxylating nicotinate-nucleotide diphosphorylase | - |
| H7675_RS01055 (KUN2590_01660) | - | 188968..189831 (-) | 864 | WP_031488685.1 | DUF975 family protein | - |
| H7675_RS09445 | - | 189868..190053 (+) | 186 | WP_002986321.1 | hypothetical protein | - |
| H7675_RS01060 (KUN2590_01670) | tgt | 190050..191192 (+) | 1143 | WP_031488684.1 | tRNA guanosine(34) transglycosylase Tgt | - |
| H7675_RS01065 | - | 191410..191721 (+) | 312 | WP_002987947.1 | CHY zinc finger protein | - |
| H7675_RS01070 (KUN2590_01680) | - | 191725..192264 (+) | 540 | WP_002986314.1 | biotin transporter BioY | - |
| H7675_RS01075 (KUN2590_01690) | - | 192404..193183 (+) | 780 | WP_011528209.1 | MBL fold metallo-hydrolase | - |
| H7675_RS01080 (KUN2590_01700) | tadA | 193183..193698 (+) | 516 | WP_184004793.1 | tRNA adenosine(34) deaminase TadA | - |
| H7675_RS01085 (KUN2590_01710) | - | 194312..195544 (-) | 1233 | WP_031488683.1 | transglutaminase domain-containing protein | - |
| H7675_RS01095 (KUN2590_01720) | speG | 195944..196648 (+) | 705 | WP_031488682.1 | streptococcal pyrogenic exotoxin SpeG | - |
| H7675_RS01100 (KUN2590_01740) | - | 197104..198453 (+) | 1350 | WP_014635263.1 | glucose-6-phosphate isomerase | - |
| H7675_RS01105 (KUN2590_01750) | - | 198802..200310 (-) | 1509 | WP_002986134.1 | helix-turn-helix domain-containing protein | - |
| H7675_RS01110 (KUN2590_01760) | - | 200998..201669 (+) | 672 | WP_031488681.1 | rhomboid family intramembrane serine protease | - |
| H7675_RS01115 (KUN2590_01770) | galU | 201768..202667 (-) | 900 | WP_002986125.1 | UTP--glucose-1-phosphate uridylyltransferase GalU | - |
| H7675_RS01120 (KUN2590_01780) | - | 202700..203716 (-) | 1017 | WP_002986123.1 | NAD(P)H-dependent glycerol-3-phosphate dehydrogenase | - |
| H7675_RS01125 (KUN2590_01790) | - | 204014..204463 (+) | 450 | WP_002986120.1 | MarR family winged helix-turn-helix transcriptional regulator | - |
| H7675_RS01130 (KUN2590_01800) | - | 204456..206162 (+) | 1707 | WP_031488680.1 | ABC transporter ATP-binding protein | - |
| H7675_RS01135 (KUN2590_01810) | - | 206165..207949 (+) | 1785 | WP_023610145.1 | ABC transporter ATP-binding protein | - |
| H7675_RS01140 (KUN2590_01820) | - | 208067..208834 (+) | 768 | WP_011054158.1 | epoxyqueuosine reductase QueH | - |
| H7675_RS01145 (KUN2590_01830) | - | 208944..209390 (+) | 447 | WP_002986111.1 | dUTP diphosphatase | - |
| H7675_RS01150 (KUN2590_01840) | radA | 209471..210832 (+) | 1362 | WP_002986109.1 | DNA repair protein RadA | Machinery gene |
| H7675_RS01155 (KUN2590_01850) | - | 211021..211518 (+) | 498 | WP_010921867.1 | beta-class carbonic anhydrase | - |
| H7675_RS01160 (KUN2590_01860) | - | 211899..212213 (+) | 315 | WP_000420682.1 | YdcP family protein | - |
| H7675_RS01165 (KUN2590_01870) | - | 212229..212615 (+) | 387 | WP_000985015.1 | YdcP family protein | - |
| H7675_RS01170 (KUN2590_01880) | - | 212644..214029 (+) | 1386 | WP_000813488.1 | FtsK/SpoIIIE domain-containing protein | - |
| H7675_RS01175 | - | 214032..214184 (+) | 153 | WP_000879507.1 | hypothetical protein | - |
| H7675_RS01180 (KUN2590_01890) | mobT | 214207..215412 (+) | 1206 | WP_000398284.1 | MobT family relaxase | - |
