Detailed information    

insolico Bioinformatically predicted

Overview

Name   comS   Type   Regulator
Locus tag   H7674_RS09310 Genome accession   NZ_AP023388
Coordinates   53552..53647 (+) Length   31 a.a.
NCBI ID   WP_198462994.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NIH35     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 48552..58647
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7674_RS00315 (SPNIH35_00280) purK 48621..49694 (+) 1074 WP_021340856.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  H7674_RS00320 (SPNIH35_00290) - 49696..51114 (+) 1419 WP_011888524.1 hypothetical protein -
  H7674_RS00325 (SPNIH35_00300) purB 51134..52426 (+) 1293 WP_011284409.1 adenylosuccinate lyase -
  H7674_RS00330 (SPNIH35_00310) comR 52557..53468 (+) 912 WP_002986681.1 transcriptional regulator Rgg4/ComR Regulator
  H7674_RS09310 comS 53552..53647 (+) 96 WP_198462994.1 quorum-sensing system DWW-type pheromone Regulator
  H7674_RS00335 (SPNIH35_00320) ruvB 53694..54692 (+) 999 WP_011054100.1 Holliday junction branch migration DNA helicase RuvB -
  H7674_RS00340 (SPNIH35_00330) - 54830..55267 (+) 438 WP_002994668.1 low molecular weight protein-tyrosine-phosphatase -
  H7674_RS00345 (SPNIH35_00340) - 55290..55691 (+) 402 WP_002986671.1 MORN repeat-containing protein -
  H7674_RS00350 (SPNIH35_00350) - 55688..57463 (+) 1776 WP_011284411.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 31 a.a.        Molecular weight: 3857.66 Da        Isoelectric Point: 10.0436

>NTDB_id=82760 H7674_RS09310 WP_198462994.1 53552..53647(+) (comS) [Streptococcus pyogenes strain NIH35]
MLKKYKYYFIFAALLSFKVVQELSAVDWWRL

Nucleotide


Download         Length: 96 bp        

>NTDB_id=82760 H7674_RS09310 WP_198462994.1 53552..53647(+) (comS) [Streptococcus pyogenes strain NIH35]
ATGTTAAAAAAGTATAAGTACTATTTTATATTCGCAGCTCTACTATCTTTTAAAGTAGTTCAAGAGCTTAGTGCTGTTGA
CTGGTGGCGATTATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus pyogenes MGAS8232

100

100

1
  comS Streptococcus pyogenes MGAS315

45.161

100

0.452

Multiple sequence alignment