Detailed information    

insolico Bioinformatically predicted

Overview

Name   treR   Type   Regulator
Locus tag   H7674_RS08465 Genome accession   NZ_AP023388
Coordinates   1744017..1744730 (+) Length   237 a.a.
NCBI ID   WP_002982243.1    Uniprot ID   A0A9X5LXW4
Organism   Streptococcus pyogenes strain NIH35     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1739017..1749730
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7674_RS08455 (SPNIH35_16210) treC 1740086..1741714 (-) 1629 WP_011285257.1 alpha,alpha-phosphotrehalase -
  H7674_RS08460 (SPNIH35_16220) treP 1741782..1743806 (-) 2025 WP_011285258.1 PTS system trehalose-specific EIIBC component -
  H7674_RS08465 (SPNIH35_16230) treR 1744017..1744730 (+) 714 WP_002982243.1 trehalose operon repressor Regulator
  H7674_RS08470 (SPNIH35_16240) - 1745009..1745346 (-) 338 Protein_1630 winged helix-turn-helix transcriptional regulator -
  H7674_RS08475 (SPNIH35_16250) - 1745533..1746390 (+) 858 WP_011285260.1 VOC family protein -
  H7674_RS08480 (SPNIH35_16260) yaaA 1746432..1747163 (+) 732 WP_011285261.1 peroxide stress protein YaaA -
  H7674_RS08485 (SPNIH35_16270) nrdG 1747337..1747951 (-) 615 WP_002982219.1 anaerobic ribonucleoside-triphosphate reductase activating protein -
  H7674_RS08490 (SPNIH35_16280) - 1747951..1748460 (-) 510 WP_011285262.1 GNAT family N-acetyltransferase -
  H7674_RS08495 (SPNIH35_16290) - 1748469..1749404 (-) 936 WP_002992828.1 Gfo/Idh/MocA family protein -
  H7674_RS08500 (SPNIH35_16300) - 1749433..1749579 (-) 147 WP_002982210.1 hypothetical protein -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27592.78 Da        Isoelectric Point: 9.6226

>NTDB_id=82755 H7674_RS08465 WP_002982243.1 1744017..1744730(+) (treR) [Streptococcus pyogenes strain NIH35]
MTKYERIYKDLETKINKDFYKEGDFLPTEIELSQQYQASRDTVRKALSLLTKAGLILKKQGRGTQVIKHHQIMFPISELT
SYQELVSYSNLDSKTNVIAIDKLIVDETLSKLTGFSKNSLVWRVTRQRVVEGVASVLDIDYLSKTLVPIMTREIAEHSIY
QYLEKELHLAIDFALKEVTIDQITDRDKILLDLGSDQHVVSVKSKVYLSNNNQFQFTESRHKLEKFKFLDFARRRPK

Nucleotide


Download         Length: 714 bp        

>NTDB_id=82755 H7674_RS08465 WP_002982243.1 1744017..1744730(+) (treR) [Streptococcus pyogenes strain NIH35]
ATGACAAAGTATGAACGTATTTATAAAGACCTCGAAACAAAAATAAACAAAGACTTTTACAAAGAAGGGGATTTTTTACC
TACTGAAATAGAATTGAGTCAACAATACCAAGCTAGCCGAGATACCGTCCGCAAGGCTCTCTCACTTCTCACAAAGGCAG
GTCTTATCCTCAAAAAACAAGGACGTGGCACCCAAGTGATTAAACATCATCAGATCATGTTCCCTATCTCAGAACTAACT
AGTTATCAGGAACTCGTCTCTTACTCAAATCTAGATTCTAAGACCAACGTCATTGCCATTGATAAACTGATTGTGGATGA
GACACTTTCAAAATTGACCGGTTTTAGCAAAAACAGCTTGGTCTGGCGTGTTACACGCCAACGCGTTGTTGAGGGTGTGG
CTTCCGTCTTAGACATTGATTACCTTAGTAAAACTTTGGTGCCAATAATGACAAGGGAAATCGCAGAGCATTCTATTTAT
CAATATTTGGAAAAGGAACTCCATCTCGCCATTGACTTTGCCCTCAAAGAGGTTACCATTGACCAAATAACCGATCGTGA
TAAAATTTTACTTGACCTTGGATCAGACCAACATGTTGTTTCCGTCAAATCCAAAGTCTACCTTTCCAATAATAACCAAT
TCCAATTCACCGAGAGTCGCCATAAACTGGAAAAATTTAAATTTTTAGATTTTGCTCGGCGCAGACCAAAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, gntR family (GntR)

(3-66)

UTRA domain (UTRA)

(91-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  treR Streptococcus mutans UA159

68.803

98.734

0.679

Multiple sequence alignment