| H7675_RS01185 (KUN2590_01900) | - | 215455..215676 (+) | 222 | WP_001009056.1 | hypothetical protein | - |
| H7675_RS01190 (KUN2590_01910) | - | 215793..216290 (+) | 498 | WP_000342539.1 | antirestriction protein ArdA | - |
| H7675_RS01195 (KUN2590_01920) | - | 216379..216771 (+) | 393 | WP_000723888.1 | conjugal transfer protein | - |
| H7675_RS01200 (KUN2590_01930) | - | 216755..219202 (+) | 2448 | WP_000331160.1 | ATP-binding protein | - |
| H7675_RS01205 (KUN2590_01950) | - | 219205..221382 (+) | 2178 | Protein_191 | CD3337/EF1877 family mobilome membrane protein | - |
| H7675_RS01210 (KUN2590_01960) | - | 221379..222380 (+) | 1002 | WP_000769868.1 | lysozyme family protein | - |
| H7675_RS01215 (KUN2590_01970) | - | 222377..223312 (+) | 936 | WP_001224320.1 | conjugal transfer protein | - |
| H7675_RS09510 | - | 223626..223673 (+) | 48 | Protein_194 | hypothetical protein | - |
| H7675_RS01225 (KUN2590_01980) | tet(M) | 223689..225608 (+) | 1920 | WP_002414694.1 | tetracycline resistance ribosomal protection protein Tet(M) | - |
| H7675_RS01230 | - | 225727..225894 (+) | 168 | WP_000336323.1 | cysteine-rich KTR domain-containing protein | - |
| H7675_RS01235 (KUN2590_01990) | - | 225954..226307 (-) | 354 | WP_001227347.1 | helix-turn-helix transcriptional regulator | - |
| H7675_RS01240 (KUN2590_02000) | - | 226812..227234 (+) | 423 | WP_000804885.1 | sigma-70 family RNA polymerase sigma factor | - |
| H7675_RS01245 (KUN2590_02010) | - | 227231..227461 (+) | 231 | WP_000857133.1 | helix-turn-helix domain-containing protein | - |
| H7675_RS09260 | - | 227687..227938 (-) | 252 | WP_001845478.1 | hypothetical protein | - |
| H7675_RS01250 (KUN2590_02020) | - | 227922..228125 (+) | 204 | WP_000814511.1 | excisionase | - |
| H7675_RS01255 (KUN2590_02030) | - | 228207..229424 (+) | 1218 | WP_001291561.1 | tyrosine-type recombinase/integrase | - |
Sequence
Protein
Download Length: 453 a.a. Molecular weight: 49386.68 Da Isoelectric Point: 6.0962
>NTDB_id=82770 H7675_RS01150 WP_002986109.1 209471..210832(+) (radA) [Streptococcus pyogenes strain KUN-0012590]
MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKNARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRV
LGGGVVPGSLILIGGDPGIGKSTLLLQVSTQLANKGTVLYVSGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNAR
RTTTGLDFNRVSLIMAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGEIGLTGEIR
RVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKAVFS
MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKNARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRV
LGGGVVPGSLILIGGDPGIGKSTLLLQVSTQLANKGTVLYVSGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNAR
RTTTGLDFNRVSLIMAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGEIGLTGEIR
RVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKAVFS
Nucleotide
Download Length: 1362 bp
>NTDB_id=82770 H7675_RS01150 WP_002986109.1 209471..210832(+) (radA) [Streptococcus pyogenes strain KUN-0012590]
ATGGCAAAGAAAAAAGCAACCTTTATCTGTCAGGAGTGTGGCTACCAGTCGCCAAAGTATTTAGGGCGCTGTCCAAATTG
CTCGGCCTGGTCTTCTTTTGTGGAAGAAGTAGAGGTCAAAGAAGTCAAAAATGCCCGTGTTAGTCTAGCTGGAGAAAAGT
CCAGACCGGTTAAACTAAAAGATGTGGATAATATTAGTTATCACAGAACACAGACTGACATGTCTGAATTTAATAGAGTT
CTTGGAGGGGGTGTGGTTCCTGGAAGCTTGATTTTAATTGGTGGTGATCCAGGTATTGGAAAATCCACCTTACTCTTGCA
GGTATCCACGCAGCTCGCTAATAAGGGAACGGTTCTCTATGTGTCTGGGGAAGAATCAGCAGAGCAGATTAAACTGCGGA
GTGAGCGTCTGGGTGATATTGACAATGAATTTTACCTCTATGCCGAAACCAATATGCAAGCTATTCGCACAGAAATTGAA
AATATTAAACCAGATTTTTTAATTATTGACTCCATTCAGACTATCATGAGCCCTGATATTACAGGTGTTCAAGGATCAGT
CAGTCAGGTGAGAGAAGTCACTGCAGAATTGATGCAGCTTGCAAAGACGAACAACATTGCAACCTTTATTGTGGGTCATG
TCACCAAGGAAGGAACCTTGGCTGGGCCTCGTATGTTAGAACATATGGTGGATACCGTTCTCTACTTTGAAGGGGAAAGG
CATCACACCTTTCGCATTCTGCGGGCTGTGAAAAACCGCTTTGGCTCCACTAATGAGATTGGCATCTTTGAAATGCAGTC
TGGCGGTTTGGTAGAGGTCTTAAATCCTAGTCAAGTCTTTTTAGAGGAACGCTTAGATGGGGCAACAGGATCGGCTGTCG
TTGTAACGATGGAAGGAAGTCGTCCTATTTTAGCAGAGGTGCAATCTTTAGTGACACCAACCGTTTTTGGCAATGCCAGA
CGAACCACTACGGGACTTGATTTCAATCGCGTAAGCCTAATAATGGCAGTTTTAGAAAAGCGCTGTGGTTTACTCTTACA
AAATCAAGATGCCTACCTCAAGTCGGCTGGTGGTGTCAAACTAGACGAACCTGCCATTGATTTGGCAGTCGCTGTGGCTA
TCGCATCCAGTTATAAGGAAAAACCAACCAGCCCTCAAGAAGCTTTCTTAGGCGAGATCGGGTTAACAGGTGAGATTCGG
CGAGTGACCCGTATTGAGCAACGGATTAATGAAGCAGCAAAGCTTGGATTTACCAAGGTCTATGCTCCTAAAAATGCTTT
GCAAGGCATTGATATCCCTCAAGGTATTGAGGTTGTCGGAGTGACTACGGTTGGTCAGGTTTTAAAGGCAGTTTTTAGCT
AG
ATGGCAAAGAAAAAAGCAACCTTTATCTGTCAGGAGTGTGGCTACCAGTCGCCAAAGTATTTAGGGCGCTGTCCAAATTG
CTCGGCCTGGTCTTCTTTTGTGGAAGAAGTAGAGGTCAAAGAAGTCAAAAATGCCCGTGTTAGTCTAGCTGGAGAAAAGT
CCAGACCGGTTAAACTAAAAGATGTGGATAATATTAGTTATCACAGAACACAGACTGACATGTCTGAATTTAATAGAGTT
CTTGGAGGGGGTGTGGTTCCTGGAAGCTTGATTTTAATTGGTGGTGATCCAGGTATTGGAAAATCCACCTTACTCTTGCA
GGTATCCACGCAGCTCGCTAATAAGGGAACGGTTCTCTATGTGTCTGGGGAAGAATCAGCAGAGCAGATTAAACTGCGGA
GTGAGCGTCTGGGTGATATTGACAATGAATTTTACCTCTATGCCGAAACCAATATGCAAGCTATTCGCACAGAAATTGAA
AATATTAAACCAGATTTTTTAATTATTGACTCCATTCAGACTATCATGAGCCCTGATATTACAGGTGTTCAAGGATCAGT
CAGTCAGGTGAGAGAAGTCACTGCAGAATTGATGCAGCTTGCAAAGACGAACAACATTGCAACCTTTATTGTGGGTCATG
TCACCAAGGAAGGAACCTTGGCTGGGCCTCGTATGTTAGAACATATGGTGGATACCGTTCTCTACTTTGAAGGGGAAAGG
CATCACACCTTTCGCATTCTGCGGGCTGTGAAAAACCGCTTTGGCTCCACTAATGAGATTGGCATCTTTGAAATGCAGTC
TGGCGGTTTGGTAGAGGTCTTAAATCCTAGTCAAGTCTTTTTAGAGGAACGCTTAGATGGGGCAACAGGATCGGCTGTCG
TTGTAACGATGGAAGGAAGTCGTCCTATTTTAGCAGAGGTGCAATCTTTAGTGACACCAACCGTTTTTGGCAATGCCAGA
CGAACCACTACGGGACTTGATTTCAATCGCGTAAGCCTAATAATGGCAGTTTTAGAAAAGCGCTGTGGTTTACTCTTACA
AAATCAAGATGCCTACCTCAAGTCGGCTGGTGGTGTCAAACTAGACGAACCTGCCATTGATTTGGCAGTCGCTGTGGCTA
TCGCATCCAGTTATAAGGAAAAACCAACCAGCCCTCAAGAAGCTTTCTTAGGCGAGATCGGGTTAACAGGTGAGATTCGG
CGAGTGACCCGTATTGAGCAACGGATTAATGAAGCAGCAAAGCTTGGATTTACCAAGGTCTATGCTCCTAAAAATGCTTT
GCAAGGCATTGATATCCCTCAAGGTATTGAGGTTGTCGGAGTGACTACGGTTGGTCAGGTTTTAAAGGCAGTTTTTAGCT
AG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| radA | Streptococcus mitis NCTC 12261 |
85.872 |
100 |
0.859 |
| radA | Streptococcus pneumoniae D39 |
85.651 |
100 |
0.857 |
| radA | Streptococcus pneumoniae R6 |
85.651 |
100 |
0.857 |
| radA | Streptococcus pneumoniae Rx1 |
85.651 |
100 |
0.857 |
| radA | Streptococcus mitis SK321 |
85.651 |
100 |
0.857 |
| radA | Streptococcus pneumoniae TIGR4 |
85.651 |
100 |
0.857 |
| radA | Bacillus subtilis subsp. subtilis str. 168 |
61.369 |
100 |
0.614 